BR112017011174A2 - método e dispositivo para determinar o tempo de coagulação de uma amostra sanguínea e um vaso de reação - Google Patents

método e dispositivo para determinar o tempo de coagulação de uma amostra sanguínea e um vaso de reação

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Publication number
BR112017011174A2
BR112017011174A2 BR112017011174-8A BR112017011174A BR112017011174A2 BR 112017011174 A2 BR112017011174 A2 BR 112017011174A2 BR 112017011174 A BR112017011174 A BR 112017011174A BR 112017011174 A2 BR112017011174 A2 BR 112017011174A2
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BR
Brazil
Prior art keywords
blood sample
signal
sphere
reaction vessel
light beam
Prior art date
Application number
BR112017011174-8A
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English (en)
Other versions
BR112017011174B1 (pt
Inventor
Rousseau Alain
BRUTT Norbert
GUYON Bertrand
Original Assignee
Diagnostica Stago
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Filing date
Publication date
Application filed by Diagnostica Stago filed Critical Diagnostica Stago
Publication of BR112017011174A2 publication Critical patent/BR112017011174A2/pt
Publication of BR112017011174B1 publication Critical patent/BR112017011174B1/pt

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/10—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/10—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
    • G01N11/16—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N2011/006—Determining flow properties indirectly by measuring other parameters of the system
    • G01N2011/008—Determining flow properties indirectly by measuring other parameters of the system optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G01N21/5907—Densitometers
    • G01N2021/5969—Scanning of a tube, a cuvette, a volume of sample
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0058—Kind of property studied
    • G01N2203/0089—Biorheological properties

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

trata-se desse método de determinação que compreende as etapas que consistem em fornecer um vaso de reação (2) que contém uma amostra sanguínea (33) e uma esfera ferromagnética (11) colocada sobre uma via (9) fornecida no fundo do vaso de reação (2), submeter a esfera (11) a um campo magnético com a finalidade de mover a esfera ao longo da via (9) em um movimento oscilante, expor a amostra sanguínea a um feixe de luz incidente (36), detectar um feixe de luz (38) transmitido através do vaso de reação (2) e proveniente do feixe de luz incidente (36) de tal modo a fornecer um sinal de medição, executar um primeiro processamento do sinal de medição de tal modo a fornecer um primeiro sinal representativo da variação de pelo menos uma quantidade física representativa do movimento da esfera (11), executar um segundo processamento do sinal de medição de tal modo a fornecer um segundo sinal representativo da variação de pelo menos uma propriedade óptica da amostra sanguínea, determinar um primeiro valor do tempo de coagulação da amostra sanguínea a partir do primeiro sinal e determinar um segundo valor do tempo de coagulação da amostra sanguínea do segundo sinal.
BR112017011174-8A 2014-12-15 2015-12-09 Método e dispositivo para determinar o tempo de coagulação de uma amostra sanguínea e vaso de reação BR112017011174B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1462423 2014-12-15
FR1462423A FR3030048B1 (fr) 2014-12-15 2014-12-15 Procede et dispositif de determination du temps de coagulation d’un echantillon sanguin, et cuvette de reaction
PCT/FR2015/053399 WO2016097536A1 (fr) 2014-12-15 2015-12-09 Procédé et dispositif de détermination du temps de coagulation d'un échantillon sanguin, et cuvette de réaction

Publications (2)

Publication Number Publication Date
BR112017011174A2 true BR112017011174A2 (pt) 2018-02-27
BR112017011174B1 BR112017011174B1 (pt) 2023-10-24

Family

ID=52469191

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017011174-8A BR112017011174B1 (pt) 2014-12-15 2015-12-09 Método e dispositivo para determinar o tempo de coagulação de uma amostra sanguínea e vaso de reação

Country Status (13)

