BR9911768A - Remédio com efeitos antidepressivos - Google Patents

Remédio com efeitos antidepressivos

Info

Publication number
BR9911768A
BR9911768A BR9911768-1A BR9911768A BR9911768A BR 9911768 A BR9911768 A BR 9911768A BR 9911768 A BR9911768 A BR 9911768A BR 9911768 A BR9911768 A BR 9911768A
Authority
BR
Brazil
Prior art keywords
remedy
antidepressant effects
effects
sertraline
propylamino
Prior art date
Application number
BR9911768-1A
Other languages
English (en)
Inventor
Jerszy Maj
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of BR9911768A publication Critical patent/BR9911768A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Patente de Invenção: <B>"REMéDIO COM EFEITOS ANTIDEPRESSIVOS"<D>. A presente invenção refere-se ao uso de 2-amino-4,5,6,7-tetrahidro-6-n-propilamino-benzotiazol, o enantiómero (+) ou (-) do mesmo ou um de seus sais farmacologicamente aceitáveis em conjunto com sertralina para o tratamento aprimorado de depressão e estados depressivos.
BR9911768-1A 1998-07-07 1999-07-02 Remédio com efeitos antidepressivos BR9911768A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19830201A DE19830201A1 (de) 1998-07-07 1998-07-07 Mittel mit antidepressiver Wirkung
PCT/EP1999/004595 WO2000002542A2 (de) 1998-07-07 1999-07-02 Mittel mit antidepressiver wirkung, enthaltend pramipexol und ein weiteres antidepressivum

Publications (1)

Publication Number Publication Date
BR9911768A true BR9911768A (pt) 2001-04-03

Family

ID=7873155

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9911768-1A BR9911768A (pt) 1998-07-07 1999-07-02 Remédio com efeitos antidepressivos

Country Status (33)

Country Link
US (1) US6255329B1 (pt)
EP (1) EP1093369B1 (pt)
JP (1) JP2002520273A (pt)
KR (1) KR100557692B1 (pt)
CN (1) CN1230168C (pt)
AR (1) AR019896A1 (pt)
AT (1) ATE228365T1 (pt)
AU (1) AU762128B2 (pt)
BG (1) BG64972B1 (pt)
BR (1) BR9911768A (pt)
CA (1) CA2336833C (pt)
CZ (1) CZ294087B6 (pt)
DE (2) DE19830201A1 (pt)
DK (1) DK1093369T3 (pt)
EA (1) EA003142B1 (pt)
EE (1) EE04296B1 (pt)
ES (1) ES2183583T3 (pt)
HK (1) HK1037976A1 (pt)
HU (1) HUP0103922A3 (pt)
ID (1) ID27776A (pt)
IL (1) IL140603A0 (pt)
MY (1) MY117969A (pt)
NO (1) NO20010064L (pt)
NZ (1) NZ509729A (pt)
PL (1) PL195043B1 (pt)
PT (1) PT1093369E (pt)
RS (1) RS49795B (pt)
SK (1) SK284923B6 (pt)
TR (1) TR200100146T2 (pt)
TW (1) TW592698B (pt)
WO (1) WO2000002542A2 (pt)
YU (1) YU401A (pt)
ZA (1) ZA200100090B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2301899C (en) * 1998-07-27 2008-11-18 Boehringer Ingelheim Pharma Kg Agent with an antidepressant activity
WO2002069974A1 (en) * 2001-03-05 2002-09-12 Andrew Holman Administration of sleep restorative agents
DE10138275A1 (de) * 2001-08-10 2003-02-27 Boehringer Ingelheim Pharma Verbindungen zur Beseitigung der Anhedonie
US20060281797A1 (en) * 2001-12-11 2006-12-14 University Of Virginia Patent Foundation Neurorestoration with R(+) Pramipexole
EP2305253A1 (en) * 2001-12-11 2011-04-06 University Of Virginia Patent Foundation Use of pramipexole to treat amyotrophic lateral sclerosis
DE10334187A1 (de) * 2003-07-26 2005-03-03 Schwarz Pharma Ag Substituierte 2-Aminotetraline zur Behandlung von Depressionen
DE10334188B4 (de) * 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
JP2007518754A (ja) * 2004-01-22 2007-07-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング モノアミン神経伝達物質再取込みインヒビターとドーパミンアゴニストを含む医薬組成物
DE602006009670D1 (de) * 2005-08-15 2009-11-19 Univ Virginia Neurorestauration mit r(+) pramipexol
US8518926B2 (en) 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
PL2026803T3 (pl) 2006-05-16 2012-05-31 Knopp Neurosciences Inc Kompozycje R(+) i S(-) pramipeksolu i sposoby ich zastosowania
US20080254118A1 (en) * 2007-04-11 2008-10-16 Hans-Werner Wernersbach Process for preparing pramipexole dihydrochloride tablets
US8524695B2 (en) 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
RU2454409C2 (ru) 2007-03-14 2012-06-27 Нопп Ньюросайенсиз, Инк. Синтез хирально очищенных замещенных бензотиазолдиаминов
US20080254117A1 (en) * 2007-04-10 2008-10-16 Noel Cotton Process for preparing pramipexole dihydrochloride tablets
KR20110071064A (ko) 2008-08-19 2011-06-28 크놉 뉴로사이언시스 인코포레이티드 (r)-프라미펙솔을 사용하는 조성물 및 방법
WO2010028207A2 (en) 2008-09-05 2010-03-11 Supernus Pharmaceuticals, Inc. Method of treatment of attention deficit/hyperactivity disorder (adhd)
EP2424539A4 (en) * 2009-04-30 2012-09-19 Supernus Pharmaceuticals Inc PROCESS FOR TREATING DEPRESSION
US9512096B2 (en) 2011-12-22 2016-12-06 Knopp Biosciences, LLP Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
AU2013217013B2 (en) 2012-02-08 2017-04-20 Supernus Pharmaceuticals, Inc. Modified release formulations of viloxazine
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
SI3019167T1 (sl) 2013-07-12 2021-04-30 Knopp Biosciences Llc Zdravljenje povišanih ravni eozinofilcev in / ali bazofilcev
US9763918B2 (en) 2013-08-13 2017-09-19 Knopp Biosciences Llc Compositions and methods for treating chronic urticaria
WO2015023786A1 (en) 2013-08-13 2015-02-19 Knopp Biosciences Llc Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders
AU2018251604B2 (en) 2017-04-10 2022-04-14 Chase Therapeutics Corporation NK1-antagonist combination and method for treating synucleinopathies
EP3645120A4 (en) 2017-06-30 2021-03-24 Chase Pharmaceuticals Corporation NK-1 ANTAGONIST COMPOSITIONS AND METHODS OF USE IN THE TREATMENT OF DEPRESSION
CN110028464B (zh) * 2019-04-26 2022-11-18 浙江海洋大学 一种南极真菌次级代谢衍生物BTZ-one及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
ATE45735T1 (de) * 1984-12-22 1989-09-15 Thomae Gmbh Dr K Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arnzneimittel.
DE3843227A1 (de) * 1988-12-22 1990-07-05 Boehringer Ingelheim Kg Neue verwendung von 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzthiazol
US4962128A (en) * 1989-11-02 1990-10-09 Pfizer Inc. Method of treating anxiety-related disorders using sertraline
DE3937271A1 (de) * 1989-11-09 1991-05-16 Boehringer Ingelheim Kg Transdermale applikation von 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzothiazol
US5248699A (en) * 1992-08-13 1993-09-28 Pfizer Inc. Sertraline polymorph
DE4241013A1 (de) * 1992-12-05 1994-06-09 Boehringer Ingelheim Kg Verwendung von 2-Amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol als Arzneimittel mit antidepressiver Wirkung
JP3947582B2 (ja) * 1995-08-15 2007-07-25 中外製薬株式会社 不安神経症治療剤
EA001485B1 (ru) * 1996-03-29 2001-04-23 Пфайзер Инк. Производные бензил(иден)-лактамов, их получение и применение в качестве селективных (ант)агонистов рецепторов 5-htи/или 5-ht
ATE282417T1 (de) * 1996-12-02 2004-12-15 Merck Sharp & Dohme Die verwendung von nk-1 rezeptor antagonisten für die behandlung von bewegungsstörungen
EP1047436B1 (en) * 1998-01-13 2009-10-21 Synchroneuron, LLC N-acetylhomotaurinates for use in treating hyperkinesias

