BR9302426A - Processo para a separacao de uma mistura anomerica - Google Patents

Processo para a separacao de uma mistura anomerica

Info

Publication number
BR9302426A
BR9302426A BR9302426A BR9302426A BR9302426A BR 9302426 A BR9302426 A BR 9302426A BR 9302426 A BR9302426 A BR 9302426A BR 9302426 A BR9302426 A BR 9302426A BR 9302426 A BR9302426 A BR 9302426A
Authority
BR
Brazil
Prior art keywords
separating
anomeric mixture
anomeric
mixture
countersolvent
Prior art date
Application number
BR9302426A
Other languages
English (en)
Inventor
Ta-Sen Chou
Timothy James Mccarthy
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BR9302426A publication Critical patent/BR9302426A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BR9302426A 1992-06-22 1993-06-21 Processo para a separacao de uma mistura anomerica BR9302426A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/902,303 US5256797A (en) 1992-06-22 1992-06-22 Process for separating 2-deoxy-2,2-difluoro-D-ribofuranosyl alkylsulfonate anomers

Publications (1)

Publication Number Publication Date
BR9302426A true BR9302426A (pt) 1994-01-11

Family

ID=25415647

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9302426A BR9302426A (pt) 1992-06-22 1993-06-21 Processo para a separacao de uma mistura anomerica

Country Status (17)

Country Link
US (1) US5256797A (pt)
EP (1) EP0576232B1 (pt)
JP (1) JPH0656867A (pt)
KR (1) KR100302087B1 (pt)
AT (1) ATE149505T1 (pt)
BR (1) BR9302426A (pt)
CA (1) CA2098888C (pt)
CY (1) CY2091B1 (pt)
DE (1) DE69308391T2 (pt)
DK (1) DK0576232T3 (pt)
ES (1) ES2100462T3 (pt)
GR (1) GR3023060T3 (pt)
HK (1) HK1006022A1 (pt)
HU (1) HU217976B (pt)
IL (1) IL106074A (pt)
MX (1) MX9303714A (pt)
TW (1) TW233300B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9302427A (pt) * 1992-06-22 1994-01-11 Lilly Co Eli Processo estereo seletivo para a preparacao de um derivado de riboturanosila
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
YU92202A (sh) 2000-05-26 2006-01-16 Idenix (Cayman) Limited Metode i smeše za lečenje flavi virusa i pesti virusa
US7608600B2 (en) 2002-06-28 2009-10-27 Idenix Pharmaceuticals, Inc. Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
AU2003248748A1 (en) 2002-06-28 2004-01-19 Idenix (Cayman) Limited 2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
CN1849142A (zh) 2002-11-15 2006-10-18 埃迪尼克斯(开曼)有限公司 2′－支链核苷和黄病毒突变
AU2003300901A1 (en) 2002-12-12 2004-06-30 Idenix (Cayman) Limited Process for the production of 2'-branched nucleosides
JP2008503562A (ja) * 2004-06-23 2008-02-07 イデニクス（ケイマン）リミテツド フラビウイルス科による感染症を治療するための５−アザ−７−デアザプリン誘導体
US7214791B2 (en) * 2004-07-01 2007-05-08 Shenzhen Hande Technology Co., Ltd. Method for preparation of 2′-deoxy-2′, 2′-difluoro-β-cytidine or pharmaceutically acceptable salts thereof by using 1,6-anhydro-β-d-glucose as raw material
AT502221A1 (de) * 2005-07-20 2007-02-15 Pharmacon Forschung & Beratung Gmbh Homogemcitabine, verfahren zu ihrer herstellung sowie deren verwendung
EP1976382B1 (en) 2005-12-23 2013-04-24 IDENIX Pharmaceuticals, Inc. Process for preparing a synthetic intermediate for preparation of branched nucleosides
WO2007092705A2 (en) * 2006-02-07 2007-08-16 Chemagis Ltd. Process for preparing gemcitabine and associated intermediates
US20070249823A1 (en) * 2006-04-20 2007-10-25 Chemagis Ltd. Process for preparing gemcitabine and associated intermediates
US20080262215A1 (en) * 2007-04-23 2008-10-23 Chemagis Ltd. Gemcitabine production process
GB0812895D0 (en) 2008-07-15 2008-08-20 Glycom As Crystalline carbohydrate derivative

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526988A (en) * 1983-03-10 1985-07-02 Eli Lilly And Company Difluoro antivirals and intermediate therefor
US4965374A (en) * 1987-08-28 1990-10-23 Eli Lilly And Company Process for and intermediates of 2',2'-difluoronucleosides
ATE179713T1 (de) * 1987-08-28 1999-05-15 Lilly Co Eli Verfahren zur selektiven isolierung von beta-2'- desoxy-2'2'-difluorocytidin oder seiner salze

Also Published As

Publication number Publication date
KR940000473A (ko) 1994-01-03
US5256797A (en) 1993-10-26
HUT64551A (en) 1994-01-28
JPH0656867A (ja) 1994-03-01
CA2098888C (en) 2003-07-29
DE69308391T2 (de) 1997-07-17
KR100302087B1 (ko) 2001-10-22
EP0576232A1 (en) 1993-12-29
HU217976B (hu) 2000-05-28
CY2091B1 (en) 2002-04-05
CA2098888A1 (en) 1993-12-23
HK1006022A1 (en) 1999-02-05
MX9303714A (es) 1994-01-31
EP0576232B1 (en) 1997-03-05
DK0576232T3 (da) 1997-07-21
DE69308391D1 (de) 1997-04-10
HU9301826D0 (en) 1993-09-28
TW233300B (pt) 1994-11-01
ATE149505T1 (de) 1997-03-15
GR3023060T3 (en) 1997-07-30
IL106074A0 (en) 1993-10-20
ES2100462T3 (es) 1997-06-16
IL106074A (en) 1998-02-22

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Legal Events

Date Code Title Description
EE Request for examination
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal
CKFC Appeal: appeal against refusal