BR112021015600A2 - Métodos e composições para tratamento da apneia do sono - Google Patents
Métodos e composições para tratamento da apneia do sono Download PDFInfo
- Publication number
- BR112021015600A2 BR112021015600A2 BR112021015600-3A BR112021015600A BR112021015600A2 BR 112021015600 A2 BR112021015600 A2 BR 112021015600A2 BR 112021015600 A BR112021015600 A BR 112021015600A BR 112021015600 A2 BR112021015600 A2 BR 112021015600A2
- Authority
- BR
- Brazil
- Prior art keywords
- hypnotic
- myorelaxant
- atomoxetine
- nri
- sleep
- Prior art date
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- 238000000034 method Methods 0.000 title claims abstract description 53
- 201000002859 sleep apnea Diseases 0.000 title claims abstract description 9
- 238000011282 treatment Methods 0.000 title claims description 25
- 239000003158 myorelaxant agent Substances 0.000 claims abstract description 57
- 230000001670 myorelaxant effect Effects 0.000 claims abstract description 57
- 230000000147 hypnotic effect Effects 0.000 claims abstract description 52
- 239000005557 antagonist Substances 0.000 claims abstract description 32
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- 208000001797 obstructive sleep apnea Diseases 0.000 claims description 69
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| CN118557736A (zh) | 2019-02-08 | 2024-08-30 | 布里格姆妇女医院 | 用于治疗睡眠呼吸暂停的方法和组合物 |
| WO2022204228A1 (en) * | 2021-03-24 | 2022-09-29 | Apnimed, Inc. (Delaware) | Methods and compositions for treating sleep apnea |
| US20240277719A1 (en) * | 2021-06-17 | 2024-08-22 | Apnimed, Inc. (Delaware) | Norepinephrine reuptake inhibitors for treating sleep apnea |
| EP4522149A1 (en) * | 2022-05-13 | 2025-03-19 | Apnimed, Inc. (Delaware) | Methods and compositions for treating sleep apnea |
| KR20250057804A (ko) * | 2022-09-02 | 2025-04-29 | 애프니메드, 인코포레이티드 (델라웨어) | 수면 무호흡증을 치료하기 위한 방법 및 조성물 |
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| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| AU767877B2 (en) | 1999-05-20 | 2003-11-27 | Sepracor, Inc. | Methods for treatment of asthma using S-oxybutynin |
| PT1257277E (pt) | 2000-02-24 | 2005-09-30 | Pharmacia & Upjohn Co Llc | Novas combinacoes de farmacos |
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| US20030185882A1 (en) | 2001-11-06 | 2003-10-02 | Vergez Juan A. | Pharmaceutical compositions containing oxybutynin |
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| US20060039866A1 (en) | 2004-08-20 | 2006-02-23 | Cypress Bioscience, Inc. | Method for treating sleep-related breathing disorders |
| US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
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| FR2889811B1 (fr) | 2005-08-19 | 2009-10-09 | Sanofi Aventis Sa | Association d'un agent hypnotique a duree d'action longue et d'un agent hypnotique a duree d'action courte, composition pharmaceutique la contenant et son application en therapeutique. |
| PL2083811T3 (pl) | 2006-11-22 | 2017-05-31 | Clinical Research Associates, Llc | Sposoby leczenia zespołu downa, zespołu łamliwego chromosomu x oraz autyzmu |
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| EP2142183A2 (en) * | 2007-04-09 | 2010-01-13 | Sepracor Inc. | Methods and compositions comprising desvenlafaxine or duloxetine for treating sleep-related breathing disorders |
| EP2167096A4 (en) * | 2007-06-13 | 2010-07-14 | Cypress Bioscience Inc | IMPROVING TOLERANCE TO MIRTAZAPINE AND A SECOND ACTIVE INGREDIENT BY THE COMBINED USE OF THEM |
| AR069875A1 (es) | 2007-12-21 | 2010-02-24 | Eurand Inc | Composiciones de temazepam para tabletas de desintegracion oral y metodo de preparacion |
| US20100204058A1 (en) | 2009-01-28 | 2010-08-12 | Howard Yuan-Hao Chang | Profiling for Determination of Response to Treatment for Inflammatory Disease |
| JP2014503593A (ja) | 2011-01-28 | 2014-02-13 | ファンタスティック・メディカル・リサーチ・インスティテュート・エルエルシー | 閉塞性睡眠時無呼吸を処置するための方法 |
| US20170304286A1 (en) | 2014-10-24 | 2017-10-26 | Launx Biomedical Co., Ltd. | New indication of paroxetine pharmaceutical composition for treating cancer |
| MX373319B (es) * | 2015-04-27 | 2020-06-13 | Arena Pharm Inc | Derivados de hexahidro-[1-4]diazepino[6,7,1-hi]indol-8-carboxamida como agonistas del receptor 5-ht2c y el uso de los mismos en el tratamiento de enfermedades relacionadas con dicho receptor. |
| US10022355B2 (en) | 2015-06-12 | 2018-07-17 | Axovant Sciences Gmbh | Diaryl and arylheteroaryl urea derivatives as modulators of the 5-HT2A serotonin receptor useful for the prophylaxis and treatment of REM sleep behavior disorder |
| ES2925951T3 (es) * | 2015-07-22 | 2022-10-20 | John Hsu | Composición que comprende un agente terapéutico y un estimulante respiratorio y métodos para su uso |
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| KR102874891B1 (ko) | 2018-01-30 | 2025-10-21 | 애프니메드, 인코포레이티드 (델라웨어) | 수면 무호흡증을 치료하기 위한 방법 및 조성물 |
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