BR112022012409A2 - Matrizes para entregar campos de tratamento de tumor (ttfields) com elementos de eletrodo acessíveis individualmente e sensores de temperatura - Google Patents

Matrizes para entregar campos de tratamento de tumor (ttfields) com elementos de eletrodo acessíveis individualmente e sensores de temperatura

Info

Publication number
BR112022012409A2
BR112022012409A2 BR112022012409A BR112022012409A BR112022012409A2 BR 112022012409 A2 BR112022012409 A2 BR 112022012409A2 BR 112022012409 A BR112022012409 A BR 112022012409A BR 112022012409 A BR112022012409 A BR 112022012409A BR 112022012409 A2 BR112022012409 A2 BR 112022012409A2
Authority
BR
Brazil
Prior art keywords
ttfields
electrode elements
tumor treatment
matrices
treatment fields
Prior art date
Application number
BR112022012409A
Other languages
English (en)
Inventor
Wasserman Yoram
Original Assignee
Novocure Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novocure Gmbh filed Critical Novocure Gmbh
Publication of BR112022012409A2 publication Critical patent/BR112022012409A2/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36002Cancer treatment, e.g. tumour
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0476Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/3603Control systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/3603Control systems
    • A61N1/36031Control systems using physiological parameters for adjustment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A61N1/403Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00059Material properties
    • A61B2018/00071Electrical conductivity
    • A61B2018/00077Electrical conductivity high, i.e. electrically conducting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/0016Energy applicators arranged in a two- or three dimensional array
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00172Connectors and adapters therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00666Sensing and controlling the application of energy using a threshold value
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00791Temperature
    • A61B2018/00815Temperature measured by a thermistor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/0091Handpieces of the surgical instrument or device
    • A61B2018/00916Handpieces of the surgical instrument or device with means for switching or controlling the main function of the instrument or device
    • A61B2018/00922Handpieces of the surgical instrument or device with means for switching or controlling the main function of the instrument or device by switching or controlling the treatment energy directly within the hand-piece
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0492Patch electrodes
    • A61N1/0496Patch electrodes characterised by using specific chemical compositions, e.g. hydrogel compositions, adhesives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physiology (AREA)
  • Surgery (AREA)
  • Otolaryngology (AREA)
  • Plasma & Fusion (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Electrotherapy Devices (AREA)

Abstract

MATRIZES PARA ENTREGAR CAMPOS DE TRATAMENTO DE TUMOR (TTFIELDS) COM ELEMENTOS DE ELETRODO ACESSÍVEIS INDIVIDUALMENTE E SENSORES DE TEMPERATURA. Campos de tratamento de tumor (TTFields) podem ser entregues a um corpo do sujeito em intensidades de campo mais altas desligando um ou mais elementos de eletrodo em uma matriz de transdutor que estão superaquecendo. Isso pode ser realizado usando termistores que detectam a temperatura de cada elemento de eletrodo. Porções da fiação de cada matriz de transdutor são compartilhadas entre os elementos de eletrodo e os termistores usando uma pluralidade de condutores, cada um dos quais conecta eletricamente (a) um pino de um conector, (b) um respectivo elemento de eletrodo, e (c) um respectivo termistor. Em algumas modalidades, todos os termistores são ligados em série. Em outras modalidades, todos os termistores compartilham uma conexão comum.
BR112022012409A 2019-12-31 2020-12-21 Matrizes para entregar campos de tratamento de tumor (ttfields) com elementos de eletrodo acessíveis individualmente e sensores de temperatura BR112022012409A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962955664P 2019-12-31 2019-12-31
PCT/IB2020/062309 WO2021137094A1 (en) 2019-12-31 2020-12-21 Arrays for delivering tumor treating fields (ttfields) with individually accessible electrode elements and temperature sensors

Publications (1)

Publication Number Publication Date
BR112022012409A2 true BR112022012409A2 (pt) 2022-08-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022012409A BR112022012409A2 (pt) 2019-12-31 2020-12-21 Matrizes para entregar campos de tratamento de tumor (ttfields) com elementos de eletrodo acessíveis individualmente e sensores de temperatura

Country Status (17)

Country Link
US (2) US11878163B2 (pt)
EP (3) EP4212203A1 (pt)
JP (1) JP2023508585A (pt)
KR (1) KR20220123079A (pt)
CN (1) CN114901344A (pt)
AU (1) AU2020416669A1 (pt)
BR (1) BR112022012409A2 (pt)
CA (1) CA3163316A1 (pt)
DK (1) DK4074367T3 (pt)
ES (1) ES2950234T3 (pt)
FI (1) FI4074367T3 (pt)
HU (1) HUE061733T2 (pt)
IL (1) IL294386A (pt)
MX (1) MX2022006136A (pt)
PL (1) PL4074367T3 (pt)
TW (1) TW202138023A (pt)
WO (1) WO2021137094A1 (pt)

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DK4074367T3 (da) 2023-05-22
EP4212203A1 (en) 2023-07-19
PL4074367T3 (pl) 2023-07-31
WO2021137094A1 (en) 2021-07-08
CN114901344A (zh) 2022-08-12
KR20220123079A (ko) 2022-09-05
CA3163316A1 (en) 2021-07-08
US11878163B2 (en) 2024-01-23
IL294386A (en) 2022-08-01
HUE061733T2 (hu) 2023-08-28
EP4074367B1 (en) 2023-04-19
US20240139505A1 (en) 2024-05-02
TW202138023A (zh) 2021-10-16
EP4054701A1 (en) 2022-09-14
FI4074367T3 (fi) 2023-06-21
MX2022006136A (es) 2022-06-17
ES2950234T3 (es) 2023-10-06
EP4074367A1 (en) 2022-10-19
AU2020416669A1 (en) 2022-06-16
JP2023508585A (ja) 2023-03-02
US20210196348A1 (en) 2021-07-01

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