BR112018013369A2 - compostos depsipeptídicos anti-helmínticos - Google Patents
compostos depsipeptídicos anti-helmínticosInfo
- Publication number
- BR112018013369A2 BR112018013369A2 BR112018013369-8A BR112018013369A BR112018013369A2 BR 112018013369 A2 BR112018013369 A2 BR 112018013369A2 BR 112018013369 A BR112018013369 A BR 112018013369A BR 112018013369 A2 BR112018013369 A2 BR 112018013369A2
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- animals
- depsipeptide compounds
- compositions
- birds
- Prior art date
Links
- OHRURASPPZQGQM-GCCNXGTGSA-N romidepsin Chemical class O1C(=O)[C@H](C(C)C)NC(=O)C(=C/C)/NC(=O)[C@H]2CSSCC\C=C\[C@@H]1CC(=O)N[C@H](C(C)C)C(=O)N2 OHRURASPPZQGQM-GCCNXGTGSA-N 0.000 title abstract 2
- 230000000507 anthelmentic effect Effects 0.000 title 1
- 241001465754 Metazoa Species 0.000 abstract 3
- 244000045947 parasite Species 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 108010002156 Depsipeptides Proteins 0.000 abstract 1
- 206010061217 Infestation Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Agronomy & Crop Science (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562272040P | 2015-12-28 | 2015-12-28 | |
| US62/272,040 | 2015-12-28 | ||
| PCT/US2016/066497 WO2017116702A1 (en) | 2015-12-28 | 2016-12-14 | Anthelmintic depsipeptide compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112018013369A2 true BR112018013369A2 (pt) | 2019-02-19 |
Family
ID=57868331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112018013369-8A BR112018013369A2 (pt) | 2015-12-28 | 2016-12-14 | compostos depsipeptídicos anti-helmínticos |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US10344056B2 (https=) |
| EP (1) | EP3397638B1 (https=) |
| JP (1) | JP6943859B2 (https=) |
| KR (2) | KR102427124B1 (https=) |
| CN (1) | CN108699052B (https=) |
| AR (1) | AR107249A1 (https=) |
| AU (2) | AU2016380868B2 (https=) |
| BR (1) | BR112018013369A2 (https=) |
| CA (1) | CA3009867C (https=) |
| CL (1) | CL2018001744A1 (https=) |
| CO (1) | CO2018006527A2 (https=) |
| HK (1) | HK1255391A1 (https=) |
| HU (1) | HUE065907T2 (https=) |
| IL (1) | IL260262B2 (https=) |
| MX (1) | MX2018007948A (https=) |
| MY (1) | MY194716A (https=) |
| NZ (1) | NZ743913A (https=) |
| PH (1) | PH12018501367B1 (https=) |
| RU (2) | RU2715556C2 (https=) |
| SG (1) | SG11201805368YA (https=) |
| TW (1) | TWI787165B (https=) |
| UY (1) | UY37050A (https=) |
| WO (1) | WO2017116702A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107835818B (zh) * | 2015-05-20 | 2022-04-29 | 勃林格殷格翰动物保健美国公司 | 驱虫缩酚酸肽化合物 |
| BR112018013369A2 (pt) | 2015-12-28 | 2019-02-19 | Merial, Inc. | compostos depsipeptídicos anti-helmínticos |
| WO2018039508A1 (en) | 2016-08-25 | 2018-03-01 | Merial, Inc. | Method for reducing unwanted effects in parasiticidal treatments |
| EP3541789A1 (en) | 2016-11-16 | 2019-09-25 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
