PL3390407T3 - Sposoby otrzymywania heterocyklicznych związków 1,3-benzodioksolu - Google Patents

Sposoby otrzymywania heterocyklicznych związków 1,3-benzodioksolu

Info

Publication number
PL3390407T3
PL3390407T3 PL16816653.6T PL16816653T PL3390407T3 PL 3390407 T3 PL3390407 T3 PL 3390407T3 PL 16816653 T PL16816653 T PL 16816653T PL 3390407 T3 PL3390407 T3 PL 3390407T3
Authority
PL
Poland
Prior art keywords
preparation
methods
heterocyclic compounds
benzodioxole
benzodioxole heterocyclic
Prior art date
Application number
PL16816653.6T
Other languages
English (en)
Inventor
Allan Carsten Dahl
Gitte Holm JENSEN
Tine Marianne DUUS
Original Assignee
UNION therapeutics A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UNION therapeutics A/S filed Critical UNION therapeutics A/S
Publication of PL3390407T3 publication Critical patent/PL3390407T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL16816653.6T 2015-12-18 2016-12-16 Sposoby otrzymywania heterocyklicznych związków 1,3-benzodioksolu PL3390407T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15201053 2015-12-18
PCT/EP2016/081368 WO2017103058A1 (en) 2015-12-18 2016-12-16 Methods for the preparation of 1,3-benzodioxole heterocyclic compounds

Publications (1)

Publication Number Publication Date
PL3390407T3 true PL3390407T3 (pl) 2024-01-29

Family

ID=54850367

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16816653.6T PL3390407T3 (pl) 2015-12-18 2016-12-16 Sposoby otrzymywania heterocyklicznych związków 1,3-benzodioksolu

Country Status (17)

Country Link
US (3) US11370799B2 (pl)
EP (1) EP3390407B1 (pl)
JP (1) JP6934872B2 (pl)
KR (1) KR20180095888A (pl)
CN (2) CN114085234B (pl)
AU (1) AU2016369371C1 (pl)
CA (1) CA3007432A1 (pl)
DK (1) DK3390407T3 (pl)
ES (1) ES2961237T3 (pl)
IL (1) IL259617B (pl)
MX (1) MX385592B (pl)
NZ (1) NZ742952A (pl)
PL (1) PL3390407T3 (pl)
PT (1) PT3390407T (pl)
RU (1) RU2761337C2 (pl)
TW (1) TWI732808B (pl)
WO (1) WO2017103058A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3157930T3 (en) * 2014-06-23 2019-01-21 Leo Pharma As PROCEDURES FOR THE PREPARATION OF HETEROCYCLIC 1,3-BENZODIOXOL COMPOUNDS
CN114085234B (zh) 2015-12-18 2024-12-17 联合疗法公司 用于制备1,3-苯并间二氧杂环戊烯杂环化合物的方法
DK3642210T3 (da) 2017-06-20 2024-12-09 Union Therapeutics As Fremgangsmåder til fremstilling af heterocykliske 1,3-benzodioxolforbindelser
JP7203846B2 (ja) 2017-12-15 2023-01-13 ユニオン・セラピューティクス・アクティエセルスカブ 置換アゼチジンジヒドロチエノピリジンおよびホスホジエステラーゼ阻害剤としてのそれらの使用
RS64672B1 (sr) 2019-01-15 2023-11-30 Union Therapeutics As Formulacije tableta sa modifikovanim oslobađanjem koje sadrže inhibitore fosfodiesteraze
EP4313043A1 (en) 2021-03-22 2024-02-07 UNION therapeutics A/S Treatment of hidradenitis suppurativa with orismilast
GB202205715D0 (en) 2022-04-19 2022-06-01 Union Therapeutics As Treatment of neutrophilic dermatoses
GB202306662D0 (en) 2023-05-05 2023-06-21 Union Therapeutics As Dosage regimen
GB202306663D0 (en) 2023-05-05 2023-06-21 Union Therapeutics As Combination therapy

