KR102944729B1 - 초역치 저주파 전기 자극에 의한 신경 차단 - Google Patents

초역치 저주파 전기 자극에 의한 신경 차단

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Publication number
KR102944729B1
KR102944729B1 KR1020227002367A KR20227002367A KR102944729B1 KR 102944729 B1 KR102944729 B1 KR 102944729B1 KR 1020227002367 A KR1020227002367 A KR 1020227002367A KR 20227002367 A KR20227002367 A KR 20227002367A KR 102944729 B1 KR102944729 B1 KR 102944729B1
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KR
South Korea
Prior art keywords
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nerve
minutes
stimulation
intensity
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Application number
KR1020227002367A
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English (en)
Korean (ko)
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KR20220035140A (ko
Inventor
창펑 타이
Original Assignee
유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션
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Publication of KR20220035140A publication Critical patent/KR20220035140A/ko
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36034—Control systems specified by the stimulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36062—Spinal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071—Pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A61N1/36153—Voltage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A61N1/36157—Current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36171—Frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36178—Burst or pulse train parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Electrotherapy Devices (AREA)
KR1020227002367A 2019-07-03 2020-06-30 초역치 저주파 전기 자극에 의한 신경 차단 Active KR102944729B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962870230P 2019-07-03 2019-07-03
US62/870,230 2019-07-03
PCT/US2020/040288 WO2021003151A1 (en) 2019-07-03 2020-06-30 Neural block by super-threshold low frequency electrical stimulation

Publications (2)

Publication Number Publication Date
KR20220035140A KR20220035140A (ko) 2022-03-21
KR102944729B1 true KR102944729B1 (ko) 2026-03-30

Family

ID=74101293

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227002367A Active KR102944729B1 (ko) 2019-07-03 2020-06-30 초역치 저주파 전기 자극에 의한 신경 차단

Country Status (9)

Country Link
US (1) US20220395686A1 (enExample)
EP (1) EP3993865A4 (enExample)
JP (1) JP7609359B2 (enExample)
KR (1) KR102944729B1 (enExample)
CN (1) CN114286705A (enExample)
AU (1) AU2020300506B2 (enExample)
BR (1) BR112021026805A2 (enExample)
CA (1) CA3145807A1 (enExample)
WO (1) WO2021003151A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11413458B2 (en) 2011-05-19 2022-08-16 Neuros Medical, Inc. Nerve cuff electrode for neuromodulation in large human nerve trunks
US11878172B2 (en) 2020-02-11 2024-01-23 Neuros Medical, Inc. System and method for quantifying qualitative patient-reported data sets
IL305807A (en) 2021-03-12 2023-11-01 Amber Therapeutics Ltd Systems for controlling urinary incontinence
WO2023064029A1 (en) * 2021-10-14 2023-04-20 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Sacral neuromodulation for bowel and sexual functions

Citations (3)

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US20060184211A1 (en) 2004-01-22 2006-08-17 Gaunt Robert A Method of routing electrical current to bodily tissues via implanted passive conductors
JP2017502786A (ja) 2014-01-17 2017-01-26 カーディアック ペースメイカーズ， インコーポレイテッド 神経連絡をブロックする枯渇ブロック
US20170182319A1 (en) * 2007-08-02 2017-06-29 University Of Pittsburgh - Of The Commonwealth System Of Higher Education "Methods and Systems for Achieving a Physiological Response by Pudendal Nerve Stimulation and Blockade"

