BR9507553A - Novos antimicrobianos de quinolina 5-(amido n- heterossubstituída) - Google Patents
Novos antimicrobianos de quinolina 5-(amido n- heterossubstituída)Info
- Publication number
- BR9507553A BR9507553A BR9507553A BR9507553A BR9507553A BR 9507553 A BR9507553 A BR 9507553A BR 9507553 A BR9507553 A BR 9507553A BR 9507553 A BR9507553 A BR 9507553A BR 9507553 A BR9507553 A BR 9507553A
- Authority
- BR
- Brazil
- Prior art keywords
- heterosubstituted
- antimicrobials
- starch
- new quinoline
- quinoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/235,003 US5646163A (en) | 1992-10-30 | 1994-04-28 | Quinolone 5-(N-heterosubstituted amino) antimicrobials |
| PCT/US1995/004495 WO1995029894A1 (en) | 1994-04-28 | 1995-04-11 | Novel quinolone 5-(n-heterosubstituted amino) antimicrobials |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9507553A true BR9507553A (pt) | 1997-08-05 |
Family
ID=22883653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9507553A BR9507553A (pt) | 1994-04-28 | 1995-04-11 | Novos antimicrobianos de quinolina 5-(amido n- heterossubstituída) |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5646163A (pt) |
| EP (1) | EP0757675A1 (pt) |
| JP (1) | JPH09512549A (pt) |
| KR (1) | KR100244992B1 (pt) |
| CN (1) | CN1157611A (pt) |
| AU (1) | AU2246695A (pt) |
| BR (1) | BR9507553A (pt) |
| CA (1) | CA2188918A1 (pt) |
| FI (1) | FI964318A (pt) |
| NO (1) | NO964533L (pt) |
| WO (1) | WO1995029894A1 (pt) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100728797B1 (ko) * | 2000-09-11 | 2007-06-19 | 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 | 티로신 키나제 억제제로서의 퀴놀리논 유도체 |
| MXPA06001645A (es) * | 2003-08-12 | 2006-05-12 | Achillion Pharmaceuticals Inc | Isotiazoloquinolonas y compuestos relacionados como agentes anti-infecciosos. |
| BRPI0413964B8 (pt) | 2003-09-10 | 2021-05-25 | Kyorin Seiyaku Kk | ácido derivado do ácido carboxílico quinolona, sua composição e agente antibacterial |
| JP2008509909A (ja) * | 2004-08-11 | 2008-04-03 | ウィリアムスバーグ・ホールディングス・エルエルシー | 心毒性のない医薬化合物 |
| PE20060489A1 (es) | 2004-08-13 | 2006-06-19 | Schering Plough Ltd | Formulacion farmaceutica que comprende un antibiotico, un triazol y un corticosteroide |
| EP1802306A2 (en) * | 2004-09-17 | 2007-07-04 | Cylene Pharmaceuticals, Inc. | Quinolone analog as cell proliferation inhibitors |
| US7652134B2 (en) * | 2004-09-17 | 2010-01-26 | Cylene Pharmaceuticals, Inc. | Methods for converting quinolone esters into quinolone amides |
| EP1809639B1 (en) * | 2004-11-11 | 2009-10-14 | Achillion Pharmaceuticals, Inc. | 8a, 9-dihydro-4a-h-isothiazolo[5,4-b] quinoline-3, 4-diones and related compounds as anti-infective agents |
| US7659399B2 (en) * | 2005-01-05 | 2010-02-09 | Achillion Pharmaceuticals, Inc. | 1-thia-2,4a-diaza-cyclopenta[b]napththalene-3,4-diones and related compounds as anti-infective agents |
| US7199128B2 (en) | 2005-02-02 | 2007-04-03 | Achillion Pharmaceuticals, Inc. | 8-N-substituted-2H-isothiazolo[5,4-b]quinolizine-3,4-diones and related compounds as antiinfective agents |
| MX2007009895A (es) * | 2005-02-16 | 2007-10-03 | Achillion Pharmaceuticals Inc | Nuevas isotiazoloquinolonas y compuestos relacionados como agentes anti-infecciosos. |
| US8044204B2 (en) * | 2005-07-27 | 2011-10-25 | Achillion Pharmaceuticals, Inc. | 8-methoxy-9H-isothiazolo[5,4-b]quinoline-3,4-diones and related compounds as anti-infective agents |
| PT1928887E (pt) * | 2005-08-05 | 2015-02-12 | Senhwa Biosciences Inc | Métodos de preparação de análogos de quinolona |
| CL2007003332A1 (es) * | 2006-11-24 | 2008-06-20 | Actelion Pharmaceuticals Ltd | Compuestos derivados de heterociclos condensados; compuestos intermediarios; composicion farmaceutica; y uso en la prevencion o tratamiento de infecciones bacterianas. |
| US8183236B2 (en) * | 2007-04-12 | 2012-05-22 | University Of Southern California | Compounds with HIV-1 integrase inhibitory activity and use thereof as anti-HIV/AIDS therapeutics |
| JP5322927B2 (ja) * | 2007-05-24 | 2013-10-23 | 杏林製薬株式会社 | １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体 |
| EP2145891A1 (en) * | 2008-07-09 | 2010-01-20 | Vetoquinol S.A. | 9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials |
