BR9610049A - Composições endoparasiticidas à base de didepsipeptídeos novos didepsipeptídeos e processos para a sua preparação - Google Patents

Composições endoparasiticidas à base de didepsipeptídeos novos didepsipeptídeos e processos para a sua preparação

Info

Publication number
BR9610049A
BR9610049A BR9610049A BR9610049A BR9610049A BR 9610049 A BR9610049 A BR 9610049A BR 9610049 A BR9610049 A BR 9610049A BR 9610049 A BR9610049 A BR 9610049A BR 9610049 A BR9610049 A BR 9610049A
Authority
BR
Brazil
Prior art keywords
new
endoparasitic
preparation
didepsipeptides
compositions based
Prior art date
Application number
BR9610049A
Other languages
English (en)
Other versions
BRPI9610049B1 (pt
Inventor
Peter Jeschke
Nobert Mencke
Juergen Scherkenbeck
Andrew Plant
Achim Harder
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BR9610049A publication Critical patent/BR9610049A/pt
Publication of BRPI9610049B1 publication Critical patent/BRPI9610049B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/58Y being a hetero atom
    • C07C275/62Y being a nitrogen atom, e.g. biuret
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/48Y being a hydrogen or a carbon atom
    • C07C275/50Y being a hydrogen or an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K11/00Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BRPI9610049A 1995-08-11 1996-07-30 didepsipeptídeos e composições endoparasiticidas à base dos mesmos BRPI9610049B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19529604A DE19529604A1 (de) 1995-08-11 1995-08-11 Endoparasitizide Mittel auf Basis von Didepsipeptiden, neue Didepsipeptide und ein Verfahren zu ihrer Herstellung
PCT/EP1996/003355 WO1997007093A1 (de) 1995-08-11 1996-07-30 Endoparasitizide mittel auf basis von didepsipeptiden, neue didepsipeptide und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
BR9610049A true BR9610049A (pt) 1999-07-06
BRPI9610049B1 BRPI9610049B1 (pt) 2017-05-02

Family

ID=7769288

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9610049A BRPI9610049B1 (pt) 1995-08-11 1996-07-30 didepsipeptídeos e composições endoparasiticidas à base dos mesmos

Country Status (26)

Country Link
US (2) US20020142969A1 (pt)
EP (1) EP0843658B1 (pt)
JP (3) JPH11511142A (pt)
KR (1) KR19990036304A (pt)
CN (2) CN1053657C (pt)
AR (1) AR003977A1 (pt)
AT (1) ATE229933T1 (pt)
AU (1) AU707123B2 (pt)
BG (1) BG64091B1 (pt)
BR (1) BRPI9610049B1 (pt)
CA (1) CA2228939C (pt)
CZ (1) CZ41698A3 (pt)
DE (2) DE19529604A1 (pt)
DK (1) DK0843658T3 (pt)
ES (1) ES2190476T3 (pt)
HK (1) HK1017340A1 (pt)
HU (1) HUP9802316A3 (pt)
MX (1) MX9801133A (pt)
NO (1) NO311566B1 (pt)
NZ (1) NZ315642A (pt)
PL (1) PL187412B1 (pt)
SK (1) SK15598A3 (pt)
TR (1) TR199800210T2 (pt)
TW (1) TW492976B (pt)
WO (1) WO1997007093A1 (pt)
ZA (1) ZA966749B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458772B1 (en) 1909-10-07 2002-10-01 Medivir Ab Prodrugs
DE19962147A1 (de) 1999-12-22 2001-06-28 Bayer Ag Schädlingsbekämpfungsmittel / PF 1022-221
DE19962145A1 (de) 1999-12-22 2001-06-28 Bayer Ag Schädlingsbekämpfungsmittel/Depsipeptide
JP2009518433A (ja) 2005-12-09 2009-05-07 イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブライ ユニバーシティー オブ エルサレム 神経保護用の低用量ラドスチギルの使用
TW200744576A (en) 2006-02-24 2007-12-16 Teva Pharma Propargylated aminoindans, processes for preparation, and uses thereof
WO2009070631A2 (en) * 2007-11-28 2009-06-04 University Of Virginia Patent Foundation Ethoid compounds for use as food additives
TW200938203A (en) * 2007-12-17 2009-09-16 Intervet Int Bv Anthelmintic agents and their use
TW201111358A (en) * 2009-06-18 2011-04-01 Intervet Int Bv Anthelmintic agents and their use

