BR112022024382A2 - Formas sólidas de pralsetinibe - Google Patents
Formas sólidas de pralsetinibeInfo
- Publication number
- BR112022024382A2 BR112022024382A2 BR112022024382A BR112022024382A BR112022024382A2 BR 112022024382 A2 BR112022024382 A2 BR 112022024382A2 BR 112022024382 A BR112022024382 A BR 112022024382A BR 112022024382 A BR112022024382 A BR 112022024382A BR 112022024382 A2 BR112022024382 A2 BR 112022024382A2
- Authority
- BR
- Brazil
- Prior art keywords
- pralsetinib
- forms
- solid forms
- solid
- pyrazol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
FORMAS SÓLIDAS DE PRALSETINIBE. O composto cis)-N-((S)-1-(6-(4-fluoro-1H-pirazol-1-il)piridin-3-il)etil)-1-metoxi-4-(4-metil-6-(5-metil-1H-pirazol-3-ilamino)pirimidin-2-il)ciclo-hexanocarboxamida pode ser preparado como uma base livre em várias formas sólidas cristalinas e em várias formas de sal, cada uma tendo uma ou mais formas sólidas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063032121P | 2020-05-29 | 2020-05-29 | |
US202063047353P | 2020-07-02 | 2020-07-02 | |
PCT/US2021/034823 WO2021243192A1 (en) | 2020-05-29 | 2021-05-28 | Solid forms of pralsetinib |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022024382A2 true BR112022024382A2 (pt) | 2023-05-02 |
Family
ID=76601779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022024382A BR112022024382A2 (pt) | 2020-05-29 | 2021-05-28 | Formas sólidas de pralsetinibe |
Country Status (12)
Country | Link |
---|---|
US (1) | US20230295121A1 (pt) |
EP (1) | EP4157829A1 (pt) |
JP (1) | JP2023527412A (pt) |
KR (1) | KR20230017234A (pt) |
CN (1) | CN116075503A (pt) |
AU (1) | AU2021281365A1 (pt) |
BR (1) | BR112022024382A2 (pt) |
CA (1) | CA3183728A1 (pt) |
IL (1) | IL298523A (pt) |
MX (1) | MX2022014858A (pt) |
TW (1) | TW202210468A (pt) |
WO (1) | WO2021243192A1 (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HRP20240124T1 (hr) | 2018-04-03 | 2024-04-12 | Blueprint Medicines Corporation | Inhibitori za ret za uporabu u liječenju raka koji ima ret alteraciju |
US20230391746A1 (en) * | 2020-10-19 | 2023-12-07 | Teva Pharmaceuticals International Gmbh | Solid state forms of pralsetinib and process for preparation thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ742351A (en) | 2015-11-02 | 2023-03-31 | Blueprint Medicines Corp | Inhibitors of ret |
-
2021
- 2021-05-28 KR KR1020227044425A patent/KR20230017234A/ko active Search and Examination
- 2021-05-28 IL IL298523A patent/IL298523A/en unknown
- 2021-05-28 MX MX2022014858A patent/MX2022014858A/es unknown
- 2021-05-28 BR BR112022024382A patent/BR112022024382A2/pt unknown
- 2021-05-28 EP EP21734668.3A patent/EP4157829A1/en active Pending
- 2021-05-28 JP JP2022573208A patent/JP2023527412A/ja active Pending
- 2021-05-28 WO PCT/US2021/034823 patent/WO2021243192A1/en unknown
- 2021-05-28 CA CA3183728A patent/CA3183728A1/en active Pending
- 2021-05-28 CN CN202180059250.0A patent/CN116075503A/zh active Pending