Also Published As

Publication number Publication date
PL195043B1 (pl) 2007-08-31
NZ509729A (en) 2003-06-30
CZ200177A3 (en) 2001-06-13
EA200100084A1 (ru) 2001-08-27
CN1230168C (zh) 2005-12-07
WO2000002542A2 (de) 2000-01-20
US6255329B1 (en) 2001-07-03
TR200100146T2 (tr) 2001-07-23
YU401A (sh) 2003-10-31
AR019896A1 (es) 2002-03-20
DK1093369T3 (da) 2002-12-16
SK112001A3 (en) 2001-10-08
DE59903556D1 (de) 2003-01-09
EE04296B1 (et) 2004-06-15
EE200100014A (et) 2002-06-17
EA003142B1 (ru) 2003-02-27
ID27776A (id) 2001-04-26
DE19830201A1 (de) 2000-01-13
AU5030399A (en) 2000-02-01
CZ294087B6 (cs) 2004-10-13
PL345842A1 (en) 2002-01-14
BG105112A (en) 2001-10-31
SK284923B6 (sk) 2006-02-02
WO2000002542A3 (de) 2000-06-22
IL140603A0 (en) 2002-02-10
ATE228365T1 (de) 2002-12-15
TW592698B (en) 2004-06-21
NO20010064L (no) 2001-03-02
ZA200100090B (en) 2002-04-04
KR20010079491A (ko) 2001-08-22
MY117969A (en) 2004-08-30
ES2183583T3 (es) 2003-03-16
PT1093369E (pt) 2003-03-31
JP2002520273A (ja) 2002-07-09
AU762128B2 (en) 2003-06-19
HUP0103922A3 (en) 2002-08-28
EP1093369A2 (de) 2001-04-25
NO20010064D0 (no) 2001-01-05
BG64972B1 (bg) 2006-11-30
HK1037976A1 (en) 2002-03-01
HUP0103922A2 (hu) 2002-03-28
RS49795B (sr) 2008-06-05
CA2336833C (en) 2008-09-23
KR100557692B1 (ko) 2006-03-07
CA2336833A1 (en) 2000-01-20
EP1093369B1 (de) 2002-11-27
CN1308533A (zh) 2001-08-15

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE NAO ATENDE AOS REQUISITOS DE PATENTEABILIDADE DISPOSTO NOS ARTIGOS 8O E 13 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.