BR112021026805A2 - Bloqueio neural por estimulação elétrica de baixa frequência de super limiar - Google Patents

Bloqueio neural por estimulação elétrica de baixa frequência de super limiar

Info

Publication number
BR112021026805A2
BR112021026805A2 BR112021026805A BR112021026805A BR112021026805A2 BR 112021026805 A2 BR112021026805 A2 BR 112021026805A2 BR 112021026805 A BR112021026805 A BR 112021026805A BR 112021026805 A BR112021026805 A BR 112021026805A BR 112021026805 A2 BR112021026805 A2 BR 112021026805A2
Authority
BR
Brazil
Prior art keywords
electrical stimulation
super
frequency electrical
neuron
threshold low
Prior art date
Application number
BR112021026805A
Other languages
English (en)
Portuguese (pt)
Inventor
Changfeng Tai
Original Assignee
Univ Pittsburgh Commonwealth Sys Higher Education
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh Commonwealth Sys Higher Education filed Critical Univ Pittsburgh Commonwealth Sys Higher Education
Publication of BR112021026805A2 publication Critical patent/BR112021026805A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36034—Control systems specified by the stimulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36062—Spinal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071—Pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A61N1/36153—Voltage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A61N1/36157—Current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36171—Frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36178—Burst or pulse train parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Electrotherapy Devices (AREA)
BR112021026805A 2019-07-03 2020-06-30 Bloqueio neural por estimulação elétrica de baixa frequência de super limiar BR112021026805A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962870230P 2019-07-03 2019-07-03
PCT/US2020/040288 WO2021003151A1 (en) 2019-07-03 2020-06-30 Neural block by super-threshold low frequency electrical stimulation

Publications (1)

Publication Number Publication Date
BR112021026805A2 true BR112021026805A2 (pt) 2022-02-15

Family

ID=74101293

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021026805A BR112021026805A2 (pt) 2019-07-03 2020-06-30 Bloqueio neural por estimulação elétrica de baixa frequência de super limiar

Country Status (9)

Country Link
US (1) US20220395686A1 (enExample)
EP (1) EP3993865A4 (enExample)
JP (1) JP7609359B2 (enExample)
KR (1) KR102944729B1 (enExample)
CN (1) CN114286705A (enExample)
AU (1) AU2020300506B2 (enExample)
BR (1) BR112021026805A2 (enExample)
CA (1) CA3145807A1 (enExample)
WO (1) WO2021003151A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11413458B2 (en) 2011-05-19 2022-08-16 Neuros Medical, Inc. Nerve cuff electrode for neuromodulation in large human nerve trunks
US11878172B2 (en) 2020-02-11 2024-01-23 Neuros Medical, Inc. System and method for quantifying qualitative patient-reported data sets
IL305807A (en) 2021-03-12 2023-11-01 Amber Therapeutics Ltd Systems for controlling urinary incontinence
WO2023064029A1 (en) * 2021-10-14 2023-04-20 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Sacral neuromodulation for bowel and sexual functions

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8626302B2 (en) * 1998-06-03 2014-01-07 Spr Therapeutics, Llc Systems and methods to place one or more leads in muscle for providing electrical stimulation to treat pain
US6393323B1 (en) * 2000-01-31 2002-05-21 Mcgill University Electronic stimulator implant for modulating and synchronizing bladder and sphincter function
US6928320B2 (en) * 2001-05-17 2005-08-09 Medtronic, Inc. Apparatus for blocking activation of tissue or conduction of action potentials while other tissue is being therapeutically activated
US7328069B2 (en) * 2002-09-06 2008-02-05 Medtronic, Inc. Method, system and device for treating disorders of the pelvic floor by electrical stimulation of and the delivery of drugs to the left and right pudendal nerves
US20050070970A1 (en) * 2003-09-29 2005-03-31 Knudson Mark B. Movement disorder stimulation with neural block
EP1706178B1 (en) * 2004-01-22 2013-04-24 Rehabtronics Inc. System for routing electrical current to bodily tissues via implanted passive conductors
US20070073354A1 (en) * 2005-09-26 2007-03-29 Knudson Mark B Neural blocking therapy
US9020597B2 (en) * 2008-11-12 2015-04-28 Endostim, Inc. Device and implantation system for electrical stimulation of biological systems
WO2009018518A1 (en) * 2007-08-02 2009-02-05 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Methods and systems for achieving a physiological response by pudendal nerve stimulation and bockade
US8195287B2 (en) * 2007-12-05 2012-06-05 The Invention Science Fund I, Llc Method for electrical modulation of neural conduction
US20090254144A1 (en) 2008-04-02 2009-10-08 Case Western Reserve University System and Method of Bladder and Sphincter Control
WO2010067360A2 (en) * 2008-12-09 2010-06-17 Nephera Ltd. Stimulation of the urinary system
US9174045B2 (en) * 2009-03-20 2015-11-03 ElectroCore, LLC Non-invasive electrical and magnetic nerve stimulators used to treat overactive bladder and urinary incontinence
US10195434B2 (en) * 2012-06-15 2019-02-05 Case Western Reserve University Treatment of pain using electrical nerve conduction block
US9511230B2 (en) * 2013-11-08 2016-12-06 Nuvectra Corporation Implantable medical lead for stimulation of multiple nerves
WO2015109023A1 (en) 2014-01-17 2015-07-23 Cardiac Pacemakers, Inc. Depletion block to block nerve communication
CN106794347B (zh) 2014-05-23 2020-01-17 电核有限责任公司 用于迷走神经刺激的系统和方法
AU2014405934B2 (en) * 2014-09-12 2020-05-07 Neuros Medical, Inc Nerve cuff electrode for neuromodulation in large human nerve trunks
CN105310680B (zh) * 2015-05-14 2018-03-27 南京神桥医疗器械有限公司 一种植入式神经信号阻断装置
JP7013023B2 (ja) * 2015-05-21 2022-01-31 イービーティー メディカル，インコーポレイテッド 膀胱機能障害の治療のためのシステム及び方法
CA2994509A1 (en) 2015-08-03 2017-02-09 Galvani Bioelectronics Limited Neuromodulation device
CN106621032A (zh) * 2015-10-28 2017-05-10 精能医学股份有限公司 电刺激器及应用其的刺激方法及电刺激系统
AU2016364743B2 (en) * 2015-12-03 2021-08-12 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Device and method for nerve block by local cooling to room temperature
JP2019502527A (ja) 2016-01-19 2019-01-31 インキューブ ラブズ， エルエルシー 患者に可能な膀胱制御のためのシステムおよび方法
WO2017210433A1 (en) * 2016-06-02 2017-12-07 Boston Scientific Neuromodulation Corporation Priming-assisted neuromodulation therapy
WO2017210672A1 (en) * 2016-06-03 2017-12-07 The Cleveland Clinic Foundation Systems and methods for monitoring a depth of neuromuscular blockade
WO2018033111A1 (en) * 2016-08-17 2018-02-22 Tam Pui Ling Non-invasive device and method for stimulating vulvar tissues and pelvic floor muscles for treating and improving dysfunction or disorders and probe unit used therefor
CN109862937A (zh) * 2016-08-25 2019-06-07 维兰德.K.沙马 用于电刺激肛门直肠结构以治疗泌尿功能障碍的系统和方法

Also Published As

Publication number Publication date
CA3145807A1 (en) 2021-01-07
JP7609359B2 (ja) 2025-01-07
KR20220035140A (ko) 2022-03-21
KR102944729B1 (ko) 2026-03-30
AU2020300506A1 (en) 2022-01-27
WO2021003151A1 (en) 2021-01-07
US20220395686A1 (en) 2022-12-15
AU2020300506B2 (en) 2025-09-04
EP3993865A4 (en) 2023-07-19
CN114286705A (zh) 2022-04-05
EP3993865A1 (en) 2022-05-11
JP2022539172A (ja) 2022-09-07

Similar Documents

Publication Publication Date Title
BR112021016620A2 (pt) Azepino-indóis e outros heterociclos para o tratamento de distúrbios cerebrais
CO2021008018A2 (es) Composiciones y métodos para modular la actividad de deshidrogenasas de cadena corta
CY1124328T1 (el) Δραστικος και αποτελεσματικος ελεγχος tων φωσφορικων ορου για τον βελτιστο σχηματισμο των οστων
MX2021013197A (es) Cicloalquilos sustituidos como moduladores de la vía integrada del estrés.
CY1125539T1 (el) Παραγωγα αζετιδινης ως ρυθμιστες του υποδοχεα χημειοκινης και χρηση αυτων
MX2020008906A (es) Compuestos con actividad inductora de ferroptosis y métodos de uso de estos.
AU2017232365A8 (en) Microcurrent device and method for the treatment of visual disease
MX2022003193A (es) Tratamiento de encefalopatia asociada al gen syngap1.
BR112018013522A2 (pt) compostos inibidores de metaloenzima
BR112022013554A2 (pt) Métodos para tratar distúrbios do pênfigo
MX387580B (es) Sistema de gestión de modulación de fotones para la estimulación de una respuesta deseada en aves.
BR112017021312A2 (pt) tratamento de câncer de pulmão com inibidores de glutaminase
BR112021024634A2 (pt) Método de tratamento ou prevenção de um distúrbio, doença ou condição aliviada pela estimulação ou modulação da expressão de colágeno
EP4085919A3 (en) Compositions and methods to treat cancer
BR112017009053A2 (pt) dispositivo para inibição da atividade neural de um nervo do seio carotídeo ou corpo carotídeo, método para tratamento de uma condição, forma de onda elétrica neuromodulatória, e, uso de um dispositivo de neuromodulação para o tratamento de uma condição.
WO2015066679A3 (en) Treatment of central nervous system conditions using sensory stimulus
MX2022004270A (es) Inhibidores de aldosa reductasa para el tratamiento de la deficiencia de fosfomannomutasa 2.
CL2021002318A1 (es) Métodos de tratamiento de amiloidosis al
MX2021003450A (es) Metodos para tratar trastornos mieloproliferativos.
CO2022001354A2 (es) Métodos para tratar o prevenir la atrofia muscular espinal
MX2020010634A (es) Metodo para la produccion de cetoenoles ciclicos sustituidos por espirocetal.
CO2018011633A2 (es) 6-aminopiridin-3-il tiazoles como moduladores de rorγt
IL291582A (en) Therapeutic window for treatment of ischemia by vagus nerve stimulation
KR102356607B9 (ko) 환자의 신경에 전기적인 자극을 가하여 신경을 조절하는 장치, 방법 및 프로그램
WO2016151570A9 (en) System and method for tissue whitening by applying electromagnetic field

Legal Events

Date Code Title Description
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]