BR112019007424A2 - método de diagnóstico complementar para uso no tratamento da síndrome do intestino irritável com intervenções dietéticas ou transplante de microbiota fecal - Google Patents

método de diagnóstico complementar para uso no tratamento da síndrome do intestino irritável com intervenções dietéticas ou transplante de microbiota fecal

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Publication number
BR112019007424A2
BR112019007424A2 BR112019007424A BR112019007424A BR112019007424A2 BR 112019007424 A2 BR112019007424 A2 BR 112019007424A2 BR 112019007424 A BR112019007424 A BR 112019007424A BR 112019007424 A BR112019007424 A BR 112019007424A BR 112019007424 A2 BR112019007424 A2 BR 112019007424A2
Authority
BR
Brazil
Prior art keywords
treatment
ibs
bowel syndrome
irritable bowel
diagnostic method
Prior art date
Application number
BR112019007424A
Other languages
English (en)
Inventor
Røseth Arne
Casen Christina
Terje Hegge Finn
Valeur Jørgen
Cvancarova Småstuen Milada
Original Assignee
Genetic Analysis As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Analysis As filed Critical Genetic Analysis As
Publication of BR112019007424A2 publication Critical patent/BR112019007424A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56916—Enterobacteria, e.g. shigella, salmonella, klebsiella, serratia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/10—Enterobacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

a presente invenção fornece um método de diagnóstico que pode ser usado para determinar a probabilidade de um indivíduo com síndrome do intestino irritável (ibs) responder ao tratamento com uma dieta de intervenção de ibs ou transplante de microbiota fecal (fmt). em particular, o método pode ser usado para prever ou determinar a probabilidade de uma resposta positiva do indivíduo com ibs ao tratamento com uma dieta de intervenção de ibs ou fmt, especialmente para determinar a probabilidade de que a intervenção dietética ou tmf possa ter um efeito positivo (isto é, benéfico) no trato gi do indivíduo, especificamente a microbiota do trato gi, ou outros sintomas ou complicações da ibs (por exemplo, redução da sua gravidade). o método da presente invenção baseia-se na análise da abundância de certas bactérias em amostras do trato gi, por exemplo, por análise de ácido nucleico.
BR112019007424A 2016-10-14 2017-10-13 método de diagnóstico complementar para uso no tratamento da síndrome do intestino irritável com intervenções dietéticas ou transplante de microbiota fecal BR112019007424A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1617519.2A GB201617519D0 (en) 2016-10-14 2016-10-14 A companion diagnostic method for use in the treatment of irritable bowel syndrome with dietary interventions or faecal microbiota transplant
PCT/EP2017/076261 WO2018069538A1 (en) 2016-10-14 2017-10-13 A companion diagnostic method for use in the treatment of irritable bowel syndrome with dietary interventions or faecal microbiota transplant

Publications (1)

Publication Number Publication Date
BR112019007424A2 true BR112019007424A2 (pt) 2019-07-02

Family

ID=57680683

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019007424A BR112019007424A2 (pt) 2016-10-14 2017-10-13 método de diagnóstico complementar para uso no tratamento da síndrome do intestino irritável com intervenções dietéticas ou transplante de microbiota fecal

Country Status (10)

Country Link
US (3) US10794909B2 (pt)
EP (1) EP3526340A1 (pt)
JP (1) JP7100045B2 (pt)
CN (1) CN110114471A (pt)
AU (1) AU2017342088B2 (pt)
BR (1) BR112019007424A2 (pt)
CA (1) CA3039144A1 (pt)
GB (1) GB201617519D0 (pt)
MX (1) MX2019004207A (pt)
WO (1) WO2018069538A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111261238A (zh) * 2020-01-15 2020-06-09 生态环境部南京环境科学研究所 PPCPs类有机化学品中温厌氧消化去除率预测模型的构建方法
EP3913371A1 (en) 2020-05-18 2021-11-24 Neuroimmun GmbH Method and kit for diagnosting irritable bowel syndrome and for its relief through dietary interventions
CN114686557A (zh) * 2022-03-07 2022-07-01 中国农业大学 用于评估食物过敏的肠道菌群生物标志物及其用途和试剂盒

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9709728D0 (en) 1997-05-13 1997-07-02 Dynal As Single step method
GB0001450D0 (en) 2000-01-21 2000-03-08 Genpoint As Cell isolation method
WO2007050656A2 (en) 2005-10-24 2007-05-03 Nestec S.A. Dietary fiber formulation and method of administration
WO2011043654A1 (en) * 2009-10-05 2011-04-14 Aak Patent B.V. Methods for diagnosing irritable bowel syndrome
GB201021399D0 (en) * 2010-12-16 2011-01-26 Genetic Analysis As Oligonucleotide probe set and methods of microbiota profiling
ES2792106T3 (es) * 2012-05-18 2020-11-10 Genome Res Ltd Métodos y grupos
CA2947962C (en) 2014-05-04 2024-01-16 Salix Pharmaceuticals, Inc. Ibs microbiota and uses thereof
JP7182872B2 (ja) 2014-10-29 2022-12-05 グリコム・アクティーゼルスカブ 過敏性腸症候群の治療のための合成組成物および方法
GB201505364D0 (en) * 2015-03-27 2015-05-13 Genetic Analysis As Method for determining gastrointestinal tract dysbiosis
CN105543385A (zh) 2016-01-29 2016-05-04 山东大学齐鲁医院 肠易激综合征微生物标志物及其应用

Also Published As

Publication number Publication date
GB201617519D0 (en) 2016-11-30
US11243203B2 (en) 2022-02-08
MX2019004207A (es) 2019-09-26
US20200400666A1 (en) 2020-12-24
RU2762266C1 (ru) 2021-12-17
JP7100045B2 (ja) 2022-07-12
AU2017342088A1 (en) 2019-05-02
EP3526340A1 (en) 2019-08-21
JP2019531096A (ja) 2019-10-31
AU2017342088B2 (en) 2023-11-16
US20200049708A1 (en) 2020-02-13
US10794909B2 (en) 2020-10-06
WO2018069538A1 (en) 2018-04-19
CA3039144A1 (en) 2018-04-19
US20220120747A1 (en) 2022-04-21
CN110114471A (zh) 2019-08-09

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B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
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