BR112018001782A2 - oligonucleotídeo para uso no tratamento e/ou prevenção de uma doença que compreende o alongamento alternativo dos telômeros, oligonucleotídeo para uso no tratamento e/ou prevenção de uma condição não cancerosa associada à disfunção do telômero e composição farmacêutica - Google Patents

oligonucleotídeo para uso no tratamento e/ou prevenção de uma doença que compreende o alongamento alternativo dos telômeros, oligonucleotídeo para uso no tratamento e/ou prevenção de uma condição não cancerosa associada à disfunção do telômero e composição farmacêutica

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Publication number
BR112018001782A2
BR112018001782A2 BR112018001782A BR112018001782A BR112018001782A2 BR 112018001782 A2 BR112018001782 A2 BR 112018001782A2 BR 112018001782 A BR112018001782 A BR 112018001782A BR 112018001782 A BR112018001782 A BR 112018001782A BR 112018001782 A2 BR112018001782 A2 BR 112018001782A2
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Brazil
Prior art keywords
oligonucleotide
prevention
treatment
telomere
seq
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BR112018001782A
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English (en)
Inventor
Jones-Weinert Corey
D'adda Di Fagagna Fabrizio
Rossiello Francesca
Aguado Julio
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Ifom Fondazione St Firc Di Oncologia Molecolare
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Publication of BR112018001782A2 publication Critical patent/BR112018001782A2/pt

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Abstract

a presente invenção se refere a um oligonucleotídeo que compreende uma das sequências a seguir: (ttaggg) seq id no 1, (tagggt) seq id no. 2, (agggtt) seq id no. 3, (gggtta) seq id no. 4, (ggttag) seq id no. 5 ou (gttagg) seq id no. 6 ou uma sequência complementar deste ou um fragmento ou uma variante ou uma mistura deste para uso no tratamento e/ou prevenção de uma doença que compreende o alongamento alternativo de telômeros ou uma condição não cancerosa e composições farmacêuticas relativas e para composições farmacêuticas relativas e método.
BR112018001782A 2015-07-29 2016-07-29 oligonucleotídeo para uso no tratamento e/ou prevenção de uma doença que compreende o alongamento alternativo dos telômeros, oligonucleotídeo para uso no tratamento e/ou prevenção de uma condição não cancerosa associada à disfunção do telômero e composição farmacêutica BR112018001782A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15178809.8A EP3124609A1 (en) 2015-07-29 2015-07-29 Therapeutics oligonucleotides
PCT/EP2016/068162 WO2017017253A1 (en) 2015-07-29 2016-07-29 Therapeutic oligonucleotides

Publications (1)

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BR112018001782A2 true BR112018001782A2 (pt) 2018-09-18

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BR112018001782A BR112018001782A2 (pt) 2015-07-29 2016-07-29 oligonucleotídeo para uso no tratamento e/ou prevenção de uma doença que compreende o alongamento alternativo dos telômeros, oligonucleotídeo para uso no tratamento e/ou prevenção de uma condição não cancerosa associada à disfunção do telômero e composição farmacêutica

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US (2) US20180223279A1 (pt)
EP (1) EP3124609A1 (pt)
JP (1) JP7023834B2 (pt)
KR (1) KR102246814B1 (pt)
CN (1) CN108350456A (pt)
AU (1) AU2016300141B2 (pt)
BR (1) BR112018001782A2 (pt)
CA (1) CA2993128A1 (pt)
EA (1) EA039775B1 (pt)
MX (1) MX2018001126A (pt)
WO (1) WO2017017253A1 (pt)

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AU2016300141B2 (en) 2022-06-16
EP3124609A1 (en) 2017-02-01
US20180223279A1 (en) 2018-08-09
JP7023834B2 (ja) 2022-02-22
CN108350456A (zh) 2018-07-31
US20210087567A1 (en) 2021-03-25
EA039775B1 (ru) 2022-03-11
WO2017017253A1 (en) 2017-02-02
EA201890379A1 (ru) 2018-08-31
KR102246814B1 (ko) 2021-04-30
MX2018001126A (es) 2018-09-11
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AU2016300141A1 (en) 2018-03-01

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