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US8626302B2 (en) * 1998-06-03 2014-01-07 Spr Therapeutics, Llc Systems and methods to place one or more leads in muscle for providing electrical stimulation to treat pain
US6393323B1 (en) * 2000-01-31 2002-05-21 Mcgill University Electronic stimulator implant for modulating and synchronizing bladder and sphincter function
US6928320B2 (en) * 2001-05-17 2005-08-09 Medtronic, Inc. Apparatus for blocking activation of tissue or conduction of action potentials while other tissue is being therapeutically activated
US7328069B2 (en) * 2002-09-06 2008-02-05 Medtronic, Inc. Method, system and device for treating disorders of the pelvic floor by electrical stimulation of and the delivery of drugs to the left and right pudendal nerves
US20050070970A1 (en) * 2003-09-29 2005-03-31 Knudson Mark B. Movement disorder stimulation with neural block
US20070073354A1 (en) * 2005-09-26 2007-03-29 Knudson Mark B Neural blocking therapy
US9020597B2 (en) * 2008-11-12 2015-04-28 Endostim, Inc. Device and implantation system for electrical stimulation of biological systems
US8195287B2 (en) * 2007-12-05 2012-06-05 The Invention Science Fund I, Llc Method for electrical modulation of neural conduction
US20090254144A1 (en) 2008-04-02 2009-10-08 Case Western Reserve University System and Method of Bladder and Sphincter Control
WO2010067360A2 (en) * 2008-12-09 2010-06-17 Nephera Ltd. Stimulation of the urinary system
US9174045B2 (en) * 2009-03-20 2015-11-03 ElectroCore, LLC Non-invasive electrical and magnetic nerve stimulators used to treat overactive bladder and urinary incontinence
US10195434B2 (en) * 2012-06-15 2019-02-05 Case Western Reserve University Treatment of pain using electrical nerve conduction block
US9511230B2 (en) * 2013-11-08 2016-12-06 Nuvectra Corporation Implantable medical lead for stimulation of multiple nerves
CN106794347B (zh) 2014-05-23 2020-01-17 电核有限责任公司 用于迷走神经刺激的系统和方法
AU2014405934B2 (en) * 2014-09-12 2020-05-07 Neuros Medical, Inc Nerve cuff electrode for neuromodulation in large human nerve trunks
CN105310680B (zh) * 2015-05-14 2018-03-27 南京神桥医疗器械有限公司 一种植入式神经信号阻断装置
JP7013023B2 (ja) * 2015-05-21 2022-01-31 イービーティー メディカル，インコーポレイテッド 膀胱機能障害の治療のためのシステム及び方法
CA2994509A1 (en) 2015-08-03 2017-02-09 Galvani Bioelectronics Limited Neuromodulation device
CN106621032A (zh) * 2015-10-28 2017-05-10 精能医学股份有限公司 电刺激器及应用其的刺激方法及电刺激系统
AU2016364743B2 (en) * 2015-12-03 2021-08-12 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Device and method for nerve block by local cooling to room temperature
JP2019502527A (ja) 2016-01-19 2019-01-31 インキューブ ラブズ， エルエルシー 患者に可能な膀胱制御のためのシステムおよび方法
WO2017210433A1 (en) * 2016-06-02 2017-12-07 Boston Scientific Neuromodulation Corporation Priming-assisted neuromodulation therapy
WO2017210672A1 (en) * 2016-06-03 2017-12-07 The Cleveland Clinic Foundation Systems and methods for monitoring a depth of neuromuscular blockade
WO2018033111A1 (en) * 2016-08-17 2018-02-22 Tam Pui Ling Non-invasive device and method for stimulating vulvar tissues and pelvic floor muscles for treating and improving dysfunction or disorders and probe unit used therefor
CN109862937A (zh) * 2016-08-25 2019-06-07 维兰德.K.沙马 用于电刺激肛门直肠结构以治疗泌尿功能障碍的系统和方法

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US20060184211A1 (en) 2004-01-22 2006-08-17 Gaunt Robert A Method of routing electrical current to bodily tissues via implanted passive conductors
US20170182319A1 (en) * 2007-08-02 2017-06-29 University Of Pittsburgh - Of The Commonwealth System Of Higher Education "Methods and Systems for Achieving a Physiological Response by Pudendal Nerve Stimulation and Blockade"
JP2017502786A (ja) 2014-01-17 2017-01-26 カーディアック ペースメイカーズ， インコーポレイテッド 神経連絡をブロックする枯渇ブロック

Also Published As

Publication number Publication date
CA3145807A1 (en) 2021-01-07
JP7609359B2 (ja) 2025-01-07
BR112021026805A2 (pt) 2022-02-15
KR20220035140A (ko) 2022-03-21
AU2020300506A1 (en) 2022-01-27
WO2021003151A1 (en) 2021-01-07
US20220395686A1 (en) 2022-12-15
AU2020300506B2 (en) 2025-09-04
EP3993865A4 (en) 2023-07-19
CN114286705A (zh) 2022-04-05
EP3993865A1 (en) 2022-05-11
JP2022539172A (ja) 2022-09-07

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