BR112017008734A2 - acelerador de produção de proteína tau e agente preventivo ou terapêutico e composição alimentícia preventiva ou terapêutica para doenças causadas por deficiência de proteína tau - Google Patents
acelerador de produção de proteína tau e agente preventivo ou terapêutico e composição alimentícia preventiva ou terapêutica para doenças causadas por deficiência de proteína tauInfo
- Publication number
- BR112017008734A2 BR112017008734A2 BR112017008734-0A BR112017008734A BR112017008734A2 BR 112017008734 A2 BR112017008734 A2 BR 112017008734A2 BR 112017008734 A BR112017008734 A BR 112017008734A BR 112017008734 A2 BR112017008734 A2 BR 112017008734A2
- Authority
- BR
- Brazil
- Prior art keywords
- tou
- protein
- preventive
- tau protein
- medicine
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 7
- 230000003449 preventive effect Effects 0.000 title abstract 7
- 239000003814 drug Substances 0.000 title abstract 5
- 239000003054 catalyst Substances 0.000 title 1
- 239000000470 constituent Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 230000014616 translation Effects 0.000 title 1
- 102000013498 tau Proteins Human genes 0.000 abstract 9
- 108010026424 tau Proteins Proteins 0.000 abstract 9
- 230000007812 deficiency Effects 0.000 abstract 6
- 239000000203 mixture Substances 0.000 abstract 3
- 229940124597 therapeutic agent Drugs 0.000 abstract 3
- 230000001225 therapeutic effect Effects 0.000 abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 241000361919 Metaphire sieboldi Species 0.000 abstract 1
- 229930014626 natural product Natural products 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/20—Natural extracts
- A23V2250/204—Animal extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
acelerador de produção de proteína tau e agente preventivo ou terapêutico e composição alimentícia preventiva ou terapêutica para doenças causadas por deficiência de proteína tau, sendo um objetivo da presente invenção fornecer um acelerador de produção de proteína tau que contém um produto natural como um ingrediente ativo; um agente preventivo ou terapêutico para uma doença causada por deficiência de proteína tau; e uma composição alimentícia preventiva ou terapêutica para uma doença causada por deficiência de proteína tau, sendo que são fornecidos: um acelerador de produção de proteína tau que contém um pó seco, um produto moído e/ou um extrato de uma minhoca como um ingrediente ativo; um agente preventivo ou terapêutico para uma doença causada por deficiência de proteína tau; e uma composição alimentícia preventiva ou terapêutica para uma doença causada por deficiência de proteína tau, sedno que a doença causada por deficiência de proteína tau é preferencialmente doença de alzheimer.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014-223977 | 2014-11-04 | ||
JP2014223977A JP6321521B2 (ja) | 2014-11-04 | 2014-11-04 | タウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物 |
PCT/JP2015/080934 WO2016072392A1 (ja) | 2014-11-04 | 2015-11-02 | タウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物 |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112017008734A2 true BR112017008734A2 (pt) | 2018-02-27 |
BR112017008734B1 BR112017008734B1 (pt) | 2021-11-23 |
Family
ID=55909117
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017008734-0A BR112017008734B1 (pt) | 2014-11-04 | 2015-11-02 | Acelerador de produção de proteína tau e agente preventivo ou terapêutico e composição alimentícia preventiva ou terapêutica para doenças causadas por deficiência de proteína tau |
Country Status (12)
Country | Link |
---|---|
US (2) | US10398740B2 (pt) |
EP (1) | EP3216456B1 (pt) |
JP (1) | JP6321521B2 (pt) |
KR (1) | KR101948913B1 (pt) |
CN (1) | CN106794199B (pt) |
AU (1) | AU2015344361B2 (pt) |
BR (1) | BR112017008734B1 (pt) |
CA (1) | CA2964316C (pt) |
PH (1) | PH12017500743A1 (pt) |
RU (1) | RU2742658C2 (pt) |
TW (1) | TWI689311B (pt) |
WO (1) | WO2016072392A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2017025019A (ja) * | 2015-07-21 | 2017-02-02 | Well Stone 有限会社 | アミロイドβ線維分解剤、アミロイドβの線維化に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物 |
