BR112017008097B1 - Método para tratar condições oculares - Google Patents

Método para tratar condições oculares Download PDF

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Publication number
BR112017008097B1
BR112017008097B1 BR112017008097-4A BR112017008097A BR112017008097B1 BR 112017008097 B1 BR112017008097 B1 BR 112017008097B1 BR 112017008097 A BR112017008097 A BR 112017008097A BR 112017008097 B1 BR112017008097 B1 BR 112017008097B1
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BR
Brazil
Prior art keywords
nicotinic acetylcholine
acetylcholine receptor
receptor agonist
another embodiment
administered
Prior art date
Application number
BR112017008097-4A
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English (en)
Portuguese (pt)
Other versions
BR112017008097A2 (pt
Inventor
Ackermann Douglas Michael, Jr.
Loudin James
Mandell Kenneth J
Original Assignee
Oyster Point Pharma, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55748136&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112017008097(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Oyster Point Pharma, Inc filed Critical Oyster Point Pharma, Inc
Priority to BR122022025737-2A priority Critical patent/BR122022025737B1/pt
Publication of BR112017008097A2 publication Critical patent/BR112017008097A2/pt
Publication of BR112017008097B1 publication Critical patent/BR112017008097B1/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Emergency Medicine (AREA)
BR112017008097-4A 2014-10-20 2015-10-19 Método para tratar condições oculares BR112017008097B1 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122022025737-2A BR122022025737B1 (pt) 2014-10-20 2015-10-19 Método para tratar condições oculares

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462066280P 2014-10-20 2014-10-20
US62/066,280 2014-10-20
US201562100844P 2015-01-07 2015-01-07
US62/100,844 2015-01-07
PCT/US2015/056273 WO2016064759A1 (en) 2014-10-20 2015-10-19 Methods of treating ocular conditions

Publications (2)

Publication Number Publication Date
BR112017008097A2 BR112017008097A2 (pt) 2018-02-20
BR112017008097B1 true BR112017008097B1 (pt) 2023-03-28

Family

ID=55748136

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112017008097-4A BR112017008097B1 (pt) 2014-10-20 2015-10-19 Método para tratar condições oculares
BR122022025737-2A BR122022025737B1 (pt) 2014-10-20 2015-10-19 Método para tratar condições oculares

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR122022025737-2A BR122022025737B1 (pt) 2014-10-20 2015-10-19 Método para tratar condições oculares

Country Status (21)

Country Link
US (14) US9597284B2 (OSRAM)
EP (3) EP3848028B9 (OSRAM)
JP (3) JP6873906B2 (OSRAM)
KR (2) KR102511955B1 (OSRAM)
CN (3) CN107106542B (OSRAM)
AU (2) AU2015336216B2 (OSRAM)
BR (2) BR112017008097B1 (OSRAM)
CA (1) CA2965129C (OSRAM)
DK (2) DK3209295T4 (OSRAM)
EA (1) EA035335B1 (OSRAM)
ES (2) ES2986830T3 (OSRAM)
FI (1) FI3848028T3 (OSRAM)
IL (3) IL293188B2 (OSRAM)
MX (2) MX392383B (OSRAM)
MY (1) MY186870A (OSRAM)
PH (1) PH12017500602A1 (OSRAM)
PL (1) PL3848028T3 (OSRAM)
PT (2) PT3848028T (OSRAM)
SG (2) SG10202011669PA (OSRAM)
WO (1) WO2016064759A1 (OSRAM)
ZA (1) ZA201703467B (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
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EP3848028B9 (en) 2014-10-20 2024-10-16 Oyster Point Pharma, Inc. Methods of treating ocular conditions
DK3439661T3 (da) * 2016-04-07 2021-10-18 Oyster Point Pharma Inc Fremgangsmåder til behandling af øjenlidelser
TW202019424A (zh) * 2018-07-10 2020-06-01 美商奧伊斯特普安生物製藥公司 治療眼部症狀之方法
EP3820443A1 (en) 2018-07-10 2021-05-19 Oyster Point Pharma, Inc. Combinations of positive allosteric modulators and nicotinic acetylcholine receptor agonists for treating ocular conditions
ES3039903T3 (en) 2020-04-28 2025-10-27 Oyster Point Pharma Inc Local administration of nicotinic acetylcholine receptor agonists for the inhibition of coronavirus infections
WO2025037323A1 (en) * 2023-08-12 2025-02-20 Pavan Kumar Kothapuvari Pharmaceutical compositions for treatment of dry eye disease and associated disorders
DE102023208057A1 (de) * 2023-08-23 2025-02-27 Ursapharm Arzneimittel Gmbh Ophthalmologische zusammensetzung enthaltend mindestens einen nikotinischen acetylcholinrezeptor-agonist zur topischen applikation am auge bei der prävention oder behandlung von entzündungen am auge

