BR112016025199A8 - métodos de cultura de esporozoítos de plasmodium infecciosos in vitro e para aumentar a produção de oocistos de plasmodium, bem como a referida cultura - Google Patents
métodos de cultura de esporozoítos de plasmodium infecciosos in vitro e para aumentar a produção de oocistos de plasmodium, bem como a referida culturaInfo
- Publication number
- BR112016025199A8 BR112016025199A8 BR112016025199A BR112016025199A BR112016025199A8 BR 112016025199 A8 BR112016025199 A8 BR 112016025199A8 BR 112016025199 A BR112016025199 A BR 112016025199A BR 112016025199 A BR112016025199 A BR 112016025199A BR 112016025199 A8 BR112016025199 A8 BR 112016025199A8
- Authority
- BR
- Brazil
- Prior art keywords
- plasmodium
- vitro
- sporozoites
- methods
- production
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/10—Protozoa; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Farming Of Fish And Shellfish (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
esporozoítos de plasmodium infecciosos cultivados in vitro. a presente invenção refere-se em parte a esporozoítos de plasmodium criados in vitro da faixa de hospedeiros humanos, em que a esporogonia de estágio de gametócitos a estágio de esporozoítos é externa a mosquitos, e métodos de produção dos mesmos. são proporcionados aqui esporozoítos (spz) de plasmodium infecciosos criados in vitro da faixa de hospedeiros humanos, particularmente p. falciparum, p. vivax, p. ovale, p. malariae e p. knowlesi, em que a esporogonia de estágio de gametócitos a estágio de esporozoítos é externa a mosquitos, e métodos de produção dos mesmos.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461987834P | 2014-05-02 | 2014-05-02 | |
| US61/987,834 | 2014-05-02 | ||
| US201462016981P | 2014-06-25 | 2014-06-25 | |
| US62/016,981 | 2014-06-25 | ||
| PCT/US2015/028890 WO2015168620A1 (en) | 2014-05-02 | 2015-05-01 | Infectious plasmodium sporozoites grown in vitro |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR112016025199A2 BR112016025199A2 (pt) | 2017-08-15 |
| BR112016025199A8 true BR112016025199A8 (pt) | 2021-07-13 |
| BR112016025199B1 BR112016025199B1 (pt) | 2023-07-11 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| IL248500A0 (en) | 2016-12-29 |
| JP7021851B2 (ja) | 2022-02-17 |
| US11207395B2 (en) | 2021-12-28 |
| US20160287688A1 (en) | 2016-10-06 |
| US11883475B2 (en) | 2024-01-30 |
| AP2016009590A0 (en) | 2016-11-30 |
| US10441646B2 (en) | 2019-10-15 |
| EP3137106B1 (en) | 2023-07-05 |
| CN106413746A (zh) | 2017-02-15 |
| CA2947595A1 (en) | 2015-11-05 |
| JP2017514490A (ja) | 2017-06-08 |
| US20200113987A1 (en) | 2020-04-16 |
| US9878026B2 (en) | 2018-01-30 |
| KR102467128B1 (ko) | 2022-11-15 |
| JP2020141691A (ja) | 2020-09-10 |
| AU2015252843B2 (en) | 2020-12-24 |
| SG11201608935TA (en) | 2016-11-29 |
| US20240173393A1 (en) | 2024-05-30 |
| ES2954144T3 (es) | 2023-11-20 |
| WO2015168620A1 (en) | 2015-11-05 |
| IL248500B (en) | 2022-07-01 |
| US20180161413A1 (en) | 2018-06-14 |
| EP3137106A4 (en) | 2018-01-17 |
| KR20160147985A (ko) | 2016-12-23 |
| BR112016025199A2 (pt) | 2017-08-15 |
| AU2015252843A1 (en) | 2016-11-17 |
| EP3137106A1 (en) | 2017-03-08 |
| SG10201900876VA (en) | 2019-03-28 |
| US20220257742A1 (en) | 2022-08-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 01/05/2015, OBSERVADAS AS CONDICOES LEGAIS |