BR112017004952B1 - Unidade e método de processamento enzimático para processamento enzimático à base de fluxo contínuo de moléculas orgânicas, navio equipado com a unidade, método de fabricação de uma unidade de processamento enzimático modular para processamento enzimático de uma mistura reacional - Google Patents

Unidade e método de processamento enzimático para processamento enzimático à base de fluxo contínuo de moléculas orgânicas, navio equipado com a unidade, método de fabricação de uma unidade de processamento enzimático modular para processamento enzimático de uma mistura reacional Download PDF

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Publication number
BR112017004952B1
BR112017004952B1 BR112017004952-0A BR112017004952A BR112017004952B1 BR 112017004952 B1 BR112017004952 B1 BR 112017004952B1 BR 112017004952 A BR112017004952 A BR 112017004952A BR 112017004952 B1 BR112017004952 B1 BR 112017004952B1
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BR
Brazil
Prior art keywords
turbulence
unit
reaction mixture
enzymatic
enzymatic processing
Prior art date
Application number
BR112017004952-0A
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English (en)
Portuguese (pt)
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BR112017004952A2 (pt
Inventor
Olav Asle Djupevag
Torstein FRANTZEN
Original Assignee
Alkymar As
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Publication date
Application filed by Alkymar As filed Critical Alkymar As
Publication of BR112017004952A2 publication Critical patent/BR112017004952A2/pt
Publication of BR112017004952B1 publication Critical patent/BR112017004952B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/18—Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4331—Mixers with bended, curved, coiled, wounded mixing tubes or comprising elements for bending the flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4333—Mixers with scallop-shaped tubes or surfaces facing each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4338—Mixers with a succession of converging-diverging cross-sections, i.e. undulating cross-section
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B63—SHIPS OR OTHER WATERBORNE VESSELS; RELATED EQUIPMENT
    • B63B—SHIPS OR OTHER WATERBORNE VESSELS; EQUIPMENT FOR SHIPPING 
    • B63B35/00—Vessels or similar floating structures specially adapted for specific purposes and not otherwise provided for
    • B63B35/14—Fishing vessels
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/02—Apparatus for enzymology or microbiology with agitation means; with heat exchange means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/16—Apparatus for enzymology or microbiology containing, or adapted to contain, solid media
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/40—Apparatus specially designed for the use of free, immobilised, or carrier-bound enzymes, e.g. apparatus containing a fluidised bed of immobilised enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/16—Vibrating; Shaking; Tilting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/22—Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/44—Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0418—Geometrical information
    • B01F2215/0431—Numerical size values, e.g. diameter of a hole or conduit, area, volume, length, width, or ratios thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0436—Operational information
    • B01F2215/0477—Numerical time values
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0436—Operational information
    • B01F2215/0481—Numerical speed values

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Combustion & Propulsion (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Ocean & Marine Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Accessories For Mixers (AREA)
  • Fats And Perfumes (AREA)
BR112017004952-0A 2014-09-15 2015-09-14 Unidade e método de processamento enzimático para processamento enzimático à base de fluxo contínuo de moléculas orgânicas, navio equipado com a unidade, método de fabricação de uma unidade de processamento enzimático modular para processamento enzimático de uma mistura reacional BR112017004952B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1416283.8A GB201416283D0 (en) 2014-09-15 2014-09-15 Enzymatic processing plant and method of enzymatic processing
GB1416283.8 2014-09-15
PCT/EP2015/070942 WO2016041896A1 (en) 2014-09-15 2015-09-14 Enzymatic processing plant and method of enzymatic processing

Publications (2)

Publication Number Publication Date
BR112017004952A2 BR112017004952A2 (pt) 2017-12-05
BR112017004952B1 true BR112017004952B1 (pt) 2022-08-16

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017004952-0A BR112017004952B1 (pt) 2014-09-15 2015-09-14 Unidade e método de processamento enzimático para processamento enzimático à base de fluxo contínuo de moléculas orgânicas, navio equipado com a unidade, método de fabricação de uma unidade de processamento enzimático modular para processamento enzimático de uma mistura reacional

Country Status (13)