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TW202019424A (zh) 2018-07-10 2020-06-01 美商奧伊斯特普安生物製藥公司 治療眼部症狀之方法
EP3820443A1 (en) 2018-07-10 2021-05-19 Oyster Point Pharma, Inc. Combinations of positive allosteric modulators and nicotinic acetylcholine receptor agonists for treating ocular conditions

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ES2848977T3 (es) 2021-08-13
US10456396B2 (en) 2019-10-29
EA201790893A1 (ru) 2018-01-31
EP3848028B9 (en) 2024-10-16
EP3848028A1 (en) 2021-07-14
US20230226053A1 (en) 2023-07-20
US20240173318A1 (en) 2024-05-30
US20170239244A1 (en) 2017-08-24
CN111956650B (zh) 2024-06-04
EA035335B1 (ru) 2020-05-28
JP6873906B2 (ja) 2021-05-19
US11903941B2 (en) 2024-02-20
IL318427A (en) 2025-03-01
US20250275963A1 (en) 2025-09-04
US9532944B2 (en) 2017-01-03
US9597284B2 (en) 2017-03-21
IL251769B (en) 2022-06-01
EP3209295A1 (en) 2017-08-30
JP7502404B2 (ja) 2024-06-18
US20230226052A1 (en) 2023-07-20
BR112017008097A2 (pt) 2018-02-20
DK3848028T5 (da) 2025-01-20
CN111956803A (zh) 2020-11-20
PL3848028T3 (pl) 2024-11-18
EP3209295B1 (en) 2020-12-09
MX392383B (es) 2025-03-24
CN107106542A (zh) 2017-08-29
MX2022005888A (es) 2022-06-14
DK3209295T4 (da) 2024-02-26
MY186870A (en) 2021-08-26
EP4413974A2 (en) 2024-08-14
WO2016064759A1 (en) 2016-04-28
IL293188B2 (en) 2025-06-01
CN111956803B (zh) 2025-10-31
KR102511955B1 (ko) 2023-03-22
ES2986830T3 (es) 2024-11-12
PT3848028T (pt) 2024-09-20
PT3209295T (pt) 2021-02-05
CN111956650A (zh) 2020-11-20
CA2965129C (en) 2024-03-12
US20160106746A1 (en) 2016-04-21
US20220233528A1 (en) 2022-07-28
CN107106542B (zh) 2020-05-08
AU2020213351B2 (en) 2023-04-06
IL251769A0 (en) 2017-06-29
DK3209295T3 (da) 2021-03-01
US11224598B2 (en) 2022-01-18
US11903943B2 (en) 2024-02-20
US20160106744A1 (en) 2016-04-21
CA2965129A1 (en) 2016-04-28
US20160106745A1 (en) 2016-04-21
JP2021038250A (ja) 2021-03-11
AU2015336216A1 (en) 2017-06-08
EP3209295B2 (en) 2023-12-06
US20250235449A1 (en) 2025-07-24
KR20170086040A (ko) 2017-07-25
EP4413974A3 (en) 2024-10-09
EP3209295A4 (en) 2018-05-23
JP2017531044A (ja) 2017-10-19
SG10202011669PA (en) 2020-12-30
EP3848028B1 (en) 2024-05-29
KR20230042144A (ko) 2023-03-27
US20200246336A1 (en) 2020-08-06
JP2023024574A (ja) 2023-02-16
ZA201703467B (en) 2023-12-20
ES2848977T5 (es) 2024-06-06
PH12017500602A1 (en) 2017-09-04
DK3848028T3 (da) 2024-08-26
US20230226054A1 (en) 2023-07-20
US9504644B2 (en) 2016-11-29
AU2015336216B2 (en) 2020-05-21
JP7257371B2 (ja) 2023-04-13
IL293188B1 (en) 2025-02-01
US20250255865A1 (en) 2025-08-14
SG11201703135XA (en) 2017-05-30
BR122022025737B1 (pt) 2023-12-26
AU2020213351A1 (en) 2020-08-27
IL293188A (en) 2022-07-01
US11903942B2 (en) 2024-02-20
US11911380B2 (en) 2024-02-27
FI3848028T3 (fi) 2024-08-21
MX2017005064A (es) 2018-02-23
US20160106665A1 (en) 2016-04-21
KR102601505B1 (ko) 2023-11-14
US12576080B2 (en) 2026-03-17
US9504645B2 (en) 2016-11-29

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