SG10201900876VA - Infectious plasmodium sporozoites grown in vitro - Google Patents

Infectious plasmodium sporozoites grown in vitro

Info

Publication number
SG10201900876VA
SG10201900876VA SG10201900876VA SG10201900876VA SG10201900876VA SG 10201900876V A SG10201900876V A SG 10201900876VA SG 10201900876V A SG10201900876V A SG 10201900876VA SG 10201900876V A SG10201900876V A SG 10201900876VA SG 10201900876V A SG10201900876V A SG 10201900876VA
Authority
SG
Singapore
Prior art keywords
vitro
plasmodium sporozoites
grown
stage
infectious plasmodium
Prior art date
Application number
SG10201900876VA
Inventor
Abraham G Eappen
Stephen L Hoffman
Original Assignee
Sanaria Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanaria Inc filed Critical Sanaria Inc
Publication of SG10201900876VA publication Critical patent/SG10201900876VA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/10—Protozoa; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A61P33/12—Schistosomicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

INFECTIOUS PLASMODIUM SPOROZOITES GROWN IN VITRO The application is directed to in vitro-reared Plasmodium sporozoites of human host range wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same. Provided herein are in vitro-reared infectious Plasmodium sporozoites (SPZ) of human host range, particularly P. falciparum, P. vivax, P. ovale, P. malarlae, and P. knowlesi, wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same. No suitable fig.
SG10201900876VA 2014-05-02 2015-05-01 Infectious plasmodium sporozoites grown in vitro SG10201900876VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461987834P 2014-05-02 2014-05-02
US201462016981P 2014-06-25 2014-06-25

Publications (1)

Publication Number Publication Date
SG10201900876VA true SG10201900876VA (en) 2019-03-28

Family

ID=54359397

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201608935TA SG11201608935TA (en) 2014-05-02 2015-05-01 Infectious plasmodium sporozoites grown in vitro
SG10201900876VA SG10201900876VA (en) 2014-05-02 2015-05-01 Infectious plasmodium sporozoites grown in vitro

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201608935TA SG11201608935TA (en) 2014-05-02 2015-05-01 Infectious plasmodium sporozoites grown in vitro

Country Status (12)

Country Link
US (5) US9878026B2 (en)
EP (1) EP3137106B1 (en)
JP (2) JP7021851B2 (en)
KR (1) KR102467128B1 (en)
CN (1) CN106413746A (en)
AP (1) AP2016009590A0 (en)
AU (1) AU2015252843B2 (en)
CA (1) CA2947595A1 (en)
ES (1) ES2954144T3 (en)
IL (1) IL248500B (en)
SG (2) SG11201608935TA (en)
WO (1) WO2015168620A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3137106B1 (en) 2014-05-02 2023-07-05 Sanaria Inc. Infectious plasmodium sporozoites grown in vitro
EP3265815A4 (en) 2015-03-04 2018-08-15 Sanaria Inc. Serum antibody assay for determining protection from malaria, and pre-erythrocytic subunit vaccines
US11332711B1 (en) 2018-04-05 2022-05-17 University Of South Florida Sporozoite cryopreservation compositions and methods

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4824671A (en) * 1986-03-24 1989-04-25 Reuter Laboratories, Inc. In vitro method for producing infective bacterial spores and spore-containing insecticidal compositions
US7015036B2 (en) 2000-09-25 2006-03-21 The United States Of America As Represented By The Secretary Of The Army Human liver cell line
EP2000026B1 (en) 2002-04-05 2014-09-24 Sanaria Inc. Aseptic-anopheles-species insects, aseptic plasmodium-species sporozoites obtained therefrom and a vaccine comprising aseptic plasmodium-species sporozoites
US8802919B2 (en) 2002-04-05 2014-08-12 Sanaria Inc. Apparatuses and methods for the production of haematophagous organisms and parasites suitable for vaccine production
US20050208078A1 (en) 2003-11-20 2005-09-22 Hoffman Stephen L Methods for the prevention of malaria
BR0316423A (en) * 2002-11-20 2005-10-11 Sanaria Inc Method for prevention of malaria
US20050220822A1 (en) * 2003-11-20 2005-10-06 Hoffman Stephen L Methods for the prevention of malaria
EP2128613A1 (en) * 2008-05-28 2009-12-02 Institut Pasteur Method for screening compounds for their ability to increase rigidity of red blood cells infected by a protozoan parasite of the genus plasmodium and application thereof
AU2010204887B2 (en) 2009-01-16 2014-09-25 Sanaria Inc. Purified plasmodium and vaccine compositions
US20120288525A1 (en) 2011-05-11 2012-11-15 Chakravarty Sumana Pharmaceutical compositions comprising attenuated plasmodium sporozoites and glycolipid adjuvants
WO2014116990A1 (en) 2013-01-25 2014-07-31 Sanaria Inc. Genetic attenuation of plasmodium by b9 gene disruption
WO2015031904A2 (en) 2013-08-30 2015-03-05 Sanaria Inc. Serum antibody assay for determining protection from malaria, and pre-erythrocytic subunit vaccines
EP3137106B1 (en) 2014-05-02 2023-07-05 Sanaria Inc. Infectious plasmodium sporozoites grown in vitro
EP3265815A4 (en) 2015-03-04 2018-08-15 Sanaria Inc. Serum antibody assay for determining protection from malaria, and pre-erythrocytic subunit vaccines

Also Published As

Publication number Publication date
IL248500A0 (en) 2016-12-29
JP7021851B2 (en) 2022-02-17
US11207395B2 (en) 2021-12-28
US20160287688A1 (en) 2016-10-06
US11883475B2 (en) 2024-01-30
AP2016009590A0 (en) 2016-11-30
US10441646B2 (en) 2019-10-15
BR112016025199A8 (en) 2021-07-13
EP3137106B1 (en) 2023-07-05
CN106413746A (en) 2017-02-15
CA2947595A1 (en) 2015-11-05
JP2017514490A (en) 2017-06-08
US20200113987A1 (en) 2020-04-16
US9878026B2 (en) 2018-01-30
KR102467128B1 (en) 2022-11-15
JP2020141691A (en) 2020-09-10
AU2015252843B2 (en) 2020-12-24
SG11201608935TA (en) 2016-11-29
US20240173393A1 (en) 2024-05-30
ES2954144T3 (en) 2023-11-20
WO2015168620A1 (en) 2015-11-05
IL248500B (en) 2022-07-01
US20180161413A1 (en) 2018-06-14
EP3137106A4 (en) 2018-01-17
KR20160147985A (en) 2016-12-23
BR112016025199A2 (en) 2017-08-15
AU2015252843A1 (en) 2016-11-17
EP3137106A1 (en) 2017-03-08
US20220257742A1 (en) 2022-08-18

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