BR112017004761A2 - método para preparar um diéster de astaxantina, uso não terapêutico de um diéster, e, diéster - Google Patents
método para preparar um diéster de astaxantina, uso não terapêutico de um diéster, e, diésterInfo
- Publication number
- BR112017004761A2 BR112017004761A2 BR112017004761A BR112017004761A BR112017004761A2 BR 112017004761 A2 BR112017004761 A2 BR 112017004761A2 BR 112017004761 A BR112017004761 A BR 112017004761A BR 112017004761 A BR112017004761 A BR 112017004761A BR 112017004761 A2 BR112017004761 A2 BR 112017004761A2
- Authority
- BR
- Brazil
- Prior art keywords
- diester
- therapeutic use
- astaxanthin
- formula
- preparing
- Prior art date
Links
- 150000005690 diesters Chemical class 0.000 title abstract 4
- 230000001225 therapeutic effect Effects 0.000 title abstract 3
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 title abstract 2
- 229940022405 astaxanthin Drugs 0.000 title abstract 2
- 235000013793 astaxanthin Nutrition 0.000 title abstract 2
- 239000001168 astaxanthin Substances 0.000 title abstract 2
- -1 astaxanthin diester Chemical class 0.000 title abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 abstract 1
- 150000001514 astaxanthins Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
a invenção refere-se a um método para produzir ésteres de astaxantina de fórmula 1 econômico, ambientalmente amigável e que conserva recursos, em que a astaxantina de fórmula 2 é duplamente esterificada com cloretos de ácido graxo de fórmula geral 3. para este efeito, os compostos 2 e 3 são feitos reagir em um solvente orgânico na presença de uma base contendo nitrogênio de fórmula geral 4. a invenção refere-se ainda ao uso não terapêutico do diéster 1, em que r representa um resíduo que é selecionado do grupo que consiste de alquila c13-c19, alquenila c13-c19, alquidienila c13-c19 e alquitrienilena c13-c19, na alimentação de seres humanos ou animais e ao diéster 1 produzido de acordo com o método, para uso terapêutico como uma medicação e como ingrediente para uma preparação médica.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14184483 | 2014-09-11 | ||
| PCT/EP2015/068445 WO2016037785A1 (de) | 2014-09-11 | 2015-08-11 | Verfahren zur herstellung von astaxanthinestern |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112017004761A2 true BR112017004761A2 (pt) | 2017-12-05 |
Family
ID=51542186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112017004761A BR112017004761A2 (pt) | 2014-09-11 | 2015-08-11 | método para preparar um diéster de astaxantina, uso não terapêutico de um diéster, e, diéster |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20170305849A1 (pt) |
| EP (1) | EP3191448A1 (pt) |
| JP (1) | JP2017526712A (pt) |
| KR (1) | KR20170052630A (pt) |
| CN (1) | CN106687443A (pt) |
| AU (1) | AU2015314580A1 (pt) |
| BR (1) | BR112017004761A2 (pt) |
| CA (1) | CA2958386A1 (pt) |
| MX (1) | MX2017003237A (pt) |
| RU (1) | RU2017112051A (pt) |
| WO (1) | WO2016037785A1 (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2948605C (en) | 2014-05-20 | 2019-12-24 | Fuji Chemical Industries Co., Ltd. | Carotenoid derivative, pharmaceutically acceptable salt thereof, or pharmaceutically acceptable ester or amide thereof |
| DK3274465T3 (da) | 2015-03-26 | 2022-10-24 | Basf Se | Biokatalytisk fremstilling af l-fucose |
| US10538470B2 (en) | 2015-05-08 | 2020-01-21 | BASF Agro B.V. | Process for the preparation of limonene-4-ol |
| CN107635982A (zh) | 2015-05-08 | 2018-01-26 | 巴斯夫农业公司 | 制备萜品油烯环氧化物的方法 |
| US10315975B2 (en) | 2015-07-10 | 2019-06-11 | Basf Se | Method for the hydroformylation of 2-substituted butadienes and the production of secondary products thereof, especially ambrox |
| WO2017140909A1 (de) | 2016-02-19 | 2017-08-24 | Basf Se | Enzymatische zyklisierung von homofarnesylsäure |
| BR112018076043B1 (pt) | 2016-06-15 | 2023-09-26 | Basf Agro B.V | Processo de epoxidação de alqueno tetrassubstituído e uso de agente oxidante |
| WO2017215929A1 (en) | 2016-06-15 | 2017-12-21 | BASF Agro B.V. | Process for the epoxidation of a tetrasubstituted alkene |
| CN108250119A (zh) * | 2018-03-07 | 2018-07-06 | 广州立达尔生物科技股份有限公司 | 从侧金盏花油树脂中提纯制备高含量天然虾青素酯的方法 |
| KR20240034947A (ko) | 2022-09-07 | 2024-03-15 | 전북대학교산학협력단 | 크립토캅신과 루테인을 주성분으로 하는 복합 추출물 및 그의 제조방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07300421A (ja) * | 1994-04-28 | 1995-11-14 | Itano Reitou Kk | 抗炎症剤 |
| DE10049271A1 (de) | 2000-09-28 | 2002-04-11 | Basf Ag | Verfahren zur katalytischen Reduktion von Alkinverbindungen |
| DE10140180A1 (de) | 2001-08-22 | 2003-03-06 | Basf Ag | Verfahren zur selektiven Reduktion von Alkinverbindungen |
