BR9913850A - Gene ly6h - Google Patents
Gene ly6hInfo
- Publication number
- BR9913850A BR9913850A BR9913850-6A BR9913850A BR9913850A BR 9913850 A BR9913850 A BR 9913850A BR 9913850 A BR9913850 A BR 9913850A BR 9913850 A BR9913850 A BR 9913850A
- Authority
- BR
- Brazil
- Prior art keywords
- gene
- expression vector
- product
- disease
- ly6h gene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
Abstract
Patente de Invenção: "GENE LY6H". A presente invenção proporciona um gene específico de cérebro, de utilidade no tratamento, por exemplo, da doença de Alzheimer, que compreende uma seq³ência de nucleotídeo de acordo com a seq³ência de aminoácido mostrada na SEQ ID N°: 1 e de fragmentos da mesma; um vetor de expressão que compreende o gene; uma célula hospedeira compreendendo o vetor de expressão; um produto de expressão do gene; um anticorpo contra o produto; uma composição terapêutica e profilática para doença neurodegenerativa; e similares.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP26355098 | 1998-09-17 | ||
PCT/JP1999/005039 WO2000017345A1 (fr) | 1998-09-17 | 1999-09-16 | Gene ly6h |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9913850A true BR9913850A (pt) | 2001-10-23 |
Family
ID=17391112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9913850-6A BR9913850A (pt) | 1998-09-17 | 1999-09-16 | Gene ly6h |
Country Status (17)
Country | Link |
---|---|
US (4) | US7432363B2 (pt) |
EP (1) | EP1114861B8 (pt) |
JP (1) | JP4403443B2 (pt) |
KR (1) | KR100640265B1 (pt) |
CN (1) | CN1240834C (pt) |
AT (1) | ATE346923T1 (pt) |
AU (1) | AU767878B2 (pt) |
BR (1) | BR9913850A (pt) |
CA (1) | CA2342770C (pt) |
CY (1) | CY1107552T1 (pt) |
DE (1) | DE69934239T8 (pt) |
DK (1) | DK1114861T3 (pt) |
ES (1) | ES2276531T3 (pt) |
HK (1) | HK1038380A1 (pt) |
ID (1) | ID29573A (pt) |
PT (1) | PT1114861E (pt) |
WO (1) | WO2000017345A1 (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4403443B2 (ja) * | 1998-09-17 | 2010-01-27 | 大塚製薬株式会社 | Ly6h遺伝子 |
ES2429132T3 (es) * | 2001-08-31 | 2013-11-13 | The Rockefeller University | Atividad de fosfodiesterasa y regulación de la señalización mediada por fosfodiesterasa 1-B en el cerebro |
DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
CN102898519B (zh) | 2005-11-30 | 2015-10-28 | Abbvie公司 | 抗淀粉样β蛋白的单克隆抗体及其用途 |
PL2289909T3 (pl) | 2005-11-30 | 2015-04-30 | Abbvie Inc | Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
WO2008103962A2 (en) * | 2007-02-22 | 2008-08-28 | Genentech, Inc. | Methods for detecting inflammatory bowel disease |
US20100311767A1 (en) | 2007-02-27 | 2010-12-09 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
WO2011016861A2 (en) | 2009-08-05 | 2011-02-10 | Intra-Cellular Therapies, Inc. | Novel regulatory proteins and inhibitors |
EP2558494B1 (en) | 2010-04-15 | 2018-05-23 | AbbVie Inc. | Amyloid-beta binding proteins |
US9062101B2 (en) | 2010-08-14 | 2015-06-23 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
US20140286910A1 (en) * | 2013-03-19 | 2014-09-25 | Nikolai Tankovich | Stem cells and methods incorporating environmental factors as a means for enhancing stem cell proliferation and plasticity |
CN105385754B (zh) * | 2015-10-28 | 2018-11-06 | 北京泱深生物信息技术有限公司 | 一种与胆管癌相关的分子标记物 |
KR102232200B1 (ko) * | 2019-03-13 | 2021-03-25 | 아주대학교산학협력단 | 알츠하이머치매 진단 바이오마커 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5011912A (en) | 1986-12-19 | 1991-04-30 | Immunex Corporation | Hybridoma and monoclonal antibody for use in an immunoaffinity purification system |
JPH0348696A (ja) * | 1989-07-14 | 1991-03-01 | Toray Ind Inc | ヒトリンパ球表面抗原およびそれをコードする遺伝子 |
AU4594696A (en) * | 1995-11-13 | 1997-06-05 | Human Genome Sciences, Inc. | Human stem cell antigen 2 |
JP2002500009A (ja) * | 1997-12-31 | 2002-01-08 | インサイト・ファーマスーティカルズ・インコーポレイテッド | ヒトシグナルペプチド含有タンパク質 |
JP4403443B2 (ja) * | 1998-09-17 | 2010-01-27 | 大塚製薬株式会社 | Ly6h遺伝子 |
-
1999
- 1999-09-16 JP JP2000574245A patent/JP4403443B2/ja not_active Expired - Fee Related
- 1999-09-16 WO PCT/JP1999/005039 patent/WO2000017345A1/ja active IP Right Grant
- 1999-09-16 EP EP99943357A patent/EP1114861B8/en not_active Expired - Lifetime
- 1999-09-16 PT PT99943357T patent/PT1114861E/pt unknown