| PT3579696T (pt) | 2017-02-08 | 2023-07-19 | Boehringer Ingelheim Animal Health Usa Inc | Modelo in vivo para infeção por vermes parasitários e métodos para avaliação de compostos antiparasíticos, que incluem compostos ativos contra a dirofilariose canina |
| EP3480195A1 (en) | 2017-11-07 | 2019-05-08 | Bayer Animal Health GmbH | Method for the synthesis of cyclic depsipeptides |
| IL274283B2 (en) | 2017-11-07 | 2025-03-01 | Bayer Animal Health Gmbh | Method for the synthesis of cyclic depsipeptides |
| MX2020005573A (es) * | 2017-11-29 | 2020-09-10 | Zoetis Services Llc | Depsipeptidos endoparasitarios. |
| US11583545B2 (en) | 2018-02-08 | 2023-02-21 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof |
| US20220071183A1 (en) | 2019-01-10 | 2022-03-10 | Zoetis Services Llc | Anthelmintic laboratory animal model for heartworm |
| MX2021011302A (es) | 2019-03-19 | 2022-01-19 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos. |
| JP2023516754A (ja) * | 2020-03-06 | 2023-04-20 | ライフマックス ラボラトリーズ インコーポレイテッド | 環状デプシペプチドの局所医薬製剤 |
| KR20230028268A (ko) | 2020-05-29 | 2023-02-28 | 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 | 구충성 헤테로시클릭 화합물 |
| CN116897044A (zh) | 2020-12-21 | 2023-10-17 | 勃林格殷格翰动物保健有限公司 | 包含异噁唑啉化合物的杀寄生虫环 |
| US12258193B2 (en) | 2022-02-17 | 2025-03-25 | Boehringer Ingelheim Vetmedica Gmbh | Method and system for providing a fluid product mailer |
| AU2024339424A1 (en) * | 2023-09-15 | 2026-03-26 | Animol Discovery, Inc. | Antiparasitic cyclic depsipeptides |
| WO2025202940A2 (en) * | 2024-03-27 | 2025-10-02 | Animol Discovery, Inc. | Antiparasitic cyclic depsipeptides |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO176766C (no) | 1989-02-07 | 1995-05-24 | Meiji Seika Kaisha | Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet |
| NZ249588A (en) | 1992-03-17 | 1996-08-27 | Fujisawa Pharmaceutical Co | Anthelmintic agent |
| US5747448A (en) | 1993-02-19 | 1998-05-05 | Meiji Seika Kaisha, Ltd. | Derivatives of cyclodepsipeptide PF 1022 |
| DE4317457A1 (de) * | 1993-05-26 | 1994-12-01 | Bayer Ag | Octacyclodepsipeptide mit endoparasitizider Wirkung |
| DE4317432A1 (de) | 1993-05-26 | 1994-12-01 | Bayer Ag | Octacyclodepsipeptide mit endoparasitizider Wirkung |
| NZ271739A (en) | 1993-09-06 | 1996-09-25 | Fujisawa Pharmaceutical Co | Cyclodepsipeptide compounds and pharmaceutical compositions thereof |
| SE9303657D0 (sv) | 1993-11-05 | 1993-11-05 | Astra Ab | Short-acting dihydropyridines |
| DE4400464A1 (de) * | 1994-01-11 | 1995-07-13 | Bayer Ag | Endoparasitizide Mittel |
| DE4437198A1 (de) | 1994-10-18 | 1996-04-25 | Bayer Ag | Verfahren zur Sulfonylierung, Sulfenylierung und Phosphorylierung von cyclischen Depsipeptiden |
| DE19520275A1 (de) | 1995-06-02 | 1996-12-05 | Bayer Ag | Endoparasitizide Mittel |
| ATE299871T1 (de) | 1995-09-22 | 2005-08-15 | Meiji Seika Kaisha | Neue zyklische depsipeptid pf1022 derivate |
| WO1998015523A1 (en) | 1996-10-07 | 1998-04-16 | Fujisawa Pharmaceutical Co., Ltd. | Process for producing depsipeptide derivatives and novel intermediates therefor |
