WO2016072392A8 - タウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物 - Google Patents

タウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物 Download PDF

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Publication number
WO2016072392A8
WO2016072392A8 PCT/JP2015/080934 JP2015080934W WO2016072392A8 WO 2016072392 A8 WO2016072392 A8 WO 2016072392A8 JP 2015080934 W JP2015080934 W JP 2015080934W WO 2016072392 A8 WO2016072392 A8 WO 2016072392A8
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WO
WIPO (PCT)
Prior art keywords
tau protein
therapeutic
diseases caused
preventive
food composition
Prior art date
Application number
PCT/JP2015/080934
Other languages
English (en)
French (fr)
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WO2016072392A1 (ja
Inventor
陽一 石井
隆行 根本
猛 岡本
Original Assignee
Well Stone 有限会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CN201580045874.1A priority Critical patent/CN106794199B/zh
Priority to AU2015344361A priority patent/AU2015344361B2/en
Priority to RU2017118158A priority patent/RU2742658C2/ru
Priority to KR1020177015237A priority patent/KR101948913B1/ko
Priority to EP15856572.1A priority patent/EP3216456B1/en
Priority to BR112017008734-0A priority patent/BR112017008734B1/pt
Application filed by Well Stone 有限会社 filed Critical Well Stone 有限会社
Priority to CA2964316A priority patent/CA2964316C/en
Priority to US15/523,767 priority patent/US10398740B2/en
Publication of WO2016072392A1 publication Critical patent/WO2016072392A1/ja
Publication of WO2016072392A8 publication Critical patent/WO2016072392A8/ja
Priority to PH12017500743A priority patent/PH12017500743A1/en
Priority to US16/513,927 priority patent/US10576108B2/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/322Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00Food ingredients
    • A23V2250/20Natural extracts
    • A23V2250/204Animal extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

天然物を有効成分として含有するタウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬、タウ蛋白の欠乏に起因する疾患の治療用・予防用食品組成物を提供することにある。ミミズの乾燥粉末、摩砕物及び/又は抽出物を有効成分として含有するタウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬、タウ蛋白の欠乏に起因する疾患の治療用・予防用食品組成物である。前記タウ蛋白の欠乏に起因する疾患は、アルツハイマー病であることが好ましい。
PCT/JP2015/080934 2014-11-04 2015-11-02 タウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物 WO2016072392A1 (ja)

Priority Applications (10)

Application Number Priority Date Filing Date Title
AU2015344361A AU2015344361B2 (en) 2014-11-04 2015-11-02 Tau protein production accelerator, and therapeutic or preventive agent and therapeutic or preventive food composition for diseases caused by tau protein deficiency
RU2017118158A RU2742658C2 (ru) 2014-11-04 2015-11-02 Средство, стимулирующее продукцию тау-белка, и терапевтическое или профилактическое средство и терапевтическая или профилактическая пищевая композиция, предназначенные для лечения заболеваний, вызванных дефицитом тау-белка
KR1020177015237A KR101948913B1 (ko) 2014-11-04 2015-11-02 타우 단백질 생산 촉진제, 타우 단백질의 결핍에 기인한 질환의 치료약·예방약 및 치료용·예방용 식품 조성물
EP15856572.1A EP3216456B1 (en) 2014-11-04 2015-11-02 Tau protein production accelerator, and therapeutic or preventive agent for diseases caused by tau protein deficiency
BR112017008734-0A BR112017008734B1 (pt) 2014-11-04 2015-11-02 Acelerador de produção de proteína tau e agente preventivo ou terapêutico e composição alimentícia preventiva ou terapêutica para doenças causadas por deficiência de proteína tau
CN201580045874.1A CN106794199B (zh) 2014-11-04 2015-11-02 Tau蛋白产生促进剂、起因于缺乏Tau蛋白的疾病的治疗药/预防药
CA2964316A CA2964316C (en) 2014-11-04 2015-11-02 Tau protein production accelerator, and therapeutic or preventive agent and therapeutic or preventive food composition for diseases caused by tau protein deficiency
US15/523,767 US10398740B2 (en) 2014-11-04 2015-11-02 Tau protein production accelerator, and therapeutic or preventive agent and therapeutic or preventive food composition for diseases caused by tau protein deficiency
PH12017500743A PH12017500743A1 (en) 2014-11-04 2017-04-21 Tau protein production accelerator, and therapeutic or preventive agent and therapeutic or preventive food composition for diseases caused by tau protein deficiency
US16/513,927 US10576108B2 (en) 2014-11-04 2019-07-17 Tau protein production accelerator, and therapeutic or preventive agent and therapeutic or preventive food composition for diseases caused by tau protein deficiency

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014-223977 2014-11-04
JP2014223977A JP6321521B2 (ja) 2014-11-04 2014-11-04 タウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US15/523,767 A-371-Of-International US10398740B2 (en) 2014-11-04 2015-11-02 Tau protein production accelerator, and therapeutic or preventive agent and therapeutic or preventive food composition for diseases caused by tau protein deficiency
US16/513,927 Division US10576108B2 (en) 2014-11-04 2019-07-17 Tau protein production accelerator, and therapeutic or preventive agent and therapeutic or preventive food composition for diseases caused by tau protein deficiency

Publications (2)

Publication Number Publication Date
WO2016072392A1 WO2016072392A1 (ja) 2016-05-12
WO2016072392A8 true WO2016072392A8 (ja) 2017-03-30