Country Link
US (1) US11286448B2 (enExample)
EP (1) EP3194060A1 (enExample)
JP (2) JP2017529875A (enExample)
CN (1) CN107073415B (enExample)
BR (1) BR112017004952B1 (enExample)
CA (1) CA2961120C (enExample)
CL (2) CL2017000612A1 (enExample)
EC (1) ECSP17018111A (enExample)
GB (1) GB201416283D0 (enExample)
PE (1) PE20171036A1 (enExample)
RU (1) RU2717506C2 (enExample)
WO (1) WO2016041896A1 (enExample)
ZA (1) ZA201702310B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2548386A (en) 2016-03-17 2017-09-20 Alkymar As Mixing and processing apparatus
GB201807246D0 (en) 2018-05-02 2018-06-13 Biomega Group AS Enzymatic method
CA3115258A1 (en) * 2018-10-08 2020-04-16 Boehringer Ingelheim International Gmbh Continuous flow reactor for viral inactivation
CA3155325A1 (en) * 2019-11-04 2021-05-14 Parker-Hannifin Corporation Inline mixer device, methods of mixing, and methods of making an inline mixer device
JPWO2022196331A1 (enExample) * 2021-03-18 2022-09-22
CN113090946B (zh) * 2021-04-06 2022-04-05 西南石油大学 一种促进掺氢天然气管道内天然气与氢气混合的蚌式管道结构

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH606436A5 (enExample) * 1974-09-19 1978-10-31 Giovanola Freres Sa
US4434229A (en) * 1979-05-21 1984-02-28 Matsushita Electric Industrial Co., Ltd. Enzyme immobilization with an immobilizing reagent in vapor phase
JPS6248375A (ja) * 1985-08-23 1987-03-03 Lion Corp 固定化酵素反応器
FR2698559B1 (fr) * 1992-11-30 1995-02-17 Univ Nantes Echangeur mélangeur à effet de convection chaotique.
US6258575B1 (en) * 1998-11-26 2001-07-10 Kao Corporation Hydrolyzing fats and oils using an immobilized enzyme column and substrate-feeding chamber that separates phases
CN2540213Y (zh) * 2002-04-17 2003-03-19 徐立群 列管式静态混合器
DK175501B1 (da) * 2002-12-02 2004-11-15 Green Earth Anlæg og fremgangsmåde til kontinuerlig hydrolyse af et proteinholdigt animalsk eller vegetabilsk råmateriale
JP2006513851A (ja) * 2003-02-26 2006-04-27 デグレマン ソシエテ アノニム 特に懸濁汚染物を含む液状排出物の処理方法およびシステム
CN103203195A (zh) * 2003-10-29 2013-07-17 风神有限公司 气体扩散处理装置
EP1771385B1 (de) 2004-07-26 2010-09-15 Frank Reiner Kolb Hydrodynamische homogenisation
US20060051448A1 (en) * 2004-09-03 2006-03-09 Charles Schryver Extruded tubing for mixing reagents
JP4677969B2 (ja) * 2006-10-06 2011-04-27 株式会社日立プラントテクノロジー マイクロリアクタ
WO2009113609A1 (ja) * 2008-03-14 2009-09-17 Dic株式会社 エポキシ（メタ）アクリレートの製造方法
FR2938268B1 (fr) * 2008-11-12 2013-03-29 Centre Nat Rech Scient Procede de culture de micro-organismes, bioreacteur de mise en oeuvre et procede de fabrication d'un tel bioreacteur
RU2490323C1 (ru) * 2012-06-25 2013-08-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Санкт-Петербургский государственный технологический институт (технический университет)" Микробиореактор и способ его эксплуатации

Also Published As

Publication number Publication date
EP3194060A1 (en) 2017-07-26
CL2019002098A1 (es) 2019-10-25
JP7050120B2 (ja) 2022-04-07
BR112017004952A2 (pt) 2017-12-05
GB201416283D0 (en) 2014-10-29
US20170247649A1 (en) 2017-08-31
WO2016041896A1 (en) 2016-03-24
US11286448B2 (en) 2022-03-29
RU2017112689A (ru) 2018-10-17
RU2717506C2 (ru) 2020-03-23
RU2017112689A3 (enExample) 2019-08-13
CL2017000612A1 (es) 2017-12-22
CN107073415A (zh) 2017-08-18
JP2020179395A (ja) 2020-11-05
JP2017529875A (ja) 2017-10-12
CA2961120A1 (en) 2016-03-24
ZA201702310B (en) 2019-09-25
ECSP17018111A (es) 2017-06-30
CN107073415B (zh) 2021-02-05
PE20171036A1 (es) 2017-07-17
CA2961120C (en) 2023-09-26

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/09/2015, OBSERVADAS AS CONDICOES LEGAIS