BR112022009072A2 - Processo de realização de uma reação bioquímica, macromolécula idr, polipeptídeo idr, molécula de ácido nucleico isolada, vetor de expressão de polinucleotídeo recombinante, célula hospedeira, cultura celular, kit, processo para estimular ou melhorar a desmistura líquido-líquido, uso de íons de metais multivalentes, método para determinar a sequência nucleotídica e uso de uma macromolécula idr ou um polipeptídeo idr - Google Patents
Processo de realização de uma reação bioquímica, macromolécula idr, polipeptídeo idr, molécula de ácido nucleico isolada, vetor de expressão de polinucleotídeo recombinante, célula hospedeira, cultura celular, kit, processo para estimular ou melhorar a desmistura líquido-líquido, uso de íons de metais multivalentes, método para determinar a sequência nucleotídica e uso de uma macromolécula idr ou um polipeptídeo idrInfo
- Publication number
- BR112022009072A2 BR112022009072A2 BR112022009072A BR112022009072A BR112022009072A2 BR 112022009072 A2 BR112022009072 A2 BR 112022009072A2 BR 112022009072 A BR112022009072 A BR 112022009072A BR 112022009072 A BR112022009072 A BR 112022009072A BR 112022009072 A2 BR112022009072 A2 BR 112022009072A2
- Authority
- BR
- Brazil
- Prior art keywords
- idr
- liquid
- polypeptide
- macromolecule
- macromolecules
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/50—Other enzymatic activities
- C12Q2521/507—Recombinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2522/00—Reaction characterised by the use of non-enzymatic proteins
- C12Q2522/10—Nucleic acid binding proteins
- C12Q2522/101—Single or double stranded nucleic acid binding proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/125—Specific component of sample, medium or buffer
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1916379.9A GB201916379D0 (en) | 2019-11-11 | 2019-11-11 | Biochemical reaction methods and reagents |
| PCT/GB2020/052866 WO2021094746A1 (en) | 2019-11-11 | 2020-11-11 | Biochemical reaction methods and reagents comprising intrinsically disordered regions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022009072A2 true BR112022009072A2 (pt) | 2022-07-26 |
Family
ID=69062276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022009072A BR112022009072A2 (pt) | 2019-11-11 | 2020-11-11 | Processo de realização de uma reação bioquímica, macromolécula idr, polipeptídeo idr, molécula de ácido nucleico isolada, vetor de expressão de polinucleotídeo recombinante, célula hospedeira, cultura celular, kit, processo para estimular ou melhorar a desmistura líquido-líquido, uso de íons de metais multivalentes, método para determinar a sequência nucleotídica e uso de uma macromolécula idr ou um polipeptídeo idr |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11807899B2 (https=) |
| EP (1) | EP4058599A1 (https=) |
| JP (2) | JP7840266B2 (https=) |
| KR (1) | KR20220113948A (https=) |
| CN (1) | CN114945682A (https=) |
| AU (1) | AU2020382121A1 (https=) |
| BR (1) | BR112022009072A2 (https=) |
| CA (1) | CA3157435A1 (https=) |
| GB (1) | GB201916379D0 (https=) |
| IL (1) | IL292885A (https=) |
| MX (1) | MX2022005677A (https=) |
| WO (1) | WO2021094746A1 (https=) |
| ZA (1) | ZA202205093B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108998406B (zh) * | 2018-08-03 | 2022-05-10 | 福州大学 | 一种人类原代培养细胞基因组编辑、定点基因敲入方法 |
| CN113355389B (zh) * | 2020-03-05 | 2022-11-15 | 广西扬翔股份有限公司 | 利用CRISPR/Cas12a系统靶向富集核酸目标区域的方法及其应用 |
| US20240110221A1 (en) * | 2022-09-30 | 2024-04-04 | Illumina, Inc. | Methods of modulating clustering kinetics |
| CN116251621B (zh) * | 2022-12-13 | 2024-08-23 | 中国科学院基础医学与肿瘤研究所(筹) | 一种提高氯化血红素的过氧化物酶活性的方法 |
| WO2024178628A1 (en) * | 2023-02-28 | 2024-09-06 | Sun Yat-Sen University | Epigenetic editor assisted by phase separation proteins |
| JP2024179837A (ja) * | 2023-06-16 | 2024-12-26 | 国立大学法人 東京大学 | 酵素の検出方法及び酵素の検出キット |
| KR20250022285A (ko) | 2023-08-07 | 2025-02-17 | 포항공과대학교 산학협력단 | 액체-액체 상분리를 통한 scotin 프롤린-풍부 도메인 생체분자 응축물 및 그의 응용 |
