BR112022019434A2 - Peptídeo que tem atividade de mobilização de células-tronco mesenquimais - Google Patents
Peptídeo que tem atividade de mobilização de células-tronco mesenquimaisInfo
- Publication number
- BR112022019434A2 BR112022019434A2 BR112022019434A BR112022019434A BR112022019434A2 BR 112022019434 A2 BR112022019434 A2 BR 112022019434A2 BR 112022019434 A BR112022019434 A BR 112022019434A BR 112022019434 A BR112022019434 A BR 112022019434A BR 112022019434 A2 BR112022019434 A2 BR 112022019434A2
- Authority
- BR
- Brazil
- Prior art keywords
- peptide
- mesenchymal stem
- stem cell
- cell mobilization
- activity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PEPTÍDEO QUE TEM ATIVIDADE DE MOBILIZAÇÃO DE CÉLULAS-TRONCO MESENQUIMAIS. A presente invenção refere-se a uma pluralidade de peptídeos, cada um consistindo em uma sequência parcial do peptídeo de sequência artificial "1r10" (fragmentos do peptídeo 1r10), o qual foi descoberto a partir de suas próprias pesquisas realizadas até o momento, investigaram se eles têm uma atividade de mobilização de células-tronco mesenquimais no sangue periférico e, como um resultado, descobriram que um fragmento do peptídeo 1r10 que tem uma sequência de aminoácidos específica mostra a atividade. Com base nesta descoberta, é fornecido um peptídeo que se acredita apresentar efeitos terapêuticos em várias doenças por meio de mobilização de células-tronco mesenquimais no sangue periférico.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2020067570 | 2020-04-03 | ||
PCT/JP2021/014253 WO2021201260A1 (ja) | 2020-04-03 | 2021-04-02 | 間葉系幹細胞の動員活性を有するペプチド |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022019434A2 true BR112022019434A2 (pt) | 2022-12-06 |
Family
ID=77929177
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022019434A BR112022019434A2 (pt) | 2020-04-03 | 2021-04-02 | Peptídeo que tem atividade de mobilização de células-tronco mesenquimais |
Country Status (8)
Country | Link |
---|---|
US (1) | US20230241159A1 (pt) |
EP (1) | EP4144359A4 (pt) |
JP (1) | JPWO2021201260A1 (pt) |
CN (1) | CN115697372A (pt) |
BR (1) | BR112022019434A2 (pt) |
CA (1) | CA3178719A1 (pt) |
IL (1) | IL296982A (pt) |
WO (1) | WO2021201260A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3051825A1 (en) | 2017-01-27 | 2018-08-02 | StemRIM Inc. | Therapeutic agent for cardiomyopathy, old myocardial infarction and chronic heart failure |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2519714C2 (ru) * | 2008-04-30 | 2014-06-20 | Дженомикс Ко., Лтд. | Средство для вовлечения происходящей из костного мозга плюрипотентной стволовой клетки в периферический кровоток |
KR20120135190A (ko) * | 2009-10-28 | 2012-12-12 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 골수 간엽계 및/또는 다능성 줄기세포의 혈중 동원(動員)에 의한 조직 재생 촉진제 |
EP2703487B1 (en) * | 2011-04-26 | 2018-06-27 | Genomix Co., Ltd. | Peptide for inducing regeneration of tissue and use thereof |
US20200038486A1 (en) * | 2017-04-07 | 2020-02-06 | StemRIM Inc. | Therapeutic medicine for fibrous disease |
MX2019012738A (es) * | 2017-04-25 | 2020-02-07 | Shionogi & Co | Peptido para inducir la regeneracion de tejido, y uso del mismo. |
US11298403B2 (en) * | 2017-12-01 | 2022-04-12 | StemRIM Inc. | Therapeutic agent for inflammatory bowel disease |
US20220009976A1 (en) * | 2018-10-05 | 2022-01-13 | StemRIM Inc. | Peptide Possessing Mesenchymal-Stem-Cell Mobilizing Activity |
WO2020158924A1 (ja) * | 2019-01-31 | 2020-08-06 | 国立大学法人大阪大学 | 母児間免疫寛容を誘導する方法 |
-
2021
- 2021-04-02 JP JP2022511147A patent/JPWO2021201260A1/ja active Pending
- 2021-04-02 BR BR112022019434A patent/BR112022019434A2/pt unknown
- 2021-04-02 WO PCT/JP2021/014253 patent/WO2021201260A1/ja active Application Filing
- 2021-04-02 EP EP21781212.2A patent/EP4144359A4/en active Pending
- 2021-04-02 IL IL296982A patent/IL296982A/en unknown
- 2021-04-02 CA CA3178719A patent/CA3178719A1/en active Pending
- 2021-04-02 US US17/995,017 patent/US20230241159A1/en active Pending
- 2021-04-02 CN CN202180032617.XA patent/CN115697372A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
IL296982A (en) | 2022-12-01 |
CA3178719A1 (en) | 2021-10-07 |
WO2021201260A1 (ja) | 2021-10-07 |
CN115697372A (zh) | 2023-02-03 |
EP4144359A1 (en) | 2023-03-08 |
EP4144359A4 (en) | 2024-05-01 |
JPWO2021201260A1 (pt) | 2021-10-07 |
US20230241159A1 (en) | 2023-08-03 |
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