BR112019006348A2 - ensaios de ponto de cuidado - Google Patents
ensaios de ponto de cuidadoInfo
- Publication number
- BR112019006348A2 BR112019006348A2 BR112019006348A BR112019006348A BR112019006348A2 BR 112019006348 A2 BR112019006348 A2 BR 112019006348A2 BR 112019006348 A BR112019006348 A BR 112019006348A BR 112019006348 A BR112019006348 A BR 112019006348A BR 112019006348 A2 BR112019006348 A2 BR 112019006348A2
- Authority
- BR
- Brazil
- Prior art keywords
- alt1
- subject
- binding agent
- antibodies
- mass
- Prior art date
Links
- 239000011230 binding agent Substances 0.000 abstract 4
- 241000283984 Rodentia Species 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- 208000019423 liver disease Diseases 0.000 abstract 2
- 230000003908 liver function Effects 0.000 abstract 2
- 241000283953 Lagomorpha Species 0.000 abstract 1
- 230000027455 binding Effects 0.000 abstract 1
- 230000006870 function Effects 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54388—Immunochromatographic test strips based on lateral flow
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/91188—Transferases (2.) transferring nitrogenous groups (2.6)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/08—Hepato-biliairy disorders other than hepatitis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/08—Hepato-biliairy disorders other than hepatitis
- G01N2800/085—Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Communicable Diseases (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
um imunoensaio adequado para ponto de cuidado para avaliar a doença ou função do fígado compreendendo contatar uma amostra de sangue de um sujeito com um agente de ligação específico que reconhece um epítopo de alt1, que não é reconhecido por anticorpos de roedores, quando os anticorpos de roedores estão na presença de plasma humano, para formar um complexo antígeno-agente de ligação e detectar o complexo usando um segundo agente de ligação ou adicional ligado a, ou compreendendo, um repórter detectável; e detectar doença do fígado ou função do fígado no sujeito contingente mediante a concentração de massa de alt1 na amostra. kits ou dispositivos compreendendo anticorpos lagomorfos ou agentes de ligação compreendendo o componente de ligação ao antígeno do mesmo adequado para medir a concentração de massa de alt1 em uma amostra de sangue de um sujeito para determinar a função do fígado.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610878590.7A CN107884572A (zh) | 2016-09-30 | 2016-09-30 | 护理点测定法 |
| PCT/IB2017/055943 WO2018060904A1 (en) | 2016-09-30 | 2017-09-28 | Point of care assays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112019006348A2 true BR112019006348A2 (pt) | 2019-06-18 |
Family
ID=61762564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112019006348A BR112019006348A2 (pt) | 2016-09-30 | 2017-09-28 | ensaios de ponto de cuidado |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20190285633A1 (pt) |
| EP (1) | EP3523655A4 (pt) |
| CN (3) | CN107884572A (pt) |
| AU (1) | AU2017334408A1 (pt) |
| BR (1) | BR112019006348A2 (pt) |
| CA (1) | CA3038616A1 (pt) |
| IL (1) | IL265695A (pt) |
| PH (1) | PH12019500687A1 (pt) |
| WO (1) | WO2018060904A1 (pt) |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6306A (en) | 1849-04-10 | Sliding cut-off valve | ||
| US6599A (en) | 1849-07-17 | Vegetable-cutter | ||
| US222A (en) | 1837-06-10 | Truss for the retention and radical cure qe hernia | ||
| US610A (en) | 1838-02-15 | Improvement in fire-arms | ||
| US592822A (en) | 1897-11-02 | parker | ||
| US6268A (en) | 1849-04-03 | James h | ||
| US4018653A (en) | 1971-10-29 | 1977-04-19 | U.S. Packaging Corporation | Instrument for the detection of Neisseria gonorrhoeae without culture |
| US4016043A (en) | 1975-09-04 | 1977-04-05 | Akzona Incorporated | Enzymatic immunological method for the determination of antigens and antibodies |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4318980A (en) | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
| US4424279A (en) | 1982-08-12 | 1984-01-03 | Quidel | Rapid plunger immunoassay method and apparatus |
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| ATE148889T1 (de) | 1991-09-18 | 1997-02-15 | Affymax Tech Nv | Verfahren zur synthese der verschiedenen sammlungen von oligomeren |
| EP0882224A4 (en) | 1996-02-22 | 1999-06-09 | Dexall Biochemical Labs Inc | LIQUID PHASE IMMUNOASSAY WITH NON-CAPTURED SUBSTRATE |
| WO2002092768A2 (en) * | 2001-05-14 | 2002-11-21 | University Of Maryland, Baltimore | Novel alanine transaminase enzyme and methods of use |
| WO2005113761A2 (en) * | 2004-04-19 | 2005-12-01 | University Of Maryland, Baltimore | Novel alanine transaminase enzymes and methods of use |
| KR100825116B1 (ko) * | 2005-11-17 | 2008-04-25 | 최의열 | 간질환 진단을 위한 알라닌 아미노전이효소 검출용 조성물 및 이를 이용한 진단 키트 |
| WO2008037026A1 (en) | 2006-09-28 | 2008-04-03 | The Macfarlane Burnet Institute For Medical Research And Public Health Limited | A method of diagnosis and kit therefor |
-
2016
- 2016-09-30 CN CN201610878590.7A patent/CN107884572A/zh active Pending
-
2017
- 2017-09-28 WO PCT/IB2017/055943 patent/WO2018060904A1/en active Application Filing
- 2017-09-28 CN CN202311299913.3A patent/CN117368473A/zh active Pending
- 2017-09-28 BR BR112019006348A patent/BR112019006348A2/pt unknown
- 2017-09-28 US US16/337,783 patent/US20190285633A1/en active Pending
- 2017-09-28 CA CA3038616A patent/CA3038616A1/en active Pending
- 2017-09-28 AU AU2017334408A patent/AU2017334408A1/en active Pending
- 2017-09-28 CN CN201780073575.8A patent/CN109997043B/zh active Active
- 2017-09-28 EP EP17855123.0A patent/EP3523655A4/en active Pending
-
2019
- 2019-03-28 IL IL265695A patent/IL265695A/en unknown
- 2019-03-29 PH PH12019500687A patent/PH12019500687A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA3038616A1 (en) | 2018-04-05 |
| CN107884572A (zh) | 2018-04-06 |
| EP3523655A1 (en) | 2019-08-14 |
| CN109997043B (zh) | 2023-11-03 |
| CN117368473A (zh) | 2024-01-09 |
| IL265695A (en) | 2019-05-30 |
| PH12019500687A1 (en) | 2019-06-17 |
| WO2018060904A1 (en) | 2018-04-05 |
| US20190285633A1 (en) | 2019-09-19 |
| CN109997043A (zh) | 2019-07-09 |
| EP3523655A4 (en) | 2020-06-17 |
| AU2017334408A1 (en) | 2019-04-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] |