BR112018011589A2 - método para preparar um composto, e, composto. - Google Patents
método para preparar um composto, e, composto.Info
- Publication number
- BR112018011589A2 BR112018011589A2 BR112018011589A BR112018011589A BR112018011589A2 BR 112018011589 A2 BR112018011589 A2 BR 112018011589A2 BR 112018011589 A BR112018011589 A BR 112018011589A BR 112018011589 A BR112018011589 A BR 112018011589A BR 112018011589 A2 BR112018011589 A2 BR 112018011589A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- preparing
- compounds
- benzodioxol
- intermediates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
a presente invenção se refere a métodos inovadores para a preparação de compostos heterocíclicos de 1,3-benzodioxol e intermediários para os mesmos. os compostos são úteis como inibidores de pde4.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15201053.4 | 2015-12-18 | ||
| EP15201053 | 2015-12-18 | ||
| PCT/EP2016/081368 WO2017103058A1 (en) | 2015-12-18 | 2016-12-16 | Methods for the preparation of 1,3-benzodioxole heterocyclic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112018011589A2 true BR112018011589A2 (pt) | 2018-11-27 |
| BR112018011589B1 BR112018011589B1 (pt) | 2023-09-12 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| PT3390407T (pt) | 2023-11-03 |
| KR20180095888A (ko) | 2018-08-28 |
| EP3390407A1 (en) | 2018-10-24 |
| IL259617A (en) | 2018-07-31 |
| AU2016369371B2 (en) | 2020-12-24 |
| TW201725208A (zh) | 2017-07-16 |
| CN108368126B (zh) | 2021-10-08 |
| RU2018126363A (ru) | 2020-01-22 |
| US20200262842A1 (en) | 2020-08-20 |
| US20230073362A1 (en) | 2023-03-09 |
| HK1258964A1 (zh) | 2019-11-22 |
| MX2018007219A (es) | 2018-08-01 |
| TWI732808B (zh) | 2021-07-11 |
| RU2761337C2 (ru) | 2021-12-07 |
| CN108368126A (zh) | 2018-08-03 |
| IL259617B (en) | 2021-05-31 |
| CA3007432A1 (en) | 2017-06-22 |
| JP2018537510A (ja) | 2018-12-20 |
| AU2016369371A1 (en) | 2018-06-21 |
| ES2961237T3 (es) | 2024-03-11 |
| JP6934872B2 (ja) | 2021-09-15 |
| WO2017103058A1 (en) | 2017-06-22 |
| DK3390407T3 (da) | 2023-11-06 |
| AU2016369371C1 (en) | 2021-05-13 |
| CN114085234A (zh) | 2022-02-25 |
| RU2018126363A3 (pt) | 2020-03-26 |
| PL3390407T3 (pl) | 2024-01-29 |
| US11370799B2 (en) | 2022-06-28 |
| EP3390407B1 (en) | 2023-10-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: A CLASSIFICACAO ANTERIOR ERA: C07D 495/10 Ipc: C07D 495/10 (2006.01), A61K 31/36 (2006.01), A61K |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: UNION THERAPEUTICS A/S (DK) |
|
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/12/2016, OBSERVADAS AS CONDICOES LEGAIS |