| DE19713626A1 (de) | 1997-04-02 | 1998-10-08 | Bayer Ag | Neue Thiodepsipeptide zur Bekämpfung von Endoparasiten und ein einfaches Verfahren zu ihrer Herstellung |
| JP2002502398A (ja) | 1997-06-04 | 2002-01-22 | バイエル・アクチエンゲゼルシヤフト | デソキシシクロデプシペプチド及び内部寄生性生物の防除のためのその使用 |
| DE19811559A1 (de) | 1998-03-17 | 1999-09-23 | Bayer Ag | Cyclooctadepsipeptide |
| DE19828043A1 (de) | 1998-06-24 | 1999-12-30 | Bayer Ag | Ektoparasitizide Mittel |
| DE19921887A1 (de) | 1999-05-12 | 2000-11-16 | Bayer Ag | Endoparasitizide Mittel |
| DE19962147A1 (de) | 1999-12-22 | 2001-06-28 | Bayer Ag | Schädlingsbekämpfungsmittel / PF 1022-221 |
| DE19962145A1 (de) | 1999-12-22 | 2001-06-28 | Bayer Ag | Schädlingsbekämpfungsmittel/Depsipeptide |
| DE10008128A1 (de) | 2000-02-22 | 2001-08-23 | Bayer Ag | Endoparasitizide Mittel |
| DE10031044A1 (de) | 2000-06-26 | 2002-01-03 | Bayer Ag | Endoparasitizide Mittel zur freiwilligen oralen Aufnahme durch Tiere |
| DE10104362A1 (de) | 2001-02-01 | 2002-08-08 | Bayer Ag | Kristallmodifikation eines cyclischen Depsipeptids mit besserer Wirksamkeit |
| UY26592A1 (es) | 2001-02-20 | 2001-09-28 | Bayer Ag | Agentes endoparasiticidas |
| US6893652B2 (en) * | 2001-08-27 | 2005-05-17 | Wyeth | Endoparasiticidal gel composition |
| US20040236191A1 (en) | 2003-05-19 | 2004-11-25 | Poliska Steven A. | System and method for identifying and labeling livestock products, and managing data associated with those products |
| DE10358525A1 (de) | 2003-12-13 | 2005-07-07 | Bayer Healthcare Ag | Endoparasitizide Mittel zur topischen Applikation |
| ES2351972T3 (es) | 2004-02-27 | 2011-02-14 | Ic Services | Procedimiento y set para la identificación de animales. |
| DE102004055316A1 (de) | 2004-11-16 | 2006-05-18 | Bayer Healthcare Ag | Verhinderung vertikaler Endoparasiten-Infektionen |
| US20060202835A1 (en) | 2005-02-25 | 2006-09-14 | Osborne Industries, Inc. | Dual frequency identification device |
| DE102008022520A1 (de) | 2008-05-07 | 2009-11-12 | Bayer Animal Health Gmbh | Feste Arzneimittelformulierung mit verzögerter Freisetzung |
| DE102008030764A1 (de) | 2008-06-28 | 2009-12-31 | Bayer Animal Health Gmbh | Kombination von Amidin-Derivaten mit cyclischen Depsipeptiden |
| DE102008031283A1 (de) | 2008-07-02 | 2010-01-07 | Bayer Schering Pharma Aktiengesellschaft | Neue Bekämpfungsmöglichkeit von durch Trichomonadida hervorgerufenen Krankheiten |
| DE102008031284A1 (de) | 2008-07-02 | 2010-01-07 | Bayer Schering Pharma Aktiengesellschaft | Neue Bekämpfungsmöglichkeit der Giardiose |
| KR20110095350A (ko) | 2008-12-16 | 2011-08-24 | 바이엘 애니멀 헬스 게엠베하 | 로셀리니아 유형 및 자일라리에이시의 다른 종의 진균 균주를 사용하는, 락트산 및 페닐락트산을 포함하며 24개의 고리 원자를 갖는, 광학 활성의 시클릭 뎁시펩티드의 제조 방법 |
| KR101002530B1 (ko) | 2009-02-18 | 2010-12-17 | 삼성에스디아이 주식회사 | 알에프아이디 통신 장치 |
| EP2509967B1 (en) | 2009-12-11 | 2016-02-17 | Bayer Intellectual Property GmbH | Novel 24-membered cyclooctadepsipeptides from fungal strains and their use as anthelmintics or endoparasiticides |