| GB2643378A (en) * | 2024-07-15 | 2026-02-18 | Biocrucible Ltd | Reagents and methods |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| US7270981B2 (en) | 2002-02-21 | 2007-09-18 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| WO2005103670A1 (ja) | 2004-04-21 | 2005-11-03 | Toray Industries, Inc. | ラボオンチップ用基板 |
| DE102005052752A1 (de) | 2005-11-04 | 2007-05-10 | Clondiag Chip Technologies Gmbh | Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen |
| WO2007096702A2 (en) | 2005-07-25 | 2007-08-30 | Asm Scientific, Inc. | Methods for multiplexing recombinase polymerase amplification |
| US20070059713A1 (en) * | 2005-09-09 | 2007-03-15 | Lee Jun E | SSB-DNA polymerase fusion proteins |
| US8071308B2 (en) * | 2006-05-04 | 2011-12-06 | Alere San Diego, Inc. | Recombinase polymerase amplification |
| WO2008108927A2 (en) * | 2007-03-06 | 2008-09-12 | Regenerx Biopharmaceuticals, Inc. | Methods and compositions for stabilizing polypeptides |
| CN101743063B (zh) | 2007-05-03 | 2012-12-12 | 科隆迪亚戈有限公司 | 分析方法 |
| US8560130B2 (en) | 2007-12-04 | 2013-10-15 | Lester F. Ludwig | Software controlled lab-on-a-chip emulation |
| CN108088824B (zh) | 2008-03-14 | 2021-06-04 | 雅培快速诊断耶拿有限公司 | 一种用于检测分析物的系统 |
| EP2438196B1 (en) | 2009-06-05 | 2016-12-21 | Alere San Diego, Inc. | Recombinase polymerase amplification reagents and kits |
| SG179200A1 (en) * | 2009-09-16 | 2012-04-27 | Univ Massey | Fusion polypeptides and uses thereof |
| WO2013154898A1 (en) * | 2012-04-12 | 2013-10-17 | Ong, Jennifer | Synthetic nucleic acids for polymerization reactions |
| US10533167B2 (en) * | 2016-06-09 | 2020-01-14 | The Trustees Of Princeton University | Optogenetic tool for rapid and reversible clustering of proteins |
| WO2018100408A1 (en) * | 2016-11-30 | 2018-06-07 | Sasinapas Co.,Ltd. | Modified peptides |
| US20210047659A1 (en) * | 2018-01-24 | 2021-02-18 | The Trustees Of Princeton University | System and method for inducing clusters of gene regulatory proteins targeted to specific genomic loci |
-
2019
- 2019-11-11 GB GBGB1916379.9A patent/GB201916379D0/en not_active Ceased
-
2020
- 2020-11-11 CN CN202080092644.1A patent/CN114945682A/zh active Pending
- 2020-11-11 JP JP2022553222A patent/JP7840266B2/ja active Active
- 2020-11-11 WO PCT/GB2020/052866 patent/WO2021094746A1/en not_active Ceased
- 2020-11-11 KR KR1020227019839A patent/KR20220113948A/ko active Pending
- 2020-11-11 AU AU2020382121A patent/AU2020382121A1/en active Pending
- 2020-11-11 MX MX2022005677A patent/MX2022005677A/es unknown
- 2020-11-11 IL IL292885A patent/IL292885A/en unknown
- 2020-11-11 BR BR112022009072A patent/BR112022009072A2/pt not_active IP Right Cessation
- 2020-11-11 EP EP20817468.0A patent/EP4058599A1/en active Pending
- 2020-11-11 CA CA3157435A patent/CA3157435A1/en active Pending
-
2021
- 2021-11-19 US US17/531,349 patent/US11807899B2/en active Active
-
2022
- 2022-05-09 ZA ZA2022/05093A patent/ZA202205093B/en unknown
-
2025
- 2025-11-28 JP JP2025207502A patent/JP2026041819A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN114945682A (zh) | 2022-08-26 |
| AU2020382121A8 (en) | 2022-07-28 |
| GB201916379D0 (en) | 2019-12-25 |
| US11807899B2 (en) | 2023-11-07 |
| US20220112547A1 (en) | 2022-04-14 |
| CA3157435A1 (en) | 2021-05-20 |
| WO2021094746A1 (en) | 2021-05-20 |
| AU2020382121A1 (en) | 2022-06-16 |
| JP2023501002A (ja) | 2023-01-17 |
| JP2026041819A (ja) | 2026-03-10 |
| JP7840266B2 (ja) | 2026-04-03 |
| MX2022005677A (es) | 2022-09-07 |
| ZA202205093B (en) | 2024-10-30 |
| US20220145378A1 (en) | 2022-05-12 |
| EP4058599A1 (en) | 2022-09-21 |
| IL292885A (en) | 2022-07-01 |
| KR20220113948A (ko) | 2022-08-17 |
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Legal Events
| Date | Code | Title | Description |
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| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A ANUIDADE. |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2853 DE 09-09-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |