BR9907855A - Conjugado de proteìna de núcleo de hepatite b estrategicamente modificada, partìcula de proteìna, conjugado de partìculas de proteìna, conjugado de proteìna de fusão imunogênica, inóculo, e, processo para induzir anticorpos em um hospedeiro animal - Google Patents
Conjugado de proteìna de núcleo de hepatite b estrategicamente modificada, partìcula de proteìna, conjugado de partìculas de proteìna, conjugado de proteìna de fusão imunogênica, inóculo, e, processo para induzir anticorpos em um hospedeiro animalInfo
- Publication number
- BR9907855A BR9907855A BR9907855-4A BR9907855A BR9907855A BR 9907855 A BR9907855 A BR 9907855A BR 9907855 A BR9907855 A BR 9907855A BR 9907855 A BR9907855 A BR 9907855A
- Authority
- BR
- Brazil
- Prior art keywords
- protein
- conjugate
- particle
- modified hepatitis
- core
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 101710132601 Capsid protein Proteins 0.000 title abstract 4
- 108020001507 fusion proteins Proteins 0.000 title abstract 2
- 208000006454 hepatitis Diseases 0.000 title abstract 2
- 231100000283 hepatitis Toxicity 0.000 title abstract 2
- 230000002163 immunogen Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 102000037865 fusion proteins Human genes 0.000 title 1
- 239000002054 inoculum Substances 0.000 title 1
- 108090001074 Nucleocapsid Proteins Proteins 0.000 abstract 3
- 208000002672 hepatitis B Diseases 0.000 abstract 3
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 238000011081 inoculation Methods 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/02—Hepadnaviridae, e.g. hepatitis B virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/788—Of specified organic or carbon-based composition
- Y10S977/795—Composed of biological material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/84—Manufacture, treatment, or detection of nanostructure
- Y10S977/894—Manufacture, treatment, or detection of nanostructure having step or means utilizing biological growth
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
- Y10S977/917—Vaccine
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7453798P | 1998-02-12 | 1998-02-12 | |
PCT/US1999/003055 WO1999040934A1 (en) | 1998-02-12 | 1999-02-11 | Strategically modified hepatitis b core proteins and their derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9907855A true BR9907855A (pt) | 2001-04-24 |
Family
ID=22120092
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9907855-4A BR9907855A (pt) | 1998-02-12 | 1999-02-11 | Conjugado de proteìna de núcleo de hepatite b estrategicamente modificada, partìcula de proteìna, conjugado de partìculas de proteìna, conjugado de proteìna de fusão imunogênica, inóculo, e, processo para induzir anticorpos em um hospedeiro animal |
Country Status (20)
Country | Link |
---|---|
US (1) | US6231864B1 (pt) |
EP (1) | EP1054689B1 (pt) |
JP (1) | JP4480268B2 (pt) |
KR (1) | KR100581991B1 (pt) |
CN (1) | CN100387622C (pt) |
AT (1) | ATE249240T1 (pt) |
AU (1) | AU767144B2 (pt) |
BR (1) | BR9907855A (pt) |
CA (1) | CA2320488C (pt) |
CZ (1) | CZ302092B6 (pt) |
DE (1) | DE69911175T2 (pt) |
DK (1) | DK1054689T3 (pt) |
ES (1) | ES2207177T3 (pt) |
HK (1) | HK1038306A1 (pt) |
ID (1) | ID26669A (pt) |
IL (2) | IL137766A0 (pt) |
NZ (1) | NZ506245A (pt) |
PT (1) | PT1054689E (pt) |
TR (1) | TR200002338T2 (pt) |
