ATE305972T1 - Herstellungsmethode von glycerin mittels rekombinanten organismen - Google Patents

Herstellungsmethode von glycerin mittels rekombinanten organismen

Info

Publication number
ATE305972T1
ATE305972T1 AT98960642T AT98960642T ATE305972T1 AT E305972 T1 ATE305972 T1 AT E305972T1 AT 98960642 T AT98960642 T AT 98960642T AT 98960642 T AT98960642 T AT 98960642T AT E305972 T1 ATE305972 T1 AT E305972T1
Authority
AT
Austria
Prior art keywords
glycerol
production
glycerin
recombinant organisms
organisms
Prior art date
Application number
AT98960642T
Other languages
English (en)
Inventor
Ramesh V Nair
Mark S Payne
Donald E Trimbur
Fernando Valle
Original Assignee
Du Pont
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Genencor Int filed Critical Du Pont
Application granted granted Critical
Publication of ATE305972T1 publication Critical patent/ATE305972T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C12P7/20Glycerol
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
AT98960642T 1997-12-02 1998-12-02 Herstellungsmethode von glycerin mittels rekombinanten organismen ATE305972T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98278397A 1997-12-02 1997-12-02
PCT/US1998/025551 WO1999028480A1 (en) 1997-12-02 1998-12-02 Method for the production of glycerol by recombinant organisms

Publications (1)

Publication Number Publication Date
ATE305972T1 true ATE305972T1 (de) 2005-10-15

Family

ID=25529501

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98960642T ATE305972T1 (de) 1997-12-02 1998-12-02 Herstellungsmethode von glycerin mittels rekombinanten organismen

Country Status (13)

