BR9809183A - Médoto para prognóstico de doença inflamatória associada com polimorfismos de locais de gene il-1, conjunto de diagnóstico, método de determinação suscetibilidade aumentada a desordem inflamatória, e escada alélica - Google Patents

Médoto para prognóstico de doença inflamatória associada com polimorfismos de locais de gene il-1, conjunto de diagnóstico, método de determinação suscetibilidade aumentada a desordem inflamatória, e escada alélica

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Publication number
BR9809183A
BR9809183A BR9809183-2A BR9809183A BR9809183A BR 9809183 A BR9809183 A BR 9809183A BR 9809183 A BR9809183 A BR 9809183A BR 9809183 A BR9809183 A BR 9809183A
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Prior art keywords
inflammatory disorder
inflammatory
polymorphisms
prognosis
disease
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BR9809183-2A
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English (en)
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Gordon Duff
Angela Cox
Jane Nicola Camp
Saveiro Francesco De Giovine
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Interleukin Genetics Inc
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Publication of BR9809183A publication Critical patent/BR9809183A/pt

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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

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  • General Engineering & Computer Science (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

<B>"MéTODO PARA PROGNóSTICO DE DOENçA INFLAMATóRIA ASSOCIADA COM POLIMORFISMOS DE LOCAIS DE GENE IL-1, CONJUNTO DE DIAGNóSTICO, MéTODO DE DETERMINAçãO DE SUSCETIBILIDADE AUMENTADA A DESORDEM INFLAMATóRIA, E ESCADA ALéLICA"<D> Métodos, análises e conjuntos são apresentados para detectar a suscetibilidade de um paciente a uma desordem inflamatória tal como doença da artéria coronária, osteoporose, nefropatia em diabetes melito, alopecia pelada, doença de Graves, lúpus eritematoso sistêmico, esclerose de líquen, colite ulcerativa, retinopatia diabética, doença peridental, artrite crónica juvenil, especialmente iridociclite crónica, psoríase, diabetes insulino dependente e outras doenças com um componente genético IL-1. O método compreende obter uma amostra biológica de um paciente e determinar a presença ou ausência de um haplótipo específico do agrupamento de gene IL-1 que está associado com uma desordem inflamatória. A detecção de pelo menos um dos alelos no haplótipo indica uma suscetibilidade para a desordem inflamatória.
BR9809183-2A 1997-05-29 1998-05-21 Médoto para prognóstico de doença inflamatória associada com polimorfismos de locais de gene il-1, conjunto de diagnóstico, método de determinação suscetibilidade aumentada a desordem inflamatória, e escada alélica BR9809183A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9711040.7A GB9711040D0 (en) 1997-05-29 1997-05-29 Prediction of inflammatory disease
PCT/GB1998/001481 WO1998054359A1 (en) 1997-05-29 1998-05-21 Prediction of inflammatory disease associated with il-1 geneloci polymorphisms

Publications (1)

Publication Number Publication Date
BR9809183A true BR9809183A (pt) 2000-08-01

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BR9809183-2A BR9809183A (pt) 1997-05-29 1998-05-21 Médoto para prognóstico de doença inflamatória associada com polimorfismos de locais de gene il-1, conjunto de diagnóstico, método de determinação suscetibilidade aumentada a desordem inflamatória, e escada alélica

Country Status (19)

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US (4) US6268142B1 (pt)
EP (1) EP0983385B1 (pt)
JP (1) JP2002500513A (pt)
CN (1) CN1177059C (pt)
AR (1) AR016754A1 (pt)
AT (1) ATE462800T1 (pt)
AU (1) AU755107B2 (pt)
BR (1) BR9809183A (pt)
CA (1) CA2291731A1 (pt)
DE (1) DE69841588D1 (pt)
EA (1) EA199901097A1 (pt)
ES (1) ES2342992T3 (pt)
GB (1) GB9711040D0 (pt)
IL (1) IL133128A0 (pt)
NO (1) NO995803L (pt)
PL (1) PL337080A1 (pt)
TW (1) TWI236502B (pt)
WO (1) WO1998054359A1 (pt)
ZA (1) ZA984490B (pt)

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CN1177059C (zh) 2004-11-24
US6268142B1 (en) 2001-07-31
US20040152124A1 (en) 2004-08-05
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US20080187920A1 (en) 2008-08-07
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NO995803D0 (no) 1999-11-26
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