BR112018015444A2 - inaladores de pó seco - Google Patents
inaladores de pó secoInfo
- Publication number
- BR112018015444A2 BR112018015444A2 BR112018015444A BR112018015444A BR112018015444A2 BR 112018015444 A2 BR112018015444 A2 BR 112018015444A2 BR 112018015444 A BR112018015444 A BR 112018015444A BR 112018015444 A BR112018015444 A BR 112018015444A BR 112018015444 A2 BR112018015444 A2 BR 112018015444A2
- Authority
- BR
- Brazil
- Prior art keywords
- dry powder
- local
- powder inhalers
- diseases
- inhalers
- Prior art date
Links
- 239000000843 powder Substances 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 210000004072 lung Anatomy 0.000 abstract 2
- 206010002198 Anaphylactic reaction Diseases 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 206010028813 Nausea Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 206010047700 Vomiting Diseases 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 230000036783 anaphylactic response Effects 0.000 abstract 1
- 208000003455 anaphylaxis Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 239000013583 drug formulation Substances 0.000 abstract 1
- 229940112141 dry powder inhaler Drugs 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000008693 nausea Effects 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 230000036407 pain Effects 0.000 abstract 1
- 208000002815 pulmonary hypertension Diseases 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 238000012385 systemic delivery Methods 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 230000008673 vomiting Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0025—Mouthpieces therefor with caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/10—General characteristics of the apparatus with powered movement mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
- A61M2205/121—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit interface between cassette and base
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
- A61M2205/128—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with incorporated valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/14—Static flow deviators in tubes disturbing laminar flow in tubes, e.g. archimedes screws
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662289095P | 2016-01-29 | 2016-01-29 | |
US62/289,095 | 2016-01-29 | ||
PCT/US2017/015486 WO2017132601A1 (en) | 2016-01-29 | 2017-01-27 | Dry powder inhaler |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112018015444A2 true BR112018015444A2 (pt) | 2018-12-18 |
BR112018015444B1 BR112018015444B1 (pt) | 2023-12-19 |
Family
ID=59386335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018015444-0A BR112018015444B1 (pt) | 2016-01-29 | 2017-01-27 | Inalador de pó seco |
Country Status (12)
Country | Link |
---|---|
US (4) | US20170216538A1 (pt) |
EP (2) | EP3407870B1 (pt) |
JP (3) | JP2019504684A (pt) |
CN (2) | CN108778249B (pt) |
AU (2) | AU2017211410B2 (pt) |
BR (1) | BR112018015444B1 (pt) |
CA (2) | CA3199504A1 (pt) |
HK (1) | HK1258955A1 (pt) |
IL (1) | IL260823B1 (pt) |
MX (2) | MX2018009159A (pt) |
SG (1) | SG11201806304PA (pt) |
WO (1) | WO2017132601A1 (pt) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101306384B1 (ko) | 2004-08-23 | 2013-09-09 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는디케토디옥산염 |
EP1928423B1 (en) | 2005-09-14 | 2015-12-09 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
CA2982550C (en) | 2008-06-13 | 2020-08-25 | Mannkind Corporation | A dry powder inhaler and system for drug delivery |
CN102065942B (zh) | 2008-06-20 | 2013-12-11 | 曼金德公司 | 用于对吸入工作进行实时描绘的交互式设备和方法 |
TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
JP6018640B2 (ja) | 2011-10-24 | 2016-11-02 | マンカインド コーポレイション | 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム |
CN105451716A (zh) | 2013-07-18 | 2016-03-30 | 曼金德公司 | 热稳定性干粉药物组合物和方法 |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
WO2015200049A1 (en) | 2014-06-26 | 2015-12-30 | Island Breeze Systems Ca, Llc | Mdi related products and methods of use |
USD824015S1 (en) * | 2016-01-29 | 2018-07-24 | Mannkind Corporation | Inhaler |
USD841798S1 (en) * | 2016-01-29 | 2019-02-26 | Mannkind Corporation | Inhaler |
USD824016S1 (en) * | 2016-01-29 | 2018-07-24 | Mannkind Corporation | Inhaler |
USD824510S1 (en) * | 2016-01-29 | 2018-07-31 | Mannkind Corporation | Inhaler |
CA3023257A1 (en) * | 2016-05-05 | 2017-11-09 | Liquidia Technologies, Inc. | Dry powder treprostinil for the treatment of pulmonary hypertension |
US20180271826A1 (en) * | 2017-03-22 | 2018-09-27 | Colorado Can Llc | Dry powders of cannabinoids and methods for preparing dry powders |
USD834178S1 (en) * | 2017-05-19 | 2018-11-20 | Mannkind Corporation | Inhaler |
EP3641864A1 (en) * | 2017-06-23 | 2020-04-29 | Københavns Universitet | Inhaler with acoustic flow monitoring |
USD851748S1 (en) * | 2017-11-08 | 2019-06-18 | Mannkind Corporation | Inhaler |
US20210069106A1 (en) * | 2018-01-26 | 2021-03-11 | Novartis Ag | High dose delivery of inhaled therapeutics |
EP3801552A4 (en) * | 2018-06-07 | 2022-02-23 | MannKind Corporation | COMPOSITION AND METHOD OF INHALATION |
CA3133804A1 (en) * | 2019-03-22 | 2020-10-01 | Mannkind Corporation | Inhalable dry powders |
USD898187S1 (en) * | 2019-05-21 | 2020-10-06 | Receptor Holdings, Inc. | Inhaler device |
EP4041208A4 (en) * | 2019-09-18 | 2023-07-19 | Board of Regents, The University of Texas System | CANNABINOID COMPOSITIONS FOR ADMINISTRATION BY INHALATION |
CA3171220A1 (en) * | 2020-03-19 | 2021-09-23 | Glenn MATTES | Dried particle inhalation for delivery of cannabis |
EP4167979A1 (en) * | 2020-06-19 | 2023-04-26 | Cannovex BV | Pulmonary formulation comprising cannabinoids |
CN115089825A (zh) * | 2022-07-06 | 2022-09-23 | 苏州易合医药有限公司 | 肺部给药装置 |
WO2024059819A2 (en) | 2022-09-15 | 2024-03-21 | Tff Pharmaceuticals, Inc. | Compositions of cannabinoids for delivery by inhalation |
Family Cites Families (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5352461A (en) * | 1992-03-11 | 1994-10-04 | Pharmaceutical Discovery Corporation | Self assembling diketopiperazine drug delivery system |
US20060165606A1 (en) * | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
EP1082108B1 (en) * | 1997-12-03 | 2002-12-18 | Britannia Pharmaceuticals Limited | Improvements in medicaments for asthma treatment |
US7464706B2 (en) | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
US7305986B1 (en) | 1999-07-23 | 2007-12-11 | Mannkind Corporation | Unit dose capsules for use in a dry powder inhaler |
US20010036481A1 (en) * | 1999-08-25 | 2001-11-01 | Advanced Inhalation Research, Inc. | Modulation of release from dry powder formulations |
CA2483914A1 (en) * | 2002-05-07 | 2003-11-20 | Nektar Therapeutics | Capsules for dry powder inhalers and methods of making and using same |
WO2004054647A1 (en) * | 2002-12-13 | 2004-07-01 | Otsuka Pharmaceutical Co., Ltd. | Inhalation device for transpulmonary administration |
US20040265238A1 (en) * | 2003-06-27 | 2004-12-30 | Imtiaz Chaudry | Inhalable formulations for treating pulmonary hypertension and methods of using same |
CA2551127A1 (en) * | 2003-12-15 | 2005-07-07 | Alexza Pharmaceuticals, Inc. | Treatment of breakthrough pain by drug aerosol inhalation |