Country Link
US (2) US7005291B1 (de)
EP (1) EP1034278B1 (de)
JP (1) JP4570775B2 (de)
KR (1) KR100550203B1 (de)
CN (1) CN1202253C (de)
AT (1) ATE305972T1 (de)
AU (1) AU1619199A (de)
BR (1) BR9815361B1 (de)
CA (1) CA2311601C (de)
DE (1) DE69831813T2 (de)
HK (1) HK1028419A1 (de)
IL (1) IL136407A0 (de)
WO (1) WO1999028480A1 (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000003021A2 (en) * 1998-07-10 2000-01-20 Jens Nielsen Metabolically engineered microbial cell comprising a modified redox activity
CN101024843A (zh) 1999-08-18 2007-08-29 纳幕尔杜邦公司 用于生产高效价1,3-丙二醇的生物学方法
EP1586647A1 (de) * 1999-08-18 2005-10-19 E.I. du Pont de Nemours and Company Verfahren zur biologischen Herstellung von 1,3-propanediol
US6852517B1 (en) 1999-08-30 2005-02-08 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
US7759547B2 (en) 1999-09-22 2010-07-20 National Research Council Of Canada Methods of producing and growing plants having improved phosphorus utilization
WO2001021820A1 (en) * 1999-09-22 2001-03-29 National Research Council Of Canada Transgenic manipulation of sn-glycerol-3-phosphate and glycerol production with a feedback defective glycerol-3-phosphate dehydrogenase gene
US7022674B2 (en) 1999-12-16 2006-04-04 Eli Lilly And Company Polypeptide compositions with improved stability
US6556563B1 (en) 2000-09-11 2003-04-29 Yahoo! Inc. Intelligent voice bridging
US7095733B1 (en) 2000-09-11 2006-08-22 Yahoo! Inc. Voice integrated VOIP system
US6567419B1 (en) 2000-09-11 2003-05-20 Yahoo! Inc. Intelligent voice converter
JP2005510999A (ja) 2001-04-04 2005-04-28 ジェネンコー・インターナショナル・インク 宿主細胞における生成物の生産方法
ATE513036T1 (de) 2001-04-04 2011-07-15 Danisco Us Inc Entkoppelte anabole und katabole stoffwechselwege in wirtszellen
EP1474507B1 (de) * 2001-11-23 2008-12-31 Cargill, Inc. Verfahren und materialien zur herstellung organischer produkte in zellen von candida-spezies
JP2005523020A (ja) 2002-04-22 2005-08-04 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 遺伝子工学のためのプロモーターおよびプラスミドシステム
DE60335574D1 (de) 2002-10-04 2011-02-10 Du Pont Verfahren zur biologischen herstellung von 1,3-propandiol mit hoher ausbeute
EP2428573A3 (de) 2002-10-04 2012-06-27 Genecor International, Inc. Verbesserte Herstellung von Bakterienstämmen sowie Querverweis auf verwandte Anmeldungen
GB0301415D0 (en) * 2003-01-22 2003-02-19 Univ York Glycerol kinase
EP1731604A4 (de) * 2004-03-26 2007-04-04 Nippon Catalytic Chem Ind Verfahren zur herstellung von 1,3-propandiol und/oder 3-hydroxypropionsäure
US7524660B2 (en) 2005-05-05 2009-04-28 E.I. Du Pont De Nemours And Company Utilization of fructose in microbial production strains
US20090053782A1 (en) 2006-03-13 2009-02-26 Catherine Asleson Dundon Yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol
EP2007506B1 (de) 2006-03-31 2014-03-19 Danisco US Inc. Tangentialströmungsfiltriergeräte, systeme und verfahren zur trennung von verbindungen
EP2041267A4 (de) 2006-07-06 2009-09-02 Integrated Genomics Inc Zusammensetzungen und verfahren für erweiterte glycerinanwendung
WO2008052596A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of n-butanol with high yield
JP2010508013A (ja) * 2006-10-31 2010-03-18 メタボリック エクスプローラー グリセロールから1,3−プロパンジオールを高収量で生物学的に製造する方法
JP2010110217A (ja) * 2007-02-22 2010-05-20 Ajinomoto Co Inc L−アミノ酸生産菌及びl−アミノ酸の製造法
KR20100016135A (ko) * 2007-04-03 2010-02-12 이 아이 듀폰 디 네모아 앤드 캄파니 폴리올 및 이온성 액체의 혼합물을 사용하는 열전달 시스템
CN101918114B (zh) * 2007-09-12 2014-12-31 丹尼斯科美国公司 具有内部污损控制的过滤
EP2594646A3 (de) 2007-09-21 2013-11-06 BASF Plant Science GmbH Pflanze mit erhöhtem Ertrag
CN101918539A (zh) 2007-12-17 2010-12-15 阿姆斯特丹大学 包含发酵基因卡盒的自养生物进行光驱动的co2还原生成有机化合物以用作燃料或用作工业半成品
US20110144377A1 (en) * 2009-06-16 2011-06-16 E. I. Du Pont Nemours And Company Process for the biological production of 3-hydroxypropionic acid with high yield
