BR112016025199A2 - esporozoítos de plasmodium infecci¬osos cultivados in vitro - Google Patents

esporozoítos de plasmodium infecci¬osos cultivados in vitro

Info

Publication number
BR112016025199A2
BR112016025199A2 BR112016025199A BR112016025199A BR112016025199A2 BR 112016025199 A2 BR112016025199 A2 BR 112016025199A2 BR 112016025199 A BR112016025199 A BR 112016025199A BR 112016025199 A BR112016025199 A BR 112016025199A BR 112016025199 A2 BR112016025199 A2 BR 112016025199A2
Authority
BR
Brazil
Prior art keywords
plasmodium sporozoites
stage
vitro
vitro cultivated
infectious plasmodium
Prior art date
Application number
BR112016025199A
Other languages
English (en)
Other versions
BR112016025199A8 (pt
BR112016025199B1 (pt
Inventor
G Eappen Abraham
L Hoffman Stephen
Original Assignee
Sanaria Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanaria Inc filed Critical Sanaria Inc
Publication of BR112016025199A2 publication Critical patent/BR112016025199A2/pt
Publication of BR112016025199A8 publication Critical patent/BR112016025199A8/pt
Publication of BR112016025199B1 publication Critical patent/BR112016025199B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • A61K39/015Hemosporidia antigens, e.g. Plasmodium antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • A61P33/12Schistosomicides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/10Protozoa; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

a presente invenção refere-se em parte a esporozoítos de plasmodium criados in vitro da faixa de hospedeiros humanos, em que a esporogonia de estágio de gametócitos a estágio de esporozoítos é externa a mosquitos, e métodos de produção dos mesmos. são proporcionados aqui esporozoítos (spz) de plasmodium infecciosos criados in vitro da faixa de hospedeiros humanos, particularmente p. falci-parum, p. vivax, p. ovale, p. malariae e p. knowlesi, em que a esporogonia de estágio de gametócitos a estágio de esporozoítos é externa a mosquitos, e métodos de produção dos mesmos.
BR112016025199-7A 2014-05-02 2015-05-01 Métodos de cultura de esporozoítos de plasmodium falciparum infecciosos in vitro e para aumentar a produção de oocistos de plasmodium falciparum, bem como a referida cultura BR112016025199B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461987834P 2014-05-02 2014-05-02
US61/987,834 2014-05-02
US201462016981P 2014-06-25 2014-06-25
US62/016,981 2014-06-25
PCT/US2015/028890 WO2015168620A1 (en) 2014-05-02 2015-05-01 Infectious plasmodium sporozoites grown in vitro

Publications (3)

Publication Number Publication Date
BR112016025199A2 true BR112016025199A2 (pt) 2017-08-15
BR112016025199A8 BR112016025199A8 (pt) 2021-07-13
BR112016025199B1 BR112016025199B1 (pt) 2023-07-11

Family

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Also Published As

Publication number Publication date
US20180161413A1 (en) 2018-06-14
AU2015252843B2 (en) 2020-12-24
US20240173393A1 (en) 2024-05-30
US11207395B2 (en) 2021-12-28
SG10201900876VA (en) 2019-03-28
BR112016025199A8 (pt) 2021-07-13
US9878026B2 (en) 2018-01-30
US11883475B2 (en) 2024-01-30
US10441646B2 (en) 2019-10-15
EP3137106A1 (en) 2017-03-08
JP2017514490A (ja) 2017-06-08
US20220257742A1 (en) 2022-08-18
WO2015168620A1 (en) 2015-11-05
EP3137106B1 (en) 2023-07-05
KR102467128B1 (ko) 2022-11-15
SG11201608935TA (en) 2016-11-29
AU2015252843A1 (en) 2016-11-17
US20160287688A1 (en) 2016-10-06
JP7021851B2 (ja) 2022-02-17
AP2016009590A0 (en) 2016-11-30
JP2020141691A (ja) 2020-09-10
CA2947595A1 (en) 2015-11-05
KR20160147985A (ko) 2016-12-23
IL248500A0 (en) 2016-12-29
CN106413746A (zh) 2017-02-15
IL248500B (en) 2022-07-01
US20200113987A1 (en) 2020-04-16
EP3137106A4 (en) 2018-01-17
ES2954144T3 (es) 2023-11-20

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 01/05/2015, OBSERVADAS AS CONDICOES LEGAIS