US7452524B2 (en) * | 2004-01-27 | 2008-11-18 | Gilead Sciences, Inc. | Method for improvement of tolerance for therapeutically effective agents delivered by inhalation |
DE102004006450B4 (de) * | 2004-02-05 | 2012-09-27 | Ing. Erich Pfeiffer Gmbh | Dosiervorrichtung |
WO2006014930A2 (en) * | 2004-07-26 | 2006-02-09 | Cotherix, Inc. | Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation |
BRPI0514263B8 (pt) | 2004-08-20 | 2021-05-25 | Mannkind Corp | método para a síntese de bis-3,6-[4-aminobutil]-2,5-dicetopiperazina n-protegida |
KR101306384B1 (ko) * | 2004-08-23 | 2013-09-09 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는디케토디옥산염 |
US20090170775A1 (en) * | 2004-10-08 | 2009-07-02 | Transition Therapeutics, Inc. | Vasoactive intestinal polypeptide compositions |
WO2006111169A1 (en) * | 2005-04-21 | 2006-10-26 | Gastrotech Pharma A/S | Pharmaceutical preparations of a glp-1 molecule and an anti-emetic drug |
EP1928423B1 (en) * | 2005-09-14 | 2015-12-09 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
JP2009519972A (ja) * | 2005-12-15 | 2009-05-21 | アキュスフィア, インコーポレイテッド | 粒子ベースの経肺投与または経鼻投与用製薬の製造方法 |
JP5797376B2 (ja) * | 2006-05-15 | 2015-10-21 | ユナイテッド セラピューティクス コーポレーション | 定量吸入器を用いたトレプロスチニル投与 |
US20080078382A1 (en) * | 2006-09-20 | 2008-04-03 | Lemahieu Edward | Methods and Systems of Delivering Medication Via Inhalation |
WO2008049000A2 (en) * | 2006-10-18 | 2008-04-24 | United Therapeutics Corporation | Combination therapy for pulmonary arterial hypertension |
WO2009026434A1 (en) * | 2007-08-21 | 2009-02-26 | Alkermes, Inc. | Pulmonary pharmaceutical formulations |
WO2009055742A2 (en) * | 2007-10-24 | 2009-04-30 | Mannkind Corporation | Delivery of active agents |
WO2009152160A1 (en) * | 2008-06-10 | 2009-12-17 | Gilead Sciences, Inc. | Inhaled carbaprostacyclin and prostacyclin prodrugs for the treatment of pulmonary arterial hypertension |
CA2982550C (en) | 2008-06-13 | 2020-08-25 | Mannkind Corporation | A dry powder inhaler and system for drug delivery |
EP2330893A4 (en) * | 2008-09-25 | 2013-01-09 | Aradigm Corp | DEEP PULMONARY ADMINISTRATION OF TREPROSTINIL |
CA2755514C (en) | 2009-03-18 | 2018-03-13 | Mannkind Corporation | Inhaler adaptor for a laser diffraction apparatus and method for measuring particle size distribution |
MX2011013313A (es) * | 2009-06-12 | 2012-01-25 | Mannkind Corp | Microparticulas de dicetopiperazina con contenidos de isomero definidos. |
ES2943333T3 (es) | 2009-06-12 | 2023-06-12 | Mannkind Corp | Micropartículas de dicetopiperazina con superficies específicas definidas |
RU2553881C2 (ru) * | 2009-11-02 | 2015-06-20 | Мэннкайнд Корпорэйшн | Реактор и способ производства частиц в процессе осаждения |
EP2496295A1 (en) | 2009-11-03 | 2012-09-12 | MannKind Corporation | An apparatus and method for simulating inhalation efforts |
AU2011271097B2 (en) * | 2010-06-21 | 2014-11-27 | Mannkind Corporation | Dry powder drug delivery system and methods |
CA2812417C (en) * | 2010-09-29 | 2019-10-22 | Pulmatrix, Inc. | Cationic dry powders |
KR101915241B1 (ko) * | 2010-09-29 | 2018-11-06 | 풀매트릭스 오퍼레이팅 컴퍼니, 인크 | 흡입용의 1가 금속 양이온 건조 분말 |
EP2526926A1 (de) * | 2011-05-25 | 2012-11-28 | Justus-Liebig-Universität Gießen | Biokompatible Nanopolymerpartikel mit Wirkstoffen für die pulmonale Applikation |
CN109999013A (zh) * | 2012-02-29 | 2019-07-12 | 普马特里克斯营业公司 | 可吸入干粉剂 |
JP2015526523A (ja) * | 2012-08-29 | 2015-09-10 | マンカインド コーポレイション | 高血糖症の治療のための方法および組成物 |
WO2014100231A1 (en) * | 2012-12-18 | 2014-06-26 | Kotzker Consulting Llc | Use of cannabinoids and terpenes for treatment of organophosphate and carbamate toxicity |
