BR112019020058A2 - formas de cristal inovadoras de um inibidor de pol1 - Google Patents

formas de cristal inovadoras de um inibidor de pol1 Download PDF

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Publication number
BR112019020058A2
BR112019020058A2 BR112019020058-4A BR112019020058A BR112019020058A2 BR 112019020058 A2 BR112019020058 A2 BR 112019020058A2 BR 112019020058 A BR112019020058 A BR 112019020058A BR 112019020058 A2 BR112019020058 A2 BR 112019020058A2
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BR
Brazil
Prior art keywords
crystalline form
crystalline
compound
document
analysis
Prior art date
Application number
BR112019020058-4A
Other languages
English (en)
Portuguese (pt)
Inventor
Mustapha Haddach
Original Assignee
Pimera, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pimera, Inc. filed Critical Pimera, Inc.
Publication of BR112019020058A2 publication Critical patent/BR112019020058A2/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BR112019020058-4A 2017-03-28 2018-03-28 formas de cristal inovadoras de um inibidor de pol1 BR112019020058A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762477746P 2017-03-28 2017-03-28
US62/477,746 2017-03-28
US201762491635P 2017-04-28 2017-04-28
US62/491,635 2017-04-28
PCT/US2018/024898 WO2018183540A1 (en) 2017-03-28 2018-03-28 Novel crystal forms of a pol1 inhibitor

Publications (1)

Publication Number Publication Date
BR112019020058A2 true BR112019020058A2 (pt) 2020-07-14

Family

ID=63676829

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019020058-4A BR112019020058A2 (pt) 2017-03-28 2018-03-28 formas de cristal inovadoras de um inibidor de pol1

Country Status (7)

Country Link
US (2) US11912706B2 (enExample)
EP (1) EP3601286A4 (enExample)
JP (3) JP2020512975A (enExample)
CN (2) CN110709400A (enExample)
BR (1) BR112019020058A2 (enExample)
CA (1) CA3057741A1 (enExample)
WO (1) WO2018183540A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9758518B2 (en) 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
CN110709400A (zh) 2017-03-28 2020-01-17 皮梅拉股份有限公司 Pol1抑制剂的新型晶体形式

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CN110709400A (zh) 2017-03-28 2020-01-17 皮梅拉股份有限公司 Pol1抑制剂的新型晶体形式

Also Published As

Publication number Publication date
CN115583948A (zh) 2023-01-10
JP2020512975A (ja) 2020-04-30
CN110709400A (zh) 2020-01-17
JP2023126708A (ja) 2023-09-08
CA3057741A1 (en) 2018-10-04
EP3601286A4 (en) 2020-09-23
US11912706B2 (en) 2024-02-27
US20230192694A1 (en) 2023-06-22
WO2018183540A1 (en) 2018-10-04
JP2025060702A (ja) 2025-04-10
US20250243200A1 (en) 2025-07-31
EP3601286A1 (en) 2020-02-05

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Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]