BR112019018576A2 - métodos de tratamento de doença de crohn e colite ulcerativa - Google Patents

métodos de tratamento de doença de crohn e colite ulcerativa Download PDF

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Publication number
BR112019018576A2
BR112019018576A2 BR112019018576-3A BR112019018576A BR112019018576A2 BR 112019018576 A2 BR112019018576 A2 BR 112019018576A2 BR 112019018576 A BR112019018576 A BR 112019018576A BR 112019018576 A2 BR112019018576 A2 BR 112019018576A2
Authority
BR
Brazil
Prior art keywords
patient
upadacitinib
weeks
pharmaceutically acceptable
acceptable salt
Prior art date
Application number
BR112019018576-3A
Other languages
English (en)
Portuguese (pt)
Inventor
B. THAKKAR Roopal
JUNGERWIRTH Steven
Paula Machado De Lacerda Ana
M. ROBINSON Anne
Jeffrey V. ENEJOSA Jose
L. PANGAN Aileen
Mohamed Mohamed-Eslam
Othman Ahmed
KLÜNDER Ben
D. Allian Ayman
B. Borchardt Thomas
Lars Nordstrom Fredrik
Y. Sheikh Ahmad
M. Mulhern Mathew
Jayanth Jayanthy
T. Mayer Peter
J. Marroum Patrick
Original Assignee
Abbvie Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=61750557&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112019018576(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc. filed Critical Abbvie Inc.
Publication of BR112019018576A2 publication Critical patent/BR112019018576A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BR112019018576-3A 2017-03-09 2018-03-09 métodos de tratamento de doença de crohn e colite ulcerativa BR112019018576A2 (pt)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201762469337P 2017-03-09 2017-03-09
US62/469,337 2017-03-09
US201762470565P 2017-03-13 2017-03-13
US62/470,565 2017-03-13
US201762483289P 2017-04-07 2017-04-07
US62/483,289 2017-04-07
US201762593629P 2017-12-01 2017-12-01
US62/593,629 2017-12-01
PCT/US2018/021800 WO2018165581A1 (en) 2017-03-09 2018-03-09 Methods of treating crohn's disease and ulcerative colitis

Publications (1)

Publication Number Publication Date
BR112019018576A2 true BR112019018576A2 (pt) 2020-04-14

Family

ID=61750557

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019018576-3A BR112019018576A2 (pt) 2017-03-09 2018-03-09 métodos de tratamento de doença de crohn e colite ulcerativa

Country Status (9)

Country Link
US (3) US20190046527A1 (https=)
EP (2) EP3592353A1 (https=)
JP (3) JP2020510016A (https=)
CN (2) CN120661512A (https=)
AU (2) AU2018230500B2 (https=)
BR (1) BR112019018576A2 (https=)
MX (2) MX2019010733A (https=)
TW (2) TWI851536B (https=)
WO (2) WO2018165581A1 (https=)

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US11524964B2 (en) 2015-10-16 2022-12-13 Abbvie Inc. Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
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CN114380837B (zh) * 2021-12-27 2023-06-30 上海邈金医药科技有限公司 一种具有Janus激酶抑制活性的化合物、包括该化合物的组合物及其应用
MX2024008557A (es) * 2022-01-13 2024-09-11 Abbvie Inc Método de administración de upadacitinib para evitar interacciones farmacologicas y efectos adversos.
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WO2024052820A1 (en) * 2022-09-09 2024-03-14 Intas Pharmaceuticals Ltd. Upadacitinib formulation
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Also Published As

Publication number Publication date
WO2018165581A1 (en) 2018-09-13
TW201840318A (zh) 2018-11-16
US20220233527A1 (en) 2022-07-28
CN110392572A (zh) 2019-10-29
WO2022178492A1 (en) 2022-08-25
US20210361647A1 (en) 2021-11-25
EP4487908A2 (en) 2025-01-08
JP2024009963A (ja) 2024-01-23
JP2026041823A (ja) 2026-03-10
AU2018230500A1 (en) 2019-09-19
US11607411B2 (en) 2023-03-21
TW202517269A (zh) 2025-05-01
AU2018230500B2 (en) 2024-03-07
EP3592353A1 (en) 2020-01-15
CN120661512A (zh) 2025-09-19
MX2022015499A (es) 2023-01-24
AU2024203642A1 (en) 2024-06-20
TWI851536B (zh) 2024-08-11
AU2024203642B2 (en) 2025-08-21
JP2020510016A (ja) 2020-04-02
CA3052873A1 (en) 2018-09-13
EP4487908A3 (en) 2025-01-15
MX2019010733A (es) 2019-11-01
US20190046527A1 (en) 2019-02-14

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