Country Link
US (1) US10605801B2 (pt)
EP (1) EP3234596B1 (pt)
JP (1) JP6696985B2 (pt)
KR (1) KR102377832B1 (pt)
CN (1) CN107003297B (pt)
AU (1) AU2015366041B2 (pt)
BR (1) BR112017011174B1 (pt)
CA (1) CA2968490C (pt)
ES (1) ES2829583T3 (pt)
FR (1) FR3030048B1 (pt)
MX (1) MX2017007791A (pt)
RU (1) RU2724335C2 (pt)
WO (1) WO2016097536A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3178556A1 (de) * 2015-12-10 2017-06-14 Holger Behnk Küvette und messverfahren
CN107505454A (zh) * 2017-06-23 2017-12-22 世纪亿康（天津）医疗科技发展有限公司 一种凝血及血小板功能检测的反应体系及其应用
RU2655774C1 (ru) * 2017-08-23 2018-05-29 Общество с ограниченной ответственностью МЛТ Кювета для коагулометра и устройство для определения времени свертывания текучего образца
US11998911B2 (en) 2018-07-29 2024-06-04 Koc Universitesi Microfluidic thromboelastometry instrument
WO2020133188A1 (zh) * 2018-12-28 2020-07-02 北京普利生仪器有限公司 一种凝血分析仪及其纤维蛋白原浓度检测方法
US10429377B1 (en) 2019-03-15 2019-10-01 Coagulation Sciences Llc Coagulation test device, system, and method of use
CN110631964B (zh) * 2019-06-28 2024-02-23 深圳迈瑞生物医疗电子股份有限公司 一种磁珠法检测方法和磁珠法检测装置
CN113994209A (zh) * 2019-07-31 2022-01-28 深圳迈瑞生物医疗电子股份有限公司 一种样本检测模块及样本分析仪
FR3100340B1 (fr) * 2019-09-04 2021-07-30 Arteion Dispositif d’entraînement pour un appareil d’analyse automatique pour diagnostic in vitro
CN112881234A (zh) * 2019-11-29 2021-06-01 深圳市帝迈生物技术有限公司 容纳结构、液体状态检测装置及其方法、样本分析仪
KR102444252B1 (ko) 2022-04-15 2022-09-16 김춘균 무용접트러스를 가지는 파이프의 홀가공장치
CN117233364B (zh) * 2023-11-16 2024-02-02 苏州思迈德生物科技有限公司 一种血栓弹力图的参数提取方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5014919B1 (pt) * 1968-06-17 1975-05-31
DE2741060C2 (de) * 1977-09-13 1982-06-24 Chemisch-pharmazeutische Industrie KG 6380 Bad Homburg Dr. Eduard Fresenius Verfahren und Vorrichtung zur Erfassung der Zustandsänderung einer Flüssigkeit
FR2634020B2 (fr) * 1987-12-30 1991-02-22 Serbio Cuvette pour analyseur biologique
FR2779827B1 (fr) * 1998-06-10 2000-08-11 Junior Instruments Appareil d'analyse automatique utilisable pour la determination du temps de coagulation du sang
RU2133955C1 (ru) * 1998-07-29 1999-07-27 Добровольский Николай Александрович Коагулометр шариковый
SE9902613D0 (sv) * 1999-07-07 1999-07-07 Jan Eric Litton Method and arrangement for measuring viscoelasticity of a Non-Newtonian fluid
RU2172483C2 (ru) * 2000-03-20 2001-08-20 Мухин Владимир Андреевич Способ и устройство определения свертываемости в пробах плазмы крови
FR2835616B1 (fr) * 2002-02-01 2005-02-11 Junior Instruments Dispositif pour l'analyse automatisee d'un echantillon liquide
FR2873447B1 (fr) * 2004-07-23 2007-09-28 Alain Michel Rousseau Analyseur automatique pluridisciplinaire pour le diagnostic in vitro
FR2896589B1 (fr) * 2006-01-25 2008-04-25 Biocode Hycel France Sa Sa Cuvette d'analyse polyvalente
CN2898812Y (zh) * 2006-05-17 2007-05-09 扬州大学 场致流变体粘度和刚度的一种测试装置
CN201034911Y (zh) * 2007-04-05 2008-03-12 张峰 便携式油液铁磁性磨粒量和粘度检测装置
US20110022429A1 (en) * 2007-12-21 2011-01-27 Positive Energy, Inc. Resource reporting
JP3150430U (ja) * 2009-02-03 2009-05-21 ビョコード イセル フランス ソシエテ アノニム 生体液分析用ユニットキュベット及び体外分析用自動分析装置
US8445287B2 (en) * 2009-02-14 2013-05-21 Wada, Inc. Method and apparatus for determining anticoagulant therapy factors
CN102640004B (zh) * 2009-12-04 2015-04-15 株式会社日立高新技术 血液凝固分析装置
FR2962221A1 (fr) * 2010-07-02 2012-01-06 Biofilm Control Procede de detection d'interactions moleculaires
FR2965622A1 (fr) * 2010-10-05 2012-04-06 Stago Diagnostica Cuvette de reaction pour appareil automatique d'analyse chimique ou biologique
JP5911443B2 (ja) * 2013-03-06 2016-04-27 シスメックス株式会社 血液凝固分析装置および血液凝固分析方法
CN203908909U (zh) * 2014-02-14 2014-10-29 中国石油大学(北京) 一种高压超低粘流体剪切粘度测量装置

Also Published As

Publication number Publication date
EP3234596B1 (fr) 2020-08-12
MX2017007791A (es) 2018-01-11
BR112017011174B1 (pt) 2023-10-24
FR3030048A1 (fr) 2016-06-17
KR20170094408A (ko) 2017-08-17
AU2015366041A1 (en) 2017-06-22
WO2016097536A1 (fr) 2016-06-23
RU2017123908A (ru) 2019-01-17
CA2968490C (fr) 2023-04-04
EP3234596A1 (fr) 2017-10-25
RU2724335C2 (ru) 2020-06-23
JP2017538941A (ja) 2017-12-28
AU2015366041B2 (en) 2022-03-10
KR102377832B1 (ko) 2022-03-22
JP6696985B2 (ja) 2020-05-20
FR3030048B1 (fr) 2016-12-23
RU2017123908A3 (pt) 2019-04-01
US10605801B2 (en) 2020-03-31
US20170370905A1 (en) 2017-12-28
CA2968490A1 (fr) 2016-06-23
CN107003297B (zh) 2019-08-20
ES2829583T3 (es) 2021-06-01
CN107003297A (zh) 2017-08-01

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