| JP4420675B2 (ja) | 2002-02-06 | 2010-02-24 | ディーエスエム アイピー アセッツ ビー．ブイ． | アスタキサンチンエステル |
| ES2223270B1 (es) | 2003-04-10 | 2006-04-16 | Carotenoid Technologies, S.A. | Procedimiento para la sintesis de astaxantina. |
| CN101386879A (zh) * | 2008-10-30 | 2009-03-18 | 广州立达尔生物科技有限公司 | 一种制备虾青素酯的方法 |
| TWI501946B (zh) | 2010-02-08 | 2015-10-01 | Basf Se | 蝦紅素二琥珀酸二甲酯之製造方法 |
-
2015
- 2015-08-11 BR BR112017004761A patent/BR112017004761A2/pt not_active IP Right Cessation
- 2015-08-11 US US15/509,905 patent/US20170305849A1/en not_active Abandoned
- 2015-08-11 CA CA2958386A patent/CA2958386A1/en not_active Abandoned
- 2015-08-11 AU AU2015314580A patent/AU2015314580A1/en not_active Abandoned
- 2015-08-11 WO PCT/EP2015/068445 patent/WO2016037785A1/de active Application Filing
- 2015-08-11 MX MX2017003237A patent/MX2017003237A/es unknown
- 2015-08-11 JP JP2017513547A patent/JP2017526712A/ja not_active Withdrawn
- 2015-08-11 CN CN201580048767.4A patent/CN106687443A/zh active Pending
- 2015-08-11 EP EP15750406.9A patent/EP3191448A1/de not_active Withdrawn
- 2015-08-11 RU RU2017112051A patent/RU2017112051A/ru not_active Application Discontinuation
- 2015-08-11 KR KR1020177009259A patent/KR20170052630A/ko unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2017526712A (ja) | 2017-09-14 |
| KR20170052630A (ko) | 2017-05-12 |
| RU2017112051A (ru) | 2018-10-11 |
| AU2015314580A1 (en) | 2017-04-06 |
| WO2016037785A1 (de) | 2016-03-17 |
| RU2017112051A3 (pt) | 2019-03-06 |
| EP3191448A1 (de) | 2017-07-19 |
| MX2017003237A (es) | 2017-06-29 |
| CN106687443A (zh) | 2017-05-17 |
| US20170305849A1 (en) | 2017-10-26 |
| CA2958386A1 (en) | 2016-03-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112017004761A2 (pt) | método para preparar um diéster de astaxantina, uso não terapêutico de um diéster, e, diéster | |
| CL2018003681A1 (es) | Derivados de ácido borónico y usos terapéuticos de los mismos | |
| CO2017006214A2 (es) | Derivados de quinazolina utilizados para tratar el vih | |
| CL2020000889A1 (es) | Oligonucleótidos para inducir la expresión paterna de ube3a (divisional solicitud 201801189) | |
| CO2021000456A2 (es) | Compuestos antagonistas de pcsk9 referencia recíproca a solicitudes relacionadas | |
| CL2017000071A1 (es) | Acidos carboxílicos hterocíclicos como activadores de guanilato ciclasa soluble. | |
| BR112018070956A2 (pt) | compostos da fórmula, composições farmacêuticas e métodos para distribuir um ácido nucleico para o fígado de um animal e para preparar um composto da fórmula | |
| BR112018067442A2 (pt) | composto, composição farmacêutica, método de inibir a atividade da amina oxidase, método de tratar uma condição e uso de um composto | |
| DOP2016000248A (es) | Inhibidores de diacilglicerol aciltransferasa 2 | |
| CU20170009A7 (es) | 2-(morfolin-4-il)-1,7-naftiridinas útiles en el tratamiento o la profilaxis de enfermedades hiperproliferativas | |
| BR112016023558A2 (pt) | compostos úteis como imunomoduladores | |
| ECSP17021897A (es) | Compuestos y composiciones como inhibidores de quinasa raf | |
| CL2013000479A1 (es) | Formulacion antimicrobiana que comprende un acido organico c1 a c24 y un aldehido alifatico insaturado; y metodo para el tratamiento del alimento de animales que la contiene | |
| CO7310531A2 (es) | 4-metil-2,3,8,9,9b-pentaaza-ciclopenta [a] naftalenos | |
| CY1124933T1 (el) | Κυτταροτοξικες και αντι-μιτωτικες ενωσεις και μεθοδοι χρησης αυτων | |
| WO2015184311A3 (en) | Method of feeding an animal | |
| NI200900023A (es) | Análogos de 2-fenoxi pirimidinona | |
| MX2018015410A (es) | Esteres de oxaborol y sus usos. | |
| CL2017000312A1 (es) | Elección de microarn como diana para trastornos metabólicos | |
| CL2017000382A1 (es) | Compuestos bicíclicos sustituidos | |
| CL2017000040A1 (es) | Inhibidores de aldosterona sintasa. | |
| BR112016017423A2 (pt) | Monoésteres, sais complexos internos ou sais de monoéster de ácido hexa-hidro-ss e suas aplicações como aditivos para alimentação animal | |
| BR112015029027A2 (pt) | método de obtenção de composições protegidas para alimentação de animais, composições e usos das mesmas | |
| BR112018076734A2 (pt) | compostos heterocíclicos anti-infecciosos e usos dos mesmos | |
| BR112012028919A2 (pt) | sal da rupatadina como um agente anti-histamínico |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B15K | Others concerning applications: alteration of classification |
Ipc: C07C 403/24 (2006.01), A61K 31/23 (2006.01) |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2598 DE 20-10-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |