BR112018010384A2 - levedura geneticamente modificada e processo para fabricar um produto de fermentação - Google Patents

levedura geneticamente modificada e processo para fabricar um produto de fermentação

Info

Publication number
BR112018010384A2
BR112018010384A2 BR112018010384A BR112018010384A BR112018010384A2 BR 112018010384 A2 BR112018010384 A2 BR 112018010384A2 BR 112018010384 A BR112018010384 A BR 112018010384A BR 112018010384 A BR112018010384 A BR 112018010384A BR 112018010384 A2 BR112018010384 A2 BR 112018010384A2
Authority
BR
Brazil
Prior art keywords
fermentation
yeast
making
fermentation product
genetically modified
Prior art date
Application number
BR112018010384A
Other languages
English (en)
Inventor
M Fosmer Arlene
Rush Brian
M Poynter Gregory
Alan Jauert Peter
Original Assignee
Cargill Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cargill Inc filed Critical Cargill Inc
Publication of BR112018010384A2 publication Critical patent/BR112018010384A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/14—Multiple stages of fermentation; Multiple types of microorganisms or re-use of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01026—Beta-fructofuranosidase (3.2.1.26), i.e. invertase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01005—Xylose isomerase (5.3.1.5)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Abstract

a presente invenção refere-se a uma levedura geneticamente manipulada capaz de fabricar um produto de fermentação usando sacarose como substrato de fermentação e processos de fermentação usando essa levedura. a levedura possui um gene de invertase exógeno e possui uma deleção ou ruptura do gene da atividade de pdc. por conseguinte, a levedura é útil para a fabricação de produtos de fermentação diferentes do etanol a partir de substratos de fermentação contendo sacarose.
BR112018010384A 2015-11-24 2016-11-22 levedura geneticamente modificada e processo para fabricar um produto de fermentação BR112018010384A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562259531P 2015-11-24 2015-11-24
PCT/US2016/063401 WO2017091610A1 (en) 2015-11-24 2016-11-22 Genetically modified yeasts and fermentation processes using genetically modified yeasts

Publications (1)

Publication Number Publication Date
BR112018010384A2 true BR112018010384A2 (pt) 2018-12-04

Family

ID=57544541

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112018010387A BR112018010387A8 (pt) 2015-11-24 2016-11-22 levedura geneticamente modificada e processo para fabricar etanol
BR112018010384A BR112018010384A2 (pt) 2015-11-24 2016-11-22 levedura geneticamente modificada e processo para fabricar um produto de fermentação

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BR112018010387A BR112018010387A8 (pt) 2015-11-24 2016-11-22 levedura geneticamente modificada e processo para fabricar etanol

Country Status (6)

Country Link
US (3) US10731184B2 (pt)
EP (3) EP3380624A1 (pt)
AU (2) AU2016361425B2 (pt)
BR (2) BR112018010387A8 (pt)
CA (2) CA3004177A1 (pt)
WO (2) WO2017091614A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3380624A1 (en) 2015-11-24 2018-10-03 Cargill, Incorporated Genetically modified yeasts and fermentation processes using genetically modified yeasts
WO2022250697A1 (en) * 2021-05-28 2022-12-01 Cargill, Incorporated Fermentation method for producing malonic acid
WO2023023448A1 (en) 2021-08-18 2023-02-23 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of lactate
CN117813388A (zh) 2021-08-18 2024-04-02 嘉吉公司 用于生产乳酸盐的遗传修饰的酵母和发酵工艺
WO2023168244A1 (en) 2022-03-03 2023-09-07 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of 3-hydroxypropionate
WO2023168233A1 (en) 2022-03-03 2023-09-07 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of 3-hydroxypropionate
CN116144516B (zh) * 2023-03-10 2023-08-08 江南大学 一株产丁二酸的酿酒酵母及其应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2198410T3 (es) 1993-07-23 2004-02-01 Dsm Ip Assets B.V. Cepas recombinantes de hongos filamentosos libres de gen marcador de seleccion: un metodo para obtener dichas cepas y su utilizacion.
IT1294728B1 (it) 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US20070031950A1 (en) 1998-09-11 2007-02-08 Winkler Aaron A Production of D-lactic acid with yeast
PL352434A1 (en) 1999-05-21 2003-08-25 Cargill Dow Llc Methods and materials for the synthesis of organic products
WO2002042471A2 (en) 2000-11-22 2002-05-30 Cargill Dow Polymers Llc Methods and materials for the synthesis of organic products
PL1626979T3 (pl) 2003-05-02 2012-09-28 Cargill Inc Genetycznie modyfikowane gatunki drożdży i sposoby fermentacji z użyciem genetycznie modyfikowanych drożdży
BRPI0610951A2 (pt) 2005-06-02 2010-08-03 Cargill Inc levedura geneticamente modificada da espécie issatchenkia orientalis e espécies estreitamente relacionadas e processos de fermentação utilizando as mesmas
US9334488B2 (en) * 2008-12-24 2016-05-10 Dsm Ip Assets B.V. Xylose isomerase genes and their use in fermentation of pentose sugars
CN102498209A (zh) 2009-08-21 2012-06-13 旭硝子株式会社 转化体及其制造方法以及乳酸的制造方法
PL2655612T3 (pl) 2010-12-23 2017-12-29 Shell Internationale Research Maatschappij B.V. Czynniki uszkadzające geny produkujące pochodne tłuszczowego acylo-coa
KR20140000711A (ko) * 2010-12-30 2014-01-03 이 아이 듀폰 디 네모아 앤드 캄파니 수크로스 이용에 있어서의 야로위아 리포라이티카에서의 사카로마이세스 세레비지애 suc2 유전자의 용도
CA2832587A1 (en) 2011-04-11 2012-10-18 Cargill, Incorporated Compositions and methods for increased ethanol production from biomass
US9885065B2 (en) * 2012-01-25 2018-02-06 Bioamber Inc. Methods for succinate production
US9850507B2 (en) * 2012-07-25 2017-12-26 Cargill, Incorporated Yeast cells having reductive TCA pathway from pyruvate to succinate and overexpressing an exogenous NAD(P)+ transhydrogenase enzyme
US9187743B2 (en) * 2013-03-11 2015-11-17 E I Du Pont De Nemours And Company Bacterial xylose isomerases active in yeast cells
EP3380624A1 (en) 2015-11-24 2018-10-03 Cargill, Incorporated Genetically modified yeasts and fermentation processes using genetically modified yeasts

Also Published As

Publication number Publication date
US20200362371A1 (en) 2020-11-19
EP3380626A1 (en) 2018-10-03
BR112018010387A8 (pt) 2019-02-26
US10731184B2 (en) 2020-08-04
WO2017091614A1 (en) 2017-06-01
CA3004176A1 (en) 2017-06-01
AU2016361425B2 (en) 2021-04-01
US20180346937A1 (en) 2018-12-06
WO2017091610A1 (en) 2017-06-01
EP3380626B1 (en) 2020-10-21
AU2016361425A1 (en) 2018-05-17
AU2016361421B2 (en) 2021-04-01
EP3380624A1 (en) 2018-10-03
CA3004177A1 (en) 2017-06-01
BR112018010387A2 (pt) 2018-11-21
US10738332B2 (en) 2020-08-11
US20180346939A1 (en) 2018-12-06
EP3825410A1 (en) 2021-05-26
AU2016361421A1 (en) 2018-05-17

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]