BR112020024740A2 - composto de fórmula (i) ou um sal farmaceuticamente aceitável do mesmo, uso deste, método de tratamento de uma doença ou condição mediada pelo receptor klk-5 em um humano e composição farmacêutica - Google Patents
composto de fórmula (i) ou um sal farmaceuticamente aceitável do mesmo, uso deste, método de tratamento de uma doença ou condição mediada pelo receptor klk-5 em um humano e composição farmacêutica Download PDFInfo
- Publication number
- BR112020024740A2 BR112020024740A2 BR112020024740-5A BR112020024740A BR112020024740A2 BR 112020024740 A2 BR112020024740 A2 BR 112020024740A2 BR 112020024740 A BR112020024740 A BR 112020024740A BR 112020024740 A2 BR112020024740 A2 BR 112020024740A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- pharmaceutically acceptable
- hydroxy
- ylmethoxy
- pyridin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1809378.1A GB201809378D0 (en) | 2018-06-07 | 2018-06-07 | Novel compounds |
| GB1809378.1 | 2018-06-07 | ||
| PCT/EP2019/064599 WO2019234075A1 (en) | 2018-06-07 | 2019-06-05 | Novel benzimidamides compounds comprising an oxaborinin ring |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112020024740A2 true BR112020024740A2 (pt) | 2021-03-23 |
Family
ID=62975712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112020024740-5A BR112020024740A2 (pt) | 2018-06-07 | 2019-06-05 | composto de fórmula (i) ou um sal farmaceuticamente aceitável do mesmo, uso deste, método de tratamento de uma doença ou condição mediada pelo receptor klk-5 em um humano e composição farmacêutica |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11352372B2 (https=) |
| EP (1) | EP3802550B1 (https=) |
| JP (1) | JP7317866B2 (https=) |
| KR (1) | KR102661802B1 (https=) |
| CN (2) | CN112236433B (https=) |
| BR (1) | BR112020024740A2 (https=) |
| ES (1) | ES2973710T3 (https=) |
| GB (1) | GB201809378D0 (https=) |
| WO (1) | WO2019234075A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200040103A1 (en) | 2018-03-14 | 2020-02-06 | Genentech, Inc. | Anti-klk5 antibodies and methods of use |
| GB201809378D0 (en) * | 2018-06-07 | 2018-07-25 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| PE20221906A1 (es) | 2019-09-18 | 2022-12-23 | Genentech Inc | Anticuerpos anti-klk7, anticuerpos anti-klk5, anticuerpos multiespecificos anti-klk5/klk7 y metodos de uso |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ578297A (en) * | 2005-02-16 | 2010-11-26 | Anacor Pharmaceuticals Inc | Boron-containing small molecules |
| ES2575131T3 (es) | 2007-12-03 | 2016-06-24 | Obe Therapy Biotechnology | Inhibidores boropéptidos de enteropeptidasa y sus usos en tratamientos de obesidad, sobrepeso y/o enfermedades asociadas con un metabolismo anormal de la grasa |
| CN102014927A (zh) * | 2008-03-06 | 2011-04-13 | 安纳考尔医药公司 | 作为抗炎药的含硼的小分子 |
| DK3097085T3 (da) | 2014-01-23 | 2020-10-26 | Sixera Pharma Ab | Benzoxazinonderivater til behandling af hudsygdomme |
| PT3097084T (pt) | 2014-01-23 | 2020-12-09 | Sixera Pharma Ab | Novos inibidores de calicreína 7 |
| GB201809378D0 (en) * | 2018-06-07 | 2018-07-25 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
-
2018
- 2018-06-07 GB GBGB1809378.1A patent/GB201809378D0/en not_active Ceased
-
2019
- 2019-06-05 ES ES19729249T patent/ES2973710T3/es active Active
- 2019-06-05 BR BR112020024740-5A patent/BR112020024740A2/pt active Search and Examination
- 2019-06-05 KR KR1020217000497A patent/KR102661802B1/ko active Active
- 2019-06-05 CN CN201980037789.9A patent/CN112236433B/zh active Active
- 2019-06-05 CN CN202310268678.7A patent/CN116217603A/zh active Pending
- 2019-06-05 WO PCT/EP2019/064599 patent/WO2019234075A1/en not_active Ceased
- 2019-06-05 EP EP19729249.3A patent/EP3802550B1/en active Active
- 2019-06-05 US US16/972,732 patent/US11352372B2/en active Active
- 2019-06-05 JP JP2020567854A patent/JP7317866B2/ja active Active
-
2022
- 2022-05-06 US US17/738,097 patent/US11767333B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019234075A1 (en) | 2019-12-12 |
| US20220267357A1 (en) | 2022-08-25 |
| JP7317866B2 (ja) | 2023-07-31 |
| US11767333B2 (en) | 2023-09-26 |
| EP3802550A1 (en) | 2021-04-14 |
| GB201809378D0 (en) | 2018-07-25 |
| CN112236433B (zh) | 2023-04-04 |
| US20210253604A1 (en) | 2021-08-19 |
| JP2021530440A (ja) | 2021-11-11 |
| CN116217603A (zh) | 2023-06-06 |
| US11352372B2 (en) | 2022-06-07 |
| KR20210018464A (ko) | 2021-02-17 |
| ES2973710T3 (es) | 2024-06-24 |
| EP3802550B1 (en) | 2023-12-27 |
| KR102661802B1 (ko) | 2024-04-26 |
| CN112236433A (zh) | 2021-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] |