Family

ID=55909117

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2015/080934 WO2016072392A1 (ja) 2014-11-04 2015-11-02 タウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物

Country Status (12)

Country Link
US (2) US10398740B2 (ja)
EP (1) EP3216456B1 (ja)
JP (1) JP6321521B2 (ja)
KR (1) KR101948913B1 (ja)
CN (1) CN106794199B (ja)
AU (1) AU2015344361B2 (ja)
BR (1) BR112017008734B1 (ja)
CA (1) CA2964316C (ja)
PH (1) PH12017500743A1 (ja)
RU (1) RU2742658C2 (ja)
TW (1) TWI689311B (ja)
WO (1) WO2016072392A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017025019A (ja) * 2015-07-21 2017-02-02 Well Stone 有限会社 アミロイドβ線維分解剤、アミロイドβの線維化に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物
CN110191715B (zh) 2017-03-21 2020-11-10 井石有限会社 皮肤损伤治疗剂的制造方法及皮肤损伤治疗剂
TW201929877A (zh) * 2017-12-29 2019-08-01 大江生醫股份有限公司 地龍蛋白用於製造保護腦神經細胞醫藥組成物之用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5728007A (en) * 1980-07-29 1982-02-15 Mitsuo Ishikura Preparation of colorless, transparent and tasteless earthworm extract
JPS59216572A (ja) * 1983-05-20 1984-12-06 Yoichi Ishii ミミズ蛋白及び脂質健康食品
KR900012617A (ko) * 1987-10-28 1990-09-01 요오이찌 이시이 혈전증 치료제 및 그 제조방법
JPH02215723A (ja) * 1989-02-15 1990-08-28 Eimei:Kk 血圧調節剤
RU2177784C2 (ru) 1999-06-01 2002-01-10 Пермское научно-производственное объединение "Биомед" Энтеральный препарат, содержащий экстракт биомассы красного калифорнийского дождевого червя eisenia foetidae в виде таблеток "вермин"
ITRM20050045A1 (it) * 2005-02-02 2006-08-03 Consiglio Nazionale Ricerche Proteina isolata da eisenia foetida simile all'ngf umano e usi relativi.
CN1873005A (zh) * 2005-06-02 2006-12-06 中国科学院生物物理研究所 蚯蚓微管结合蛋白Tau、其编码基因及其应用
CN101095697A (zh) * 2006-06-28 2008-01-02 李振国 水蛭和/或地龙分子量5800道尔顿以下的提取物
CN101543512B (zh) * 2008-03-28 2012-03-28 井石有限会社 蚯蚓干燥粉末的生产方法
PL2276485T3 (pl) * 2008-04-24 2014-12-31 Bristol Myers Squibb Co Stosowanie epotilonu D w leczeniu chorób związanych z Tau, w tym choroby Alzheimera
JP4886017B2 (ja) * 2009-10-13 2012-02-29 Well Stone 有限会社 ミミズ乾燥粉末の製造方法
JP4808822B1 (ja) 2011-04-11 2011-11-02 Well Stone 有限会社 ミミズ乾燥粉末の製造方法
KR101198192B1 (ko) 2011-04-11 2012-11-12 웰 스톤 유겐가이샤 지렁이 건조 분말의 제조 방법
CN103702661B (zh) 2011-07-29 2015-10-07 井石有限会社 使用了蚯蚓干燥粉末的酪氨酸酶抑制剂及其制造方法
JP5856725B2 (ja) * 2011-08-02 2016-02-10 和夫 酒井 うつ病治療用または予防用医薬組成物
CN103251884B (zh) * 2013-05-03 2015-02-18 杨文明 治疗阿尔茨海默病的中药及其制备方法和应用
CN103550537B (zh) * 2013-11-10 2014-08-06 孟晓彬 一种治疗阿尔茨海默病的中药制剂及制备方法
BR112016014981B1 (pt) * 2014-01-20 2021-10-13 Well Stone Co Acelerador de produção de catecolamina e agente preventivo e terapêutico e composição alimentícia preventiva e terapêutica para doenças causadas por deficiência de catecolamina

Also Published As

Publication number Publication date
AU2015344361A1 (en) 2017-06-15
TW201630616A (zh) 2016-09-01
JP2016088877A (ja) 2016-05-23
CA2964316C (en) 2024-05-14
EP3216456B1 (en) 2020-09-16
AU2015344361B2 (en) 2020-10-01
WO2016072392A1 (ja) 2016-05-12
TWI689311B (zh) 2020-04-01
CN106794199A (zh) 2017-05-31
US20170348357A1 (en) 2017-12-07
US20190365826A1 (en) 2019-12-05
EP3216456A1 (en) 2017-09-13
BR112017008734B1 (pt) 2021-11-23
CA2964316A1 (en) 2016-05-12
KR101948913B1 (ko) 2019-02-15
EP3216456A4 (en) 2018-05-09
US10398740B2 (en) 2019-09-03
PH12017500743A1 (en) 2017-10-09
BR112017008734A2 (ja) 2018-02-27
RU2017118158A3 (ja) 2019-06-06
CN106794199B (zh) 2021-03-23
JP6321521B2 (ja) 2018-05-09
KR20170072348A (ko) 2017-06-26
RU2017118158A (ru) 2018-12-05
RU2742658C2 (ru) 2021-02-09
US10576108B2 (en) 2020-03-03

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