WO (1) | WO1999040934A1 (pt) |
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US5143726A (en) | 1986-12-09 | 1992-09-01 | The Scripps Research Institute | T cell epitopes of the hepatitis B virus nucleocapsid protein |
GB8903313D0 (en) * | 1989-02-14 | 1989-04-05 | Wellcome Found | Conjugates |
NZ235315A (en) * | 1989-09-19 | 1991-09-25 | Wellcome Found | Chimaeric hepadnavirus core antigen proteins and their construction |
US5840303A (en) * | 1991-08-26 | 1998-11-24 | The Scripps Research Foundation | Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus |
WO1998009649A1 (en) * | 1996-09-03 | 1998-03-12 | The General Hospital Corporation | Inhibition of viral replication |
-
1999
- 1999-02-11 CZ CZ20002819A patent/CZ302092B6/cs not_active IP Right Cessation
- 1999-02-11 WO PCT/US1999/003055 patent/WO1999040934A1/en not_active Application Discontinuation
- 1999-02-11 NZ NZ506245A patent/NZ506245A/en unknown
- 1999-02-11 TR TR2000/02338T patent/TR200002338T2/xx unknown
- 1999-02-11 DK DK99906969T patent/DK1054689T3/da active
- 1999-02-11 AU AU26753/99A patent/AU767144B2/en not_active Ceased
- 1999-02-11 ES ES99906969T patent/ES2207177T3/es not_active Expired - Lifetime
- 1999-02-11 EP EP99906969A patent/EP1054689B1/en not_active Expired - Lifetime
- 1999-02-11 US US09/248,588 patent/US6231864B1/en not_active Expired - Lifetime
- 1999-02-11 CN CNB998049727A patent/CN100387622C/zh not_active Expired - Fee Related
- 1999-02-11 CA CA002320488A patent/CA2320488C/en not_active Expired - Fee Related
- 1999-02-11 PT PT99906969T patent/PT1054689E/pt unknown
- 1999-02-11 BR BR9907855-4A patent/BR9907855A/pt not_active IP Right Cessation
- 1999-02-11 ID IDW20001759A patent/ID26669A/id unknown
- 1999-02-11 JP JP2000531185A patent/JP4480268B2/ja not_active Expired - Lifetime
- 1999-02-11 DE DE69911175T patent/DE69911175T2/de not_active Expired - Lifetime
- 1999-02-11 KR KR1020007008848A patent/KR100581991B1/ko not_active IP Right Cessation
- 1999-02-11 AT AT99906969T patent/ATE249240T1/de active
- 1999-02-11 IL IL13776699A patent/IL137766A0/xx active IP Right Grant
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2000
- 2000-08-08 IL IL137766A patent/IL137766A/en unknown
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Also Published As
Publication number | Publication date |
---|---|
DE69911175D1 (de) | 2003-10-16 |
DK1054689T3 (da) | 2004-01-26 |
IL137766A0 (en) | 2001-10-31 |
IL137766A (en) | 2007-12-03 |
KR20010052165A (ko) | 2001-06-25 |
CA2320488C (en) | 2007-03-06 |
TR200002338T2 (tr) | 2002-06-21 |
CN1300222A (zh) | 2001-06-20 |
EP1054689B1 (en) | 2003-09-10 |
ES2207177T3 (es) | 2004-05-16 |
PT1054689E (pt) | 2003-11-28 |
NZ506245A (en) | 2003-08-29 |
CZ20002819A3 (en) | 2001-06-13 |
AU2675399A (en) | 1999-08-30 |
HK1038306A1 (en) | 2002-03-15 |
AU767144B2 (en) | 2003-10-30 |
US6231864B1 (en) | 2001-05-15 |
WO1999040934A1 (en) | 1999-08-19 |
ID26669A (id) | 2001-01-25 |
JP4480268B2 (ja) | 2010-06-16 |
CN100387622C (zh) | 2008-05-14 |
ATE249240T1 (de) | 2003-09-15 |
KR100581991B1 (ko) | 2006-05-23 |
JP2002509700A (ja) | 2002-04-02 |
EP1054689A4 (en) | 2002-02-13 |
DE69911175T2 (de) | 2004-07-29 |
CA2320488A1 (en) | 1999-08-19 |
EP1054689A1 (en) | 2000-11-29 |
CZ302092B6 (cs) | 2010-10-06 |
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