US8852903B2 (en) 2009-10-23 2014-10-07 E I Du Pont De Nemours And Company Co-metabolism of fructose and glucose in microbial production strains
US20110136190A1 (en) 2009-12-04 2011-06-09 E. I. Du Pont De Nemours And Company Recombinant bacteria for producing glycerol and glycerol-derived products from sucrose
CA2783432A1 (en) 2009-12-15 2011-06-23 Stratley Ag Method for recovery of organic components from dilute aqueous solutions
US8129170B1 (en) 2010-12-06 2012-03-06 E.I. Du Pont De Nemours And Company Recombinant bacteria having the ability to metabolize sucrose
WO2013022948A1 (en) 2011-08-08 2013-02-14 The Coca-Cola Company Cell lines comprising endogenous taste receptors and their uses
US8686114B2 (en) 2012-03-05 2014-04-01 E I Du Pont De Nemours And Company Variant sucrose transporter polypeptides
US9017961B2 (en) 2012-03-05 2015-04-28 E.I. Du Pont De Nemours And Company Recombinant bacteria comprising novel sucrose transporters
US20140178954A1 (en) 2012-12-20 2014-06-26 E I Du Pont De Nemours And Company Expression of xylose isomerase activity in yeast
US9187743B2 (en) 2013-03-11 2015-11-17 E I Du Pont De Nemours And Company Bacterial xylose isomerases active in yeast cells
US8669076B1 (en) 2013-03-11 2014-03-11 E I Du Pont De Nemours And Company Cow rumen xylose isomerases active in yeast cells
US20140273105A1 (en) 2013-03-12 2014-09-18 E I Du Pont De Nemours And Company Gradient pretreatment of lignocellulosic biomass
US20150147786A1 (en) 2013-11-24 2015-05-28 E I Du Pont De Nemours And Company High force and high stress destructuring for starch biomass processing
KR20150110144A (ko) 2014-03-24 2015-10-02 삼성전자주식회사 글리세롤, 3-hp, 또는 아크릴산 생산능을 갖는 재조합 미생물 및 그를 이용하여 글리세롤, 3-hp, 또는 아크릴산을 생산하는 방법
WO2017176875A1 (en) 2016-04-08 2017-10-12 E I Du Pont De Nemours And Company Arabinose isomerases for yeast
CN113881614B (zh) * 2021-09-10 2023-07-28 江苏清大智兴生物技术有限公司 一种提升1,3-丙二醇生产菌株性能的工程菌及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2725145B1 (fr) 1994-09-30 1996-11-08 Renaud Michel Procede d'impregnation d'une eponge a l'aide d'un produit liquide ou pateux
US5686276A (en) * 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
US5599689A (en) * 1995-05-12 1997-02-04 E. I. Du Pont De Nemours And Company Process for making 1,3-propanediol from carbohydrates using mixed microbial cultures
US5633362A (en) * 1995-05-12 1997-05-27 E. I. Du Pont De Nemours And Company Production of 1,3-propanediol from glycerol by recombinant bacteria expressing recombinant diol dehydratase
FR2735145B1 (fr) 1995-06-09 1997-08-22 Agronomique Inst Nat Rech Souches de levures presentant un bilan de fermentation alcoolique des sucres modifie et leurs applications, vecteurs utilisables pour l'obtention desdites souches.
US5733749A (en) * 1995-08-14 1998-03-31 Wisconsin Alumni Research Foundation Glycerol phosphatase with stereo-specific activity
DE69739715D1 (de) * 1996-11-13 2010-02-04 Du Pont Herstellungsverfahren von 1,3-propandiol durch rekombinante organismen
KR100674074B1 (ko) * 1996-11-13 2007-01-26 이 아이 듀폰 디 네모아 앤드 캄파니 재조합 유기체에 의한 글리세롤의 생산 방법
CN101024843A (zh) * 1999-08-18 2007-08-29 纳幕尔杜邦公司 用于生产高效价1,3-丙二醇的生物学方法

Also Published As

Publication number Publication date
IL136407A0 (en) 2001-06-14
CA2311601A1 (en) 1999-06-10
CN1284132A (zh) 2001-02-14
EP1034278A1 (de) 2000-09-13
US7402415B2 (en) 2008-07-22
US20060286653A1 (en) 2006-12-21
BR9815361B1 (pt) 2010-10-05
AU1619199A (en) 1999-06-16
KR100550203B1 (ko) 2006-02-08
BR9815361A (pt) 2000-11-21
HK1028419A1 (en) 2001-02-16
DE69831813T2 (de) 2006-07-20
JP4570775B2 (ja) 2010-10-27
CN1202253C (zh) 2005-05-18
EP1034278B1 (de) 2005-10-05
KR20010032720A (ko) 2001-04-25
CA2311601C (en) 2008-07-08
JP2001525175A (ja) 2001-12-11
US7005291B1 (en) 2006-02-28
WO1999028480A1 (en) 1999-06-10
DE69831813D1 (de) 2006-02-16

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