KR102391750B1 (ko) * | 2013-03-15 | 2022-04-28 | 맨카인드 코포레이션 | 미세결정성 디케토피페라진 조성물 및 방법 |
ITMI20130572A1 (it) * | 2013-04-10 | 2014-10-11 | Eratech Srl | Composizione comprendente almeno due polveri secche ottenute per spray dry per aumentare la stabilita' della formulazione |
CN105451716A (zh) * | 2013-07-18 | 2016-03-30 | 曼金德公司 | 热稳定性干粉药物组合物和方法 |
CA2938244A1 (en) * | 2014-02-07 | 2015-08-13 | Auspex Pharamaceuticals, Inc. | Novel pharmaceutical formulations |
WO2015138423A1 (en) * | 2014-03-11 | 2015-09-17 | Insmed Incorporated | Prostacylin compositions and methods for using the same |
TWI685348B (zh) * | 2014-05-08 | 2020-02-21 | 美國禮來大藥廠 | 速效胰島素組合物 |
US10328216B2 (en) * | 2016-01-20 | 2019-06-25 | Flurry Powders, Llc | Encapsulation of lipophilic ingredients in dispensible spray dried powders suitable for inhalation |
US20210085897A1 (en) * | 2018-04-06 | 2021-03-25 | Lupin Inc. | Medicament dispenser |
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2017
- 2017-01-27 EP EP17745037.6A patent/EP3407870B1/en active Active
- 2017-01-27 WO PCT/US2017/015486 patent/WO2017132601A1/en active Application Filing
- 2017-01-27 MX MX2018009159A patent/MX2018009159A/es unknown
- 2017-01-27 CN CN201780019240.8A patent/CN108778249B/zh active Active
- 2017-01-27 US US15/418,388 patent/US20170216538A1/en not_active Abandoned
- 2017-01-27 CA CA3199504A patent/CA3199504A1/en active Pending
- 2017-01-27 JP JP2018539341A patent/JP2019504684A/ja active Pending
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- 2017-01-27 SG SG11201806304PA patent/SG11201806304PA/en unknown
- 2017-01-27 CN CN202210468404.8A patent/CN114904100A/zh active Pending
- 2017-01-27 EP EP22177953.1A patent/EP4079291A1/en active Pending
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2018
- 2018-07-26 MX MX2023001592A patent/MX2023001592A/es unknown
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2019
- 2019-01-28 HK HK19101435.0A patent/HK1258955A1/zh unknown
- 2019-10-14 US US16/601,440 patent/US20200046917A1/en active Pending
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2021
- 2021-01-26 US US17/158,997 patent/US20210146071A1/en active Pending
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- 2022-08-12 JP JP2022128971A patent/JP2022160697A/ja active Pending
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- 2022-11-09 US US17/983,915 patent/US20230098083A1/en active Pending
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Publication number | Publication date |
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EP3407870A1 (en) | 2018-12-05 |
IL260823B1 (en) | 2024-04-01 |
EP3407870B1 (en) | 2022-06-29 |
MX2018009159A (es) | 2019-06-13 |
JP2019504684A (ja) | 2019-02-21 |
AU2017211410B2 (en) | 2022-10-13 |
AU2022224822A1 (en) | 2022-09-29 |
AU2017211410A1 (en) | 2018-08-09 |
EP4079291A1 (en) | 2022-10-26 |
CN108778249A (zh) | 2018-11-09 |
IL260823A (pt) | 2024-04-01 |
HK1258955A1 (zh) | 2019-11-22 |
MX2023001592A (es) | 2023-03-15 |
US20210146071A1 (en) | 2021-05-20 |
CA3012679A1 (en) | 2017-08-03 |
CA3199504A1 (en) | 2017-08-03 |
CN108778249B (zh) | 2022-05-27 |
BR112018015444B1 (pt) | 2023-12-19 |
US20170216538A1 (en) | 2017-08-03 |
WO2017132601A1 (en) | 2017-08-03 |
US20230098083A1 (en) | 2023-03-30 |
SG11201806304PA (en) | 2018-08-30 |
EP3407870A4 (en) | 2019-07-31 |
US20200046917A1 (en) | 2020-02-13 |
JP2022160697A (ja) | 2022-10-19 |
JP2023154079A (ja) | 2023-10-18 |
CA3012679C (en) | 2023-12-12 |
CN114904100A (zh) | 2022-08-16 |
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