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514996B2 (en) 1995-05-19 2003-02-04 Kyowa Hakko Kogyo Co., Ltd. Derivatives of benzofuran or benzodioxole
DE10205274A1 (de) 2002-02-08 2003-08-21 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen enthaltend neben Anticholinergika heterocyclische Verbindungen
AU2003252467A1 (en) 2002-07-03 2004-01-23 Kyowa Hakko Kogyo Co., Ltd. Process for preparation of 1,3-benzodioxole-2-spiro- cycloalkane derivatives
JP2006008522A (ja) * 2004-06-22 2006-01-12 Sumitomo Chemical Co Ltd 2,3−ジヒドロキシ−4−アルコキシ−アシルベンゼン類の製造方法
EP2044023B1 (en) 2006-07-14 2011-01-19 CHIESI FARMACEUTICI S.p.A. Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors
BRPI0721113A2 (pt) 2006-12-22 2014-10-07 Leo Pharma As Composto, composição farmacêutica, uso de um composto, e, método para prevenir, tratar ou melhorar doenças ou condições dérmicas ou distúrbios
ES2478670T3 (es) 2007-02-28 2014-07-22 Leo Pharma A/S Nuevos inhibidores de la fosfodiesterasa
CN101631792B (zh) * 2007-02-28 2013-05-01 利奥制药有限公司 新的磷酸二酯酶抑制剂
US8980905B2 (en) 2010-06-24 2015-03-17 Leo Pharma A/S Benzodioxole or benzodioxepine heterocyclic compounds as phosphodiesterase inhibitors
JP2012229192A (ja) * 2011-04-13 2012-11-22 Jsr Corp (ポリ)イソシアヌレート化合物の製造方法
WO2014096018A1 (en) * 2012-12-19 2014-06-26 Leo Pharma A/S Methods for the preparation of substituted acetophenones
DK3157930T3 (en) * 2014-06-23 2019-01-21 Leo Pharma As PROCEDURES FOR THE PREPARATION OF HETEROCYCLIC 1,3-BENZODIOXOL COMPOUNDS
CN114085234B (zh) 2015-12-18 2024-12-17 联合疗法公司 用于制备1,3-苯并间二氧杂环戊烯杂环化合物的方法
DK3642210T3 (da) 2017-06-20 2024-12-09 Union Therapeutics As Fremgangsmåder til fremstilling af heterocykliske 1,3-benzodioxolforbindelser

Also Published As

Publication number Publication date
EP3390407B1 (en) 2023-10-11
MX385592B (es) 2025-03-18
IL259617B (en) 2021-05-31
DK3390407T3 (da) 2023-11-06
US20200262842A1 (en) 2020-08-20
RU2761337C2 (ru) 2021-12-07
HK1258964A1 (zh) 2019-11-22
CA3007432A1 (en) 2017-06-22
CN108368126B (zh) 2021-10-08
WO2017103058A1 (en) 2017-06-22
CN108368126A (zh) 2018-08-03
CN114085234B (zh) 2024-12-17
US20260035383A1 (en) 2026-02-05
NZ742952A (en) 2025-02-28
PT3390407T (pt) 2023-11-03
KR20180095888A (ko) 2018-08-28
ES2961237T3 (es) 2024-03-11
IL259617A (en) 2018-07-31
CN114085234A (zh) 2022-02-25
TWI732808B (zh) 2021-07-11
US11370799B2 (en) 2022-06-28
RU2018126363A3 (pl) 2020-03-26
JP2018537510A (ja) 2018-12-20
EP3390407A1 (en) 2018-10-24
AU2016369371C1 (en) 2021-05-13
BR112018011589A2 (en) 2018-11-27
JP6934872B2 (ja) 2021-09-15
TW201725208A (zh) 2017-07-16
MX2018007219A (es) 2018-08-01
AU2016369371B2 (en) 2020-12-24
US20230073362A1 (en) 2023-03-09
RU2018126363A (ru) 2020-01-22
AU2016369371A1 (en) 2018-06-21

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