- 1999-09-16 CA CA2342770A patent/CA2342770C/en not_active Expired - Fee Related
- 1999-09-16 ID IDW20010739A patent/ID29573A/id unknown
- 1999-09-16 ES ES99943357T patent/ES2276531T3/es not_active Expired - Lifetime
- 1999-09-16 BR BR9913850-6A patent/BR9913850A/pt not_active Application Discontinuation
- 1999-09-16 AT AT99943357T patent/ATE346923T1/de active
- 1999-09-16 DE DE69934239T patent/DE69934239T8/de active Active
- 1999-09-16 AU AU56518/99A patent/AU767878B2/en not_active Ceased
- 1999-09-16 DK DK99943357T patent/DK1114861T3/da active
- 1999-09-16 CN CNB998110191A patent/CN1240834C/zh not_active Expired - Fee Related
- 1999-09-16 KR KR1020017003354A patent/KR100640265B1/ko not_active IP Right Cessation
-
2001
- 2001-12-28 HK HK01109195A patent/HK1038380A1/xx not_active IP Right Cessation
-
2003
- 2003-12-23 US US10/743,018 patent/US7432363B2/en not_active Expired - Fee Related
-
2007
- 2007-02-02 CY CY20071100152T patent/CY1107552T1/el unknown
-
2008
- 2008-02-15 US US12/032,012 patent/US20090017479A1/en not_active Abandoned
- 2008-07-03 US US12/167,288 patent/US7582732B2/en not_active Expired - Fee Related
- 2008-09-30 US US12/242,370 patent/US20100261880A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1114861A1 (en) | 2001-07-11 |
CA2342770C (en) | 2011-06-21 |
DE69934239T2 (de) | 2007-06-28 |
CN1240834C (zh) | 2006-02-08 |
CA2342770A1 (en) | 2000-03-30 |
DE69934239D1 (de) | 2007-01-11 |
CN1318099A (zh) | 2001-10-17 |
PT1114861E (pt) | 2007-01-31 |
JP4403443B2 (ja) | 2010-01-27 |
KR20010085801A (ko) | 2001-09-07 |
EP1114861B8 (en) | 2008-10-01 |
ID29573A (id) | 2001-09-06 |
DK1114861T3 (da) | 2007-03-19 |
CY1107552T1 (el) | 2013-03-13 |
KR100640265B1 (ko) | 2006-10-31 |
US20100261880A1 (en) | 2010-10-14 |
ES2276531T3 (es) | 2007-06-16 |
EP1114861B1 (en) | 2006-11-29 |
EP1114861A4 (en) | 2004-10-13 |
US7582732B2 (en) | 2009-09-01 |
US7432363B2 (en) | 2008-10-07 |
US20090017479A1 (en) | 2009-01-15 |
DE69934239T8 (de) | 2007-12-06 |
ATE346923T1 (de) | 2006-12-15 |
HK1038380A1 (en) | 2002-03-15 |
AU767878B2 (en) | 2003-11-27 |
US20040254340A1 (en) | 2004-12-16 |
US20080275218A1 (en) | 2008-11-06 |
WO2000017345A1 (fr) | 2000-03-30 |
AU5651899A (en) | 2000-04-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1107552T1 (el) | Ly6h γονιδιο | |
WO1999053061A3 (en) | Tumor associated nucleic acids and uses therefor | |
DE69636866D1 (en) | Reverse "two-hybrid"-systeme | |
CY1106806T1 (el) | Dna και πολυπεπτιδια ανθρωπινης tslp | |
DK1005540T3 (da) | IKK-beta-proteiner, nukleinsyrer og fremgangsmåder | |
ATE394484T1 (de) | Smad 6 und dessen anwendungen | |
DE69635207D1 (de) | Auf Chromosom 1 lokalisiertes Gen dessen Genprodukt mit der Alzheimerschen Krankheit assoziiert ist. | |
IL135688A0 (en) | Human checkpoint kinase, hcds1, compositions and methods | |
WO2003011898A3 (fr) | Peptides synthetiques ou naturels liant la proteine phosphatase 2a, methode d'identification et utilisations | |
WO2002004677A3 (en) | Methods for diagnosis and treatment of psychiatric disorders | |
WO2000003004A3 (en) | Presenilin 2 specific ribozyme | |
WO1997002730A3 (en) | Enamel matrix related polypeptide | |
AU2001238064A1 (en) | 18477, a human protein kinase and uses therefor | |
EP1090995A3 (en) | Mycoplasma hyopneumoniae antigen MHP3, gene encoding it and uses thereof | |
EP0816498A3 (en) | Excitatory amino acid receptor protein and related nucleic acid compounds | |
WO2004003170A3 (en) | Agents capable of inhibiting ras and uses thereof | |
WO2000008143A3 (de) | Gen isoliert auf dem kurzen arm des menschlichen chromosoms 17 | |
AU2002350406A1 (en) | Identification of ses-3 (spr-5) in c. elegans and the uses of the same | |
EP1219706A3 (en) | Production processes for recombinant wolinella succinogenes asparaginase | |
AU2002314193A1 (en) | Identification of ses-1 and the uses of the same | |
WO2002000827A3 (fr) | Nouveau polypeptide, proteine de methylation d'adn-cysteine methyl-transferase 10, et polynucleotide codant ce polypeptide |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10 (IX), 13, 15 E 25 DA LPI. |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |