BR9815361A - Método para procução de glicerol a partir de um organismo recombinante, célula hospedeira transformada e método para produção de 1-3-propano diol a partir de um organismo recombinante - Google Patents

Método para procução de glicerol a partir de um organismo recombinante, célula hospedeira transformada e método para produção de 1-3-propano diol a partir de um organismo recombinante

Info

Publication number
BR9815361A
BR9815361A BR9815361-7A BR9815361A BR9815361A BR 9815361 A BR9815361 A BR 9815361A BR 9815361 A BR9815361 A BR 9815361A BR 9815361 A BR9815361 A BR 9815361A
Authority
BR
Brazil
Prior art keywords
producing
glycerol
recombinant organism
host cell
transformed host
Prior art date
Application number
BR9815361-7A
Other languages
English (en)
Other versions
BR9815361B1 (pt
Inventor
Ramesh V Nair
Mark S Payne
Donald E Trimbur
Fernando Valle
Original Assignee
Du Pont
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Genencor Int filed Critical Du Pont
Publication of BR9815361A publication Critical patent/BR9815361A/pt
Publication of BR9815361B1 publication Critical patent/BR9815361B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C12P7/20—Glycerol
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

<B>"MéTODO PARA PRODUçãO DE GLICEROL A PARTIR DE UM ORGANISMO RECOMBINANTE, CéLULA HOSPEDEIRA TRANSFORMADA E MéTODO PARA PRODUçãO DE 1,3-PROPANO DIOL A PARTIR DE UM ORGANISMO RECOMBINANTE<D>" A presente invenção trata-se de organismos recombinantes que compreendem genes que codificam uma atividade de glicerol-3-fosfato desidrogenase e/ou de glicerol-3-fosfatase útil para a produção de glicerol a partir de uma variedade de substratos de carbono. Os organismos contêm adicionalmente disrupções nos genes endógenos que codificam proteínas que possuem atividade de glicerol quinase e glicerol desidrogenase.
BRPI9815361-7A 1997-12-02 1998-12-02 método para produção de glicerol a partir de um microorganismo recombinante e microorganismo hospedeiro transformado. BR9815361B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98278397A 1997-12-02 1997-12-02
PCT/US1998/025551 WO1999028480A1 (en) 1997-12-02 1998-12-02 Method for the production of glycerol by recombinant organisms

Publications (2)

Publication Number Publication Date
BR9815361A true BR9815361A (pt) 2000-11-21
BR9815361B1 BR9815361B1 (pt) 2010-10-05

Family

ID=25529501

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9815361-7A BR9815361B1 (pt) 1997-12-02 1998-12-02 método para produção de glicerol a partir de um microorganismo recombinante e microorganismo hospedeiro transformado.

Country Status (13)

Country Link
US (2) US7005291B1 (pt)
EP (1) EP1034278B1 (pt)
JP (1) JP4570775B2 (pt)
KR (1) KR100550203B1 (pt)
CN (1) CN1202253C (pt)
AT (1) ATE305972T1 (pt)
AU (1) AU1619199A (pt)
BR (1) BR9815361B1 (pt)
CA (1) CA2311601C (pt)
DE (1) DE69831813T2 (pt)
HK (1) HK1028419A1 (pt)
IL (1) IL136407A0 (pt)
WO (1) WO1999028480A1 (pt)

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US6852517B1 (en) 1999-08-30 2005-02-08 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
US7112724B1 (en) 1999-09-22 2006-09-26 National Research Council Of Canada Transgenic manipulation of sn-glycerol-3-phosphate and glycerol production with a feedback defective glycerol-3-phosphate dehydrogenese gene
US7759547B2 (en) 1999-09-22 2010-07-20 National Research Council Of Canada Methods of producing and growing plants having improved phosphorus utilization
US7022674B2 (en) 1999-12-16 2006-04-04 Eli Lilly And Company Polypeptide compositions with improved stability
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ATE421577T1 (de) 2001-04-04 2009-02-15 Genencor Int Entkoppelte anabole und katabole stoffwechselwege in wirtszellen
EP1383903B1 (en) 2001-04-04 2008-09-24 Genencor International, Inc. Methods for the production of ascorbic acid intermediates in host cells
ES2318016T3 (es) * 2001-11-23 2009-05-01 Cargill, Inc. Metodo y materiales para la produccion de productos organicos en celulas de especies de candida.
AU2003225123A1 (en) 2002-04-22 2003-11-03 E. I. Du Pont De Nemours And Company Promoter and plasmid system for genetic engineering
ATE493490T1 (de) 2002-10-04 2011-01-15 Du Pont Verfahren zur biologischen herstellung von 1,3- propandiol mit hoher ausbeute
WO2004033421A2 (en) 2002-10-04 2004-04-22 Genencor International, Inc. Improved production of bacterial strains
GB0301415D0 (en) * 2003-01-22 2003-02-19 Univ York Glycerol kinase
EP1731604A4 (en) * 2004-03-26 2007-04-04 Nippon Catalytic Chem Ind PROCESS FOR THE PREPARATION OF 1,3-PROPANEL AND / OR 3-HYDROXYPROPIONIC ACID
US7524660B2 (en) 2005-05-05 2009-04-28 E.I. Du Pont De Nemours And Company Utilization of fructose in microbial production strains
JP5443970B2 (ja) * 2006-03-13 2014-03-19 カーギル インコーポレイテッド ジヒドロキシアセトンリン酸からグリセロールへの経路が破壊された酵母細胞
DK2007506T3 (da) 2006-03-31 2014-06-16 Danisco Us Inc Tangentialstrømningsfiltreringsapparater, -systemer og -fremgangsmådertil separering af forbindelser
WO2008006037A2 (en) 2006-07-06 2008-01-10 Integrated Genomics, Inc. Compositions and methods for enhancing glycerol utilization
CN101528936A (zh) * 2006-10-31 2009-09-09 代谢探索者公司 以高产率从甘油生物产生1，3-丙二醇的方法
WO2008052596A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of n-butanol with high yield
JP2010110217A (ja) * 2007-02-22 2010-05-20 Ajinomoto Co Inc Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
JP5343068B2 (ja) * 2007-04-03 2013-11-13 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー ポリオールおよびイオン液体の混合物を用いる熱伝達システム
PL2205343T3 (pl) 2007-09-12 2013-12-31 Danisco Us Inc Filtracja z wewnętrzną kontrolą zanieczyszczeń
BRPI0816880A2 (pt) 2007-09-21 2015-09-08 Basf Plant Science Gmbh métodos para produzir uma planta com rendimento aumentado em comparação com uma planta do tipo selvagem correspondente, para produzir uma planta transgênica com rendimento aumentado em comparação com uma planta do tipo selvagem não transformada correspondente, para produzir uma composição agrícola, para identificar uma planta com um rendimento aumentado, e para aumentar o rendimento de uma população de plantas, molécula de ácido nucleico isolada, construção de ácido nucléico, vetor, processos para produzir um polipeptídeo, e para identificar um composto, polipeptídeo, anticorpo, núcleo de célula de planta, célula de planta, tecido de planta, material de propagação, pólen, progênie, material colhido ou planta, semente, parte de planta, planta transgênica, planta transgênica, núcleo de célula de planta transgênica, célula de planta transgênica, planta que compreende um ou mais de tais núcleos de célula de planta transgênica ou células de planta, progênie, semente ou pólen derivado de ou produzido por uma planta transgênica, composição, e, uso dos ácidos nucleicos.
