BR112017012007B1 - Compostos orgânicos inibitórios de pde2, composições farmacêuticas compreendendo os ditos compostos e uso dos mesmos no tratamento de um distúrbio mediado por pde2 - Google Patents
Compostos orgânicos inibitórios de pde2, composições farmacêuticas compreendendo os ditos compostos e uso dos mesmos no tratamento de um distúrbio mediado por pde2 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
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- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
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- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201462088541P | 2014-12-06 | 2014-12-06 | |
| US62/088,541 | 2014-12-06 | ||
| PCT/US2015/064324 WO2016090380A1 (en) | 2014-12-06 | 2015-12-07 | Organic compounds |
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| BR112017012007A2 BR112017012007A2 (pt) | 2017-12-26 |
| BR112017012007B1 true BR112017012007B1 (pt) | 2022-11-01 |
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| BR112017012007-0A BR112017012007B1 (pt) | 2014-12-06 | 2015-12-07 | Compostos orgânicos inibitórios de pde2, composições farmacêuticas compreendendo os ditos compostos e uso dos mesmos no tratamento de um distúrbio mediado por pde2 |
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| Country | Link |
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| US (1) | US10300064B2 (OSRAM) |
| EP (1) | EP3226870B1 (OSRAM) |
| JP (1) | JP6608934B2 (OSRAM) |
| KR (1) | KR102557603B1 (OSRAM) |
| CN (1) | CN107205999B (OSRAM) |
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| MX (1) | MX371158B (OSRAM) |
| RU (1) | RU2709786C2 (OSRAM) |
| WO (1) | WO2016090380A1 (OSRAM) |
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| ES2906107T3 (es) | 2016-09-12 | 2022-04-13 | Intra Cellular Therapies Inc | Usos novedosos |
| DK3784661T3 (da) | 2018-04-25 | 2024-02-12 | Bayer Ag | Hidtil ukendte heteroaryl-triazol- og heteroaryl-tetrazol-forbindelser som pesticider |
| EP3870300B1 (en) * | 2018-10-23 | 2024-07-10 | Intra-Cellular Therapies, Inc. | Imidazo[1,5-a]pyrazine compounds as pde2 inhibitors |
| US12364695B2 (en) | 2020-06-02 | 2025-07-22 | Intra-Cellular Therapies, Inc. | Methods of treating inflammatory disease |
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2015
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| BR112017012007A2 (pt) | 2017-12-26 |
| IL252579A0 (en) | 2017-07-31 |
| CA2969594A1 (en) | 2016-06-09 |
| KR102557603B1 (ko) | 2023-07-19 |
| MX371158B (es) | 2020-01-20 |
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| AU2015357496A1 (en) | 2017-07-27 |
| RU2017123686A (ru) | 2019-01-09 |
| HK1243933A1 (zh) | 2018-07-27 |
| RU2017123686A3 (OSRAM) | 2019-07-17 |
| EP3226870A1 (en) | 2017-10-11 |
| WO2016090380A1 (en) | 2016-06-09 |
| CN107205999A (zh) | 2017-09-26 |
| MX2017007380A (es) | 2017-10-20 |
| IL252579B (en) | 2021-05-31 |
| HK1243936A1 (zh) | 2018-07-27 |
| EP3226870B1 (en) | 2019-09-25 |
| CN107205999B (zh) | 2021-08-03 |
| US10300064B2 (en) | 2019-05-28 |
| AU2015357496B2 (en) | 2019-09-19 |
| JP6608934B2 (ja) | 2019-11-20 |
| KR20170089000A (ko) | 2017-08-02 |
| RU2709786C2 (ru) | 2019-12-20 |
| JP2017536410A (ja) | 2017-12-07 |
| EP3226870A4 (en) | 2018-05-30 |
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