- 2021-05-28 TW TW110119551A patent/TW202210468A/zh unknown
- 2021-05-28 AU AU2021281365A patent/AU2021281365A1/en active Pending
- 2021-05-28 US US18/000,168 patent/US20230295121A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2021243192A1 (en) | 2021-12-02 |
IL298523A (en) | 2023-01-01 |
TW202210468A (zh) | 2022-03-16 |
JP2023527412A (ja) | 2023-06-28 |
EP4157829A1 (en) | 2023-04-05 |
MX2022014858A (es) | 2023-02-23 |
CN116075503A (zh) | 2023-05-05 |
KR20230017234A (ko) | 2023-02-03 |
US20230295121A1 (en) | 2023-09-21 |
AU2021281365A1 (en) | 2022-12-15 |
CA3183728A1 (en) | 2021-12-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112022024382A2 (pt) | Formas sólidas de pralsetinibe | |
BR112022003375A2 (pt) | Compostos de pirazina-amida pesticidamente ativos | |
MX2020014165A (es) | Compuestos de azol-amida pesticidamente activos. | |
NO20074431L (no) | Pyrrolopyrimidiner nyttige som proteinkinaseinhibitorer | |
CO2021013183A2 (es) | Compuestos de diazina-amida activos como pesticidas | |
CO2021013350A2 (es) | Compuestos de diazina-amida activos como pesticidas | |
SG167664A1 (en) | 2,4-pyrimidinediamine compounds and their uses | |
EA200800201A1 (ru) | Кристаллические формы 4-метил-n-[3-(4-метилимидазол-1-ил)-5-трифторметилфенил]-3-(4-пиридин-3-илпиримидин-2-иламино)бензамида | |
HRP20041177B1 (hr) | Mikrobicidni pirimidini ili triazini za prevenciju prijenosa hiv seksualnim putem | |
ATE518010T1 (de) | Aktive oberflächengekoppelte polymerasen | |
CO2021012549A2 (es) | Compuestos de diazina-amida activos como pesticidas | |
EA200801406A1 (ru) | Антагонисты активина-actriia и их применение для стимулирования роста кости | |
ATE517896T1 (de) | P38-kinase-inhibitoren | |
NO20070699L (no) | Spesielle aminoalkylglukosaminidfosfatforbindelser og deres anvendelse | |
PE20200329A1 (es) | Procedimiento para establecer permisos de usuario en unidad de intercambio de informacion en el sistema | |
NO20072890L (no) | Behandling av mastitt | |
UY34191A (es) | ?N-(6-((2R,3S)-3,4-Dihidroxibutan-2-iloxi)-2-(4-fluorobenciltio)pirimidin-4-il)-3-metilazetidina-1-sulfonamida y sales farmacéuticamente aceptables de lamisma?. | |
BR112022004917A2 (pt) | Compostos de amina cíclica pesticidamente ativos | |
CY1112121T1 (el) | ΠΑΡΑΓΩΓΑ ΤΩΝ 1,2,3,4-ΤΕΤΡΑΫΔΡΟΠΥΡΡΟΛΟ-[1,2-α]-ΠΥΡΑΖΙΝ-6-ΚΑΡΒΟΞΑΜΙΔΙΩΝ ΚΑΙ ΤΩΝ 2,3,4,5-ΤΕΤΡΑΫΔΡΟΠΥΡΡΟΛΟ-(1,2-α)-ΔΙΑΖΕΠΙΝ-7-ΚΑΡΒΟΞΑΜΙΔΙΩΝ, Η ΠΑΡΑΣΚΕΥΗ ΤΟΥΣ ΚΑΙ Η ΕΦΑΡΜΟΓΗ ΤΟΥΣ ΣΕ ΘΕΡΑΠΕΥΤΙΚΗ ΑΓΩΓΗ | |
EA200601176A1 (ru) | 3-цианохинолиновые производные с антипролиферативной активностью | |
BRPI0518700B8 (pt) | combinação contendo vegf-trap, 5-fluorouracila e ácido folínico | |
BRPI0511125A (pt) | usos de ácido 5,6,7-triidroxieptanóico seus e análogos | |
SE0301654D0 (sv) | Novel compounds | |
BR0307286A (pt) | Tratamento de artrite reumatóide usando imatinib | |
PL420532A1 (pl) | Zastosowanie 3-(4-bromofenetylo)-6-(tert-butylo)-3,4-dihydro-2H-benzo[1,3]oksazyny |