MX2010006679A (es) 2007-12-17 2010-11-30 Univ Amsterdam Reduccion de co2 inducida con luz para compuestos orgánicos que sirven como combustibles o como semiproductos industriales por un autotrofo que contiene un casete genico fermentador.
US20110144377A1 (en) * 2009-06-16 2011-06-16 E. I. Du Pont Nemours And Company Process for the biological production of 3-hydroxypropionic acid with high yield
US8852903B2 (en) 2009-10-23 2014-10-07 E I Du Pont De Nemours And Company Co-metabolism of fructose and glucose in microbial production strains
US20110136190A1 (en) 2009-12-04 2011-06-09 E. I. Du Pont De Nemours And Company Recombinant bacteria for producing glycerol and glycerol-derived products from sucrose
JP2013513394A (ja) 2009-12-15 2013-04-22 ストラトリー・アーゲー 希薄水溶液から有機成分を回収するための方法
US8129170B1 (en) 2010-12-06 2012-03-06 E.I. Du Pont De Nemours And Company Recombinant bacteria having the ability to metabolize sucrose
EP2742350B1 (en) 2011-08-08 2019-10-30 The Coca-Cola Company Cell lines comprising endogenous taste receptors and their uses
US8686114B2 (en) 2012-03-05 2014-04-01 E I Du Pont De Nemours And Company Variant sucrose transporter polypeptides
US9017961B2 (en) 2012-03-05 2015-04-28 E.I. Du Pont De Nemours And Company Recombinant bacteria comprising novel sucrose transporters
US20140178954A1 (en) 2012-12-20 2014-06-26 E I Du Pont De Nemours And Company Expression of xylose isomerase activity in yeast
US9187743B2 (en) 2013-03-11 2015-11-17 E I Du Pont De Nemours And Company Bacterial xylose isomerases active in yeast cells
US8669076B1 (en) 2013-03-11 2014-03-11 E I Du Pont De Nemours And Company Cow rumen xylose isomerases active in yeast cells
US20140273105A1 (en) 2013-03-12 2014-09-18 E I Du Pont De Nemours And Company Gradient pretreatment of lignocellulosic biomass
US20150147786A1 (en) 2013-11-24 2015-05-28 E I Du Pont De Nemours And Company High force and high stress destructuring for starch biomass processing
KR20150110144A (ko) 2014-03-24 2015-10-02 삼성전자주식회사 글리세롤, 3-hp, 또는 아크릴산 생산능을 갖는 재조합 미생물 및 그를 이용하여 글리세롤, 3-hp, 또는 아크릴산을 생산하는 방법
BR112018070645A2 (pt) 2016-04-08 2019-02-05 Du Pont células de levedura recombinante, métodos para produzir uma célula de levedura e método para produzir um composto alvo
CN113881614B (zh) * 2021-09-10 2023-07-28 江苏清大智兴生物技术有限公司 一种提升1,3-丙二醇生产菌株性能的工程菌及其应用

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Also Published As

Publication number Publication date
DE69831813T2 (de) 2006-07-20
US20060286653A1 (en) 2006-12-21
US7402415B2 (en) 2008-07-22
HK1028419A1 (en) 2001-02-16
KR20010032720A (ko) 2001-04-25
DE69831813D1 (de) 2006-02-16
EP1034278A1 (en) 2000-09-13
IL136407A0 (en) 2001-06-14
CN1202253C (zh) 2005-05-18
AU1619199A (en) 1999-06-16
JP4570775B2 (ja) 2010-10-27
CA2311601A1 (en) 1999-06-10
EP1034278B1 (en) 2005-10-05
JP2001525175A (ja) 2001-12-11
CN1284132A (zh) 2001-02-14
US7005291B1 (en) 2006-02-28
BR9815361B1 (pt) 2010-10-05
CA2311601C (en) 2008-07-08
KR100550203B1 (ko) 2006-02-08
WO1999028480A1 (en) 1999-06-10
ATE305972T1 (de) 2005-10-15

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Legal Events

Date Code Title Description
B25G Requested change of headquarter approved
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 05/10/2010, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time
B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)