BR9913850A - Gene ly6h - Google Patents

Gene ly6h

Info

Publication number
BR9913850A
BR9913850A BR9913850-6A BR9913850A BR9913850A BR 9913850 A BR9913850 A BR 9913850A BR 9913850 A BR9913850 A BR 9913850A BR 9913850 A BR9913850 A BR 9913850A
Authority
BR
Brazil
Prior art keywords
gene
expression vector
product
disease
ly6h gene
Prior art date
Application number
BR9913850-6A
Other languages
English (en)
Inventor
Masato Horie
Keiichi Okutomi
Yoshihiro Taniguchi
Mikio Suzuki
Yutaka Ohbuchi
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of BR9913850A publication Critical patent/BR9913850A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)

Abstract

Patente de Invenção: "GENE LY6H". A presente invenção proporciona um gene específico de cérebro, de utilidade no tratamento, por exemplo, da doença de Alzheimer, que compreende uma seq³ência de nucleotídeo de acordo com a seq³ência de aminoácido mostrada na SEQ ID N°: 1 e de fragmentos da mesma; um vetor de expressão que compreende o gene; uma célula hospedeira compreendendo o vetor de expressão; um produto de expressão do gene; um anticorpo contra o produto; uma composição terapêutica e profilática para doença neurodegenerativa; e similares.
BR9913850-6A 1998-09-17 1999-09-16 Gene ly6h BR9913850A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26355098 1998-09-17
PCT/JP1999/005039 WO2000017345A1 (fr) 1998-09-17 1999-09-16 Gene ly6h

Publications (1)

Publication Number Publication Date
BR9913850A true BR9913850A (pt) 2001-10-23

Family

ID=17391112

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9913850-6A BR9913850A (pt) 1998-09-17 1999-09-16 Gene ly6h

Country Status (17)

Country Link
US (4) US7432363B2 (pt)
EP (1) EP1114861B8 (pt)
JP (1) JP4403443B2 (pt)
KR (1) KR100640265B1 (pt)
CN (1) CN1240834C (pt)
AT (1) ATE346923T1 (pt)
AU (1) AU767878B2 (pt)
BR (1) BR9913850A (pt)
CA (1) CA2342770C (pt)
CY (1) CY1107552T1 (pt)
DE (1) DE69934239T8 (pt)
DK (1) DK1114861T3 (pt)
ES (1) ES2276531T3 (pt)
HK (1) HK1038380A1 (pt)
ID (1) ID29573A (pt)
PT (1) PT1114861E (pt)
WO (1) WO2000017345A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4403443B2 (ja) * 1998-09-17 2010-01-27 大塚製薬株式会社 Ｌｙ６ｈ遺伝子
ES2429132T3 (es) * 2001-08-31 2013-11-13 The Rockefeller University Atividad de fosfodiesterasa y regulación de la señalización mediada por fosfodiesterasa 1-B en el cerebro
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
CN102898519B (zh) 2005-11-30 2015-10-28 Abbvie公司 抗淀粉样β蛋白的单克隆抗体及其用途
PL2289909T3 (pl) 2005-11-30 2015-04-30 Abbvie Inc Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
WO2008103962A2 (en) * 2007-02-22 2008-08-28 Genentech, Inc. Methods for detecting inflammatory bowel disease
US20100311767A1 (en) 2007-02-27 2010-12-09 Abbott Gmbh & Co. Kg Method for the treatment of amyloidoses
WO2011016861A2 (en) 2009-08-05 2011-02-10 Intra-Cellular Therapies, Inc. Novel regulatory proteins and inhibitors
EP2558494B1 (en) 2010-04-15 2018-05-23 AbbVie Inc. Amyloid-beta binding proteins
US9062101B2 (en) 2010-08-14 2015-06-23 AbbVie Deutschland GmbH & Co. KG Amyloid-beta binding proteins
US20140286910A1 (en) * 2013-03-19 2014-09-25 Nikolai Tankovich Stem cells and methods incorporating environmental factors as a means for enhancing stem cell proliferation and plasticity
CN105385754B (zh) * 2015-10-28 2018-11-06 北京泱深生物信息技术有限公司 一种与胆管癌相关的分子标记物
KR102232200B1 (ko) * 2019-03-13 2021-03-25 아주대학교산학협력단 알츠하이머치매 진단 바이오마커

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011912A (en) 1986-12-19 1991-04-30 Immunex Corporation Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
JPH0348696A (ja) * 1989-07-14 1991-03-01 Toray Ind Inc ヒトリンパ球表面抗原およびそれをコードする遺伝子
AU4594696A (en) * 1995-11-13 1997-06-05 Human Genome Sciences, Inc. Human stem cell antigen 2
JP2002500009A (ja) * 1997-12-31 2002-01-08 インサイト・ファーマスーティカルズ・インコーポレイテッド ヒトシグナルペプチド含有タンパク質
JP4403443B2 (ja) * 1998-09-17 2010-01-27 大塚製薬株式会社 Ｌｙ６ｈ遺伝子

Also Published As

Publication number Publication date
EP1114861A1 (en) 2001-07-11
CA2342770C (en) 2011-06-21
DE69934239T2 (de) 2007-06-28
CN1240834C (zh) 2006-02-08
CA2342770A1 (en) 2000-03-30
DE69934239D1 (de) 2007-01-11
CN1318099A (zh) 2001-10-17
PT1114861E (pt) 2007-01-31
JP4403443B2 (ja) 2010-01-27
KR20010085801A (ko) 2001-09-07
EP1114861B8 (en) 2008-10-01
ID29573A (id) 2001-09-06
DK1114861T3 (da) 2007-03-19
CY1107552T1 (el) 2013-03-13
KR100640265B1 (ko) 2006-10-31
US20100261880A1 (en) 2010-10-14
ES2276531T3 (es) 2007-06-16
EP1114861B1 (en) 2006-11-29
EP1114861A4 (en) 2004-10-13
US7582732B2 (en) 2009-09-01
US7432363B2 (en) 2008-10-07
US20090017479A1 (en) 2009-01-15
DE69934239T8 (de) 2007-12-06
ATE346923T1 (de) 2006-12-15
HK1038380A1 (en) 2002-03-15
AU767878B2 (en) 2003-11-27
US20040254340A1 (en) 2004-12-16
US20080275218A1 (en) 2008-11-06
WO2000017345A1 (fr) 2000-03-30
AU5651899A (en) 2000-04-10

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10 (IX), 13, 15 E 25 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.