AU2018240774B2 (en) | 2017-03-21 | 2023-01-12 | Well Stone Co. | Method for producing therapeutic agent for skin lesions, and therapeutic agent for skin lesions |
TW201929877A (zh) * | 2017-12-29 | 2019-08-01 | 大江生醫股份有限公司 | 地龍蛋白用於製造保護腦神經細胞醫藥組成物之用途 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5728007A (en) | 1980-07-29 | 1982-02-15 | Mitsuo Ishikura | Preparation of colorless, transparent and tasteless earthworm extract |
JPS59216572A (ja) | 1983-05-20 | 1984-12-06 | Yoichi Ishii | ミミズ蛋白及び脂質健康食品 |
KR900012617A (ko) | 1987-10-28 | 1990-09-01 | 요오이찌 이시이 | 혈전증 치료제 및 그 제조방법 |
JPH02215723A (ja) | 1989-02-15 | 1990-08-28 | Eimei:Kk | 血圧調節剤 |
RU2177784C2 (ru) | 1999-06-01 | 2002-01-10 | Пермское научно-производственное объединение "Биомед" | Энтеральный препарат, содержащий экстракт биомассы красного калифорнийского дождевого червя eisenia foetidae в виде таблеток "вермин" |
ITRM20050045A1 (it) * | 2005-02-02 | 2006-08-03 | Consiglio Nazionale Ricerche | Proteina isolata da eisenia foetida simile all'ngf umano e usi relativi. |
CN1873005A (zh) * | 2005-06-02 | 2006-12-06 | 中国科学院生物物理研究所 | 蚯蚓微管结合蛋白Tau、其编码基因及其应用 |
CN101095697A (zh) | 2006-06-28 | 2008-01-02 | 李振国 | 水蛭和/或地龙分子量5800道尔顿以下的提取物 |
CN101543512B (zh) * | 2008-03-28 | 2012-03-28 | 井石有限会社 | 蚯蚓干燥粉末的生产方法 |
KR20100137576A (ko) | 2008-04-24 | 2010-12-30 | 브리스톨-마이어스 스큅 컴퍼니 | 알츠하이머병을 포함하는 타우-관련 질병의 치료에서의 에포틸론 d의 용도 |
JP4886017B2 (ja) * | 2009-10-13 | 2012-02-29 | Well Stone 有限会社 | ミミズ乾燥粉末の製造方法 |
KR101198192B1 (ko) * | 2011-04-11 | 2012-11-12 | 웰 스톤 유겐가이샤 | 지렁이 건조 분말의 제조 방법 |
JP4808822B1 (ja) * | 2011-04-11 | 2011-11-02 | Well Stone 有限会社 | ミミズ乾燥粉末の製造方法 |
US9060958B2 (en) | 2011-07-29 | 2015-06-23 | Well Stone Co. | Tyrosinase inhibitor produced using dried earthworm powder, and method for producing same |
JP5856725B2 (ja) * | 2011-08-02 | 2016-02-10 | 和夫 酒井 | うつ病治療用または予防用医薬組成物 |
CN103251884B (zh) * | 2013-05-03 | 2015-02-18 | 杨文明 | 治疗阿尔茨海默病的中药及其制备方法和应用 |
CN103550537B (zh) * | 2013-11-10 | 2014-08-06 | 孟晓彬 | 一种治疗阿尔茨海默病的中药制剂及制备方法 |
CN106413722B (zh) | 2014-01-20 | 2020-08-04 | 井石有限会社 | 儿茶酚胺产生促进剂,起因于儿茶酚胺的缺乏的疾病的治疗药/预防药 |
-
2014
- 2014-11-04 JP JP2014223977A patent/JP6321521B2/ja active Active
-
2015
- 2015-11-02 CA CA2964316A patent/CA2964316C/en active Active
- 2015-11-02 EP EP15856572.1A patent/EP3216456B1/en active Active
- 2015-11-02 RU RU2017118158A patent/RU2742658C2/ru active
- 2015-11-02 US US15/523,767 patent/US10398740B2/en active Active
- 2015-11-02 WO PCT/JP2015/080934 patent/WO2016072392A1/ja active Application Filing
- 2015-11-02 AU AU2015344361A patent/AU2015344361B2/en active Active
- 2015-11-02 KR KR1020177015237A patent/KR101948913B1/ko active IP Right Grant
- 2015-11-02 BR BR112017008734-0A patent/BR112017008734B1/pt active IP Right Grant
- 2015-11-02 CN CN201580045874.1A patent/CN106794199B/zh active Active
- 2015-11-03 TW TW104136172A patent/TWI689311B/zh active
-
2017
- 2017-04-21 PH PH12017500743A patent/PH12017500743A1/en unknown
-
2019
- 2019-07-17 US US16/513,927 patent/US10576108B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
TW201630616A (zh) | 2016-09-01 |
RU2742658C2 (ru) | 2021-02-09 |
JP2016088877A (ja) | 2016-05-23 |
KR101948913B1 (ko) | 2019-02-15 |
US20170348357A1 (en) | 2017-12-07 |
EP3216456A1 (en) | 2017-09-13 |
RU2017118158A (ru) | 2018-12-05 |
RU2017118158A3 (pt) | 2019-06-06 |
US10576108B2 (en) | 2020-03-03 |
WO2016072392A8 (ja) | 2017-03-30 |
KR20170072348A (ko) | 2017-06-26 |
AU2015344361A1 (en) | 2017-06-15 |
WO2016072392A1 (ja) | 2016-05-12 |
CN106794199A (zh) | 2017-05-31 |
CN106794199B (zh) | 2021-03-23 |
AU2015344361B2 (en) | 2020-10-01 |
CA2964316C (en) | 2024-05-14 |
TWI689311B (zh) | 2020-04-01 |
PH12017500743A1 (en) | 2017-10-09 |
US10398740B2 (en) | 2019-09-03 |
BR112017008734B1 (pt) | 2021-11-23 |
JP6321521B2 (ja) | 2018-05-09 |
EP3216456A4 (en) | 2018-05-09 |
US20190365826A1 (en) | 2019-12-05 |
EP3216456B1 (en) | 2020-09-16 |
CA2964316A1 (en) | 2016-05-12 |
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