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2619247C2 (de) * 1976-04-30 1986-04-03 Eckert, Heiner, Dipl.-Chem. Dr., 8000 München Verfahren zum Schutze reaktionsfähiger Amino-, Hydroxyl- und/oder Carboxylgruppen
FR2365341A1 (fr) * 1976-09-28 1978-04-21 Synthelabo Derives de l'acide l-(phenyl-3 amino-2 propionyloxy)-2 acetique
HU181008B (en) * 1980-01-18 1983-05-30 Richter Gedeon Vegyeszet Process for producing angiotenzin-ii analogues of antagonistic activity containing sarcosyl-group at the 1-positon,and an alpha-hydroxy-carboxylic acid at the 8-position
JPS606649A (ja) * 1983-06-24 1985-01-14 Daicel Chem Ind Ltd モノマ−
DK406686D0 (da) * 1986-08-26 1986-08-26 Hans Bundgaard Carboxylsyrederivater
CA2132199C (en) * 1992-03-17 2000-01-18 Hitoshi Nishiyama Depsipeptide derivative, production thereof and use thereof
DE4317458A1 (de) * 1992-06-11 1993-12-16 Bayer Ag Verwendung von cyclischen Depsipeptiden mit 18 Ringatomen zur Bekämpfung von Endoparasiten, neue cyclische Depsipeptide mit 18 Ringatomen und Verfahren zu ihrer Herstellung
CA2155871A1 (en) * 1993-02-19 1994-09-01 Makoto Ohyama Derivatives of cyclodepsipeptide pf 1022
DE4317457A1 (de) * 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
DE4341992A1 (de) * 1993-12-09 1995-06-14 Bayer Ag Endoparasitizide Mittel auf Basis von offenkettigen Tetradepsipeptiden
DE4341991A1 (de) * 1993-12-09 1995-06-14 Bayer Ag Endoparasitizide Mittel auf Basis von offenkettigen Hexadepsipeptiden

Also Published As

Publication number Publication date
CN1199394A (zh) 1998-11-18
NO311566B1 (no) 2001-12-10
JP2014159449A (ja) 2014-09-04
NO980324D0 (no) 1998-01-26
SK15598A3 (en) 1998-09-09
AU707123B2 (en) 1999-07-01
KR19990036304A (ko) 1999-05-25
AR003977A1 (es) 1998-09-30
CN1254596A (zh) 2000-05-31
JP2010222361A (ja) 2010-10-07
DE59610011D1 (de) 2003-01-30
CA2228939C (en) 2007-01-30
EP0843658B1 (de) 2002-12-18
BG64091B1 (bg) 2003-12-31
BG102213A (en) 1998-08-31
CN1053657C (zh) 2000-06-21
HK1017340A1 (en) 1999-11-19
WO1997007093A1 (de) 1997-02-27
US20020142969A1 (en) 2002-10-03
JPH11511142A (ja) 1999-09-28
TR199800210T2 (xx) 1998-08-21
ZA966749B (en) 1997-02-18
HUP9802316A3 (en) 2001-04-28
DK0843658T3 (da) 2003-04-14
AU6739496A (en) 1997-03-12
DE19529604A1 (de) 1997-02-13
BRPI9610049B1 (pt) 2017-05-02
MX9801133A (es) 1998-05-31
NZ315642A (en) 2000-01-28
CA2228939A1 (en) 1997-02-27
NO980324L (no) 1998-03-05
EP0843658A1 (de) 1998-05-27
ATE229933T1 (de) 2003-01-15
PL324893A1 (en) 1998-06-22
ES2190476T3 (es) 2003-08-01
PL187412B1 (pl) 2004-07-30
TW492976B (en) 2002-07-01
CZ41698A3 (cs) 1998-06-17
US7772190B2 (en) 2010-08-10
HUP9802316A2 (hu) 1999-02-01
US20040034048A1 (en) 2004-02-19

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO, UMA VEZ QUE NAO ATENDE AO REQUISITO DE ATIVIDADE INVENTIVA ( ART. 8O COMBINADO COM ART. 13 DA LPI )

B12B Appeal against refusal [chapter 12.2 patent gazette]
B25A Requested transfer of rights approved

Owner name: BAYER ANIMAL HEALTH GMBH (DE)

Free format text: TRANSFERIDO DE: BAYER AKTIENGESELLSCHAFT

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B25A Requested transfer of rights approved

Owner name: BAYER INTELLECTUAL PROPERTY GMBH (DE)

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time
B24D Patent annual fee: restoration after fee payment
B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 23A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2525 DE 28-05-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.