| NZ595448A (en) * | 2009-04-03 | 2013-01-25 | Achillion Pharmaceuticals Inc | Hydroxythienoquinolones and related compounds as anti-infective agents |
| WO2011031745A1 (en) | 2009-09-09 | 2011-03-17 | Achaogen, Inc. | Antibacterial fluoroquinolone analogs |
| CN102725274A (zh) | 2009-10-16 | 2012-10-10 | Rib-X制药公司 | 抗微生物化合物和其制备和使用方法 |
| TWI612048B (zh) * | 2009-10-16 | 2018-01-21 | 梅林塔療法公司 | 抗微生物性化合物，及製法及其用途 |
| DK2488532T3 (en) | 2009-10-16 | 2018-08-13 | Melinta Therapeutics Inc | ANTIMICROBIAL COMPOUNDS AND PROCEDURES FOR PREPARING AND USING THE SAME |
| KR20160070066A (ko) | 2013-09-09 | 2016-06-17 | 멜린타 테라퓨틱스, 인크. | 항균 화합물, 및 이의 제조 방법 및 이용 방법 |
| EP3038623A4 (en) | 2013-09-09 | 2017-04-19 | Melinta Therapeutics, Inc. | Antimicrobial compounds and methods of making and using the same |
| US10947237B2 (en) | 2015-03-11 | 2021-03-16 | BioVersys AG | Antimicrobial compounds and methods of making and using the same |
| WO2017193016A1 (en) | 2016-05-06 | 2017-11-09 | Melinta Therapeutics, Inc. | Antimicrobials and methods of making and using same |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4665079A (en) * | 1984-02-17 | 1987-05-12 | Warner-Lambert Company | Antibacterial agents |
| IE58742B1 (en) * | 1984-07-20 | 1993-11-05 | Warner Lambert Co | Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds |
| US4822801A (en) * | 1984-07-20 | 1989-04-18 | Warner-Lambert Company | 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents |
| US4623650A (en) * | 1984-12-06 | 1986-11-18 | Pfizer Inc. | Antibiotic derivatives of 7-phenyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids |
| AU594983B2 (en) * | 1985-10-29 | 1990-03-22 | Dainippon Pharmaceutical Co. Ltd. | Novel quinoline derivatives and processes for preparation thereof |
| US4954507A (en) * | 1986-10-08 | 1990-09-04 | Bristol-Myers Company | 1-tertiary-alkyl-substituted naphthyridine carboxylic acid antibacterial agents |
| DE3711193A1 (de) * | 1987-04-02 | 1988-10-13 | Bayer Ag | 5-substituierte chinolon- und naphthyridoncarbonsaeure-derivate |
| AU609974B2 (en) * | 1988-05-18 | 1991-05-09 | Warner-Lambert Company | Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids |
| JP2664950B2 (ja) * | 1988-08-31 | 1997-10-22 | 日本電気株式会社 | 入出力処理装置 |
| US4945160A (en) * | 1988-11-22 | 1990-07-31 | Warner-Lambert Company | Preparation of certain 7-substituted quinolones |
| ES2147721T3 (es) * | 1990-04-18 | 2000-10-01 | Procter & Gamble Pharma | Quinolonil lactamas antimicrobianas. |
| SK37594A3 (en) * | 1991-10-01 | 1995-02-08 | Procter & Gamble Pharma | Method of preparation of antimicrobial quinolonyl lactams |
| EG20543A (en) * | 1992-10-30 | 1999-07-31 | Procter & Gamble | Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones |
-
1994
- 1994-04-28 US US08/235,003 patent/US5646163A/en not_active Expired - Fee Related
-
1995
- 1995-04-11 BR BR9507553A patent/BR9507553A/pt not_active Application Discontinuation
- 1995-04-11 CN CN95193457A patent/CN1157611A/zh active Pending
- 1995-04-11 AU AU22466/95A patent/AU2246695A/en not_active Abandoned
- 1995-04-11 JP JP7528255A patent/JPH09512549A/ja active Pending
- 1995-04-11 CA CA002188918A patent/CA2188918A1/en not_active Abandoned
- 1995-04-11 EP EP95915652A patent/EP0757675A1/en not_active Withdrawn
- 1995-04-11 WO PCT/US1995/004495 patent/WO1995029894A1/en not_active Application Discontinuation
- 1995-04-11 KR KR1019960706138A patent/KR100244992B1/ko not_active IP Right Cessation
-
1996
- 1996-10-25 NO NO964533A patent/NO964533L/no unknown
- 1996-10-25 FI FI964318A patent/FI964318A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1995029894A1 (en) | 1995-11-09 |
| KR100244992B1 (ko) | 2000-03-02 |
| FI964318A (fi) | 1996-12-23 |
| US5646163A (en) | 1997-07-08 |
| KR970702849A (ko) | 1997-06-10 |
| CN1157611A (zh) | 1997-08-20 |
| NO964533D0 (no) | 1996-10-25 |
| EP0757675A1 (en) | 1997-02-12 |
| NO964533L (no) | 1996-12-23 |
| FI964318A0 (fi) | 1996-10-25 |
| JPH09512549A (ja) | 1997-12-16 |
| CA2188918A1 (en) | 1995-11-09 |
| AU2246695A (en) | 1995-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| FC | Decision: refusal |