| WO2012028556A1 (en) | 2010-08-31 | 2012-03-08 | Bayer Animal Health Gmbh | Macrocyclic lactones and their use and their combinations with other active substances |
| US20120124387A1 (en) | 2010-11-11 | 2012-05-17 | Skocic Ruth E | Animal Data Management |
| US9848290B2 (en) | 2011-03-10 | 2017-12-19 | Aruba Networks, Inc. | Location based computerized system and method thereof |
| CN104023710A (zh) | 2011-12-21 | 2014-09-03 | 拜耳知识产权有限责任公司 | 包含无定形艾默德斯的制剂 |
| KR20150037766A (ko) | 2012-06-13 | 2015-04-08 | 메이지 세이카 파루마 가부시키가이샤 | 신규한 환상 뎁시펩티드 유도체 및 이를 포함하는 해충 방제제 |
| US20140306005A1 (en) | 2013-04-14 | 2014-10-16 | Forever Yours, Inc. | Method for Data Transport and Recovery of Dependent Creatures |
| CN107835818B (zh) | 2015-05-20 | 2022-04-29 | 勃林格殷格翰动物保健美国公司 | 驱虫缩酚酸肽化合物 |
| BR112018013369A2 (pt) | 2015-12-28 | 2019-02-19 | Merial, Inc. | compostos depsipeptídicos anti-helmínticos |
| EP3541789A1 (en) | 2016-11-16 | 2019-09-25 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
-
2016
- 2016-12-14 BR BR112018013369-8A patent/BR112018013369A2/pt not_active Application Discontinuation
- 2016-12-14 MX MX2018007948A patent/MX2018007948A/es unknown
- 2016-12-14 JP JP2018534122A patent/JP6943859B2/ja not_active Expired - Fee Related
- 2016-12-14 EP EP16829348.8A patent/EP3397638B1/en active Active
- 2016-12-14 WO PCT/US2016/066497 patent/WO2017116702A1/en not_active Ceased
- 2016-12-14 CN CN201680082548.2A patent/CN108699052B/zh not_active Expired - Fee Related
- 2016-12-14 KR KR1020187021726A patent/KR102427124B1/ko active Active
- 2016-12-14 HK HK18114530.8A patent/HK1255391A1/zh unknown
- 2016-12-14 US US15/378,219 patent/US10344056B2/en active Active
- 2016-12-14 AU AU2016380868A patent/AU2016380868B2/en not_active Ceased
- 2016-12-14 SG SG11201805368YA patent/SG11201805368YA/en unknown
- 2016-12-14 CA CA3009867A patent/CA3009867C/en active Active
- 2016-12-14 MY MYPI2018001112A patent/MY194716A/en unknown
- 2016-12-14 RU RU2018127195A patent/RU2715556C2/ru active
- 2016-12-14 HU HUE16829348A patent/HUE065907T2/hu unknown
- 2016-12-14 NZ NZ743913A patent/NZ743913A/en not_active IP Right Cessation
- 2016-12-14 KR KR1020217043332A patent/KR20220003663A/ko not_active Abandoned
- 2016-12-14 PH PH1/2018/501367A patent/PH12018501367B1/en unknown
- 2016-12-14 RU RU2020107484A patent/RU2020107484A/ru unknown
- 2016-12-26 UY UY0001037050A patent/UY37050A/es not_active Application Discontinuation
- 2016-12-28 AR ARP160104061A patent/AR107249A1/es not_active Application Discontinuation
- 2016-12-28 TW TW105143547A patent/TWI787165B/zh not_active IP Right Cessation
-
2018
- 2018-06-25 IL IL260262A patent/IL260262B2/en unknown
- 2018-06-25 CO CONC2018/0006527A patent/CO2018006527A2/es unknown
- 2018-06-25 CL CL2018001744A patent/CL2018001744A1/es unknown
-
2019
- 2019-04-23 US US16/392,412 patent/US11230571B2/en active Active
-
2020
- 2020-02-06 AU AU2020200854A patent/AU2020200854B2/en not_active Ceased
-
2021
- 2021-12-08 US US17/643,251 patent/US12018048B2/en active Active
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