BR112012016048A2 - "exossomas derivados de reticulócitos infectados com plasmodium sp., método para obter os mesmos e usos dos mesmos". - Google Patents

"exossomas derivados de reticulócitos infectados com plasmodium sp., método para obter os mesmos e usos dos mesmos".

Info

Publication number
BR112012016048A2
BR112012016048A2 BR112012016048A BR112012016048A BR112012016048A2 BR 112012016048 A2 BR112012016048 A2 BR 112012016048A2 BR 112012016048 A BR112012016048 A BR 112012016048A BR 112012016048 A BR112012016048 A BR 112012016048A BR 112012016048 A2 BR112012016048 A2 BR 112012016048A2
Authority
BR
Brazil
Prior art keywords
plasmodium
infected
obtaining
exosomes
reticulocyte
Prior art date
Application number
BR112012016048A
Other languages
English (en)
Inventor
Antonio Del Portillo Obando Hernando
Original Assignee
Centre De Recerca En Salut Int De Barcelona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre De Recerca En Salut Int De Barcelona filed Critical Centre De Recerca En Salut Int De Barcelona
Publication of BR112012016048A2 publication Critical patent/BR112012016048A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)

Abstract

patente de invenção para : " exossomas derivados de reticulócitos infectados com plasmodium sp., método para obter os mesmos e usos dos mesmos". a presente invenção pertence ao campo de vacinas para a prevenção e profilaxia contra malária, mais especificamente se refere a exossomas isolados de reticulócitos infectados com plasmodium sp., a métodos para obter os mesmos e ao uso dos mesmos para a prevenção e profilaxia contra malária bem como a seu uso para a descoberta e identificação de novos antígenos de plasmodium. a invenção também se refere a exossomas artificiais que compreendem antígeno de plasmodium sp.s. finalmente, a invenção se refere a antígenos específicos descobertos por meio dos exossomas obtidos de reticulócitos infectados com plasmodium sp.
BR112012016048A 2009-12-28 2010-12-28 "exossomas derivados de reticulócitos infectados com plasmodium sp., método para obter os mesmos e usos dos mesmos". BR112012016048A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200931275A ES2362589B1 (es) 2009-12-28 2009-12-28 Exosomas derivados de reticulocitos infectados con plasmodium sp., método para su obtención y su uso.
PCT/EP2010/070800 WO2011080271A2 (en) 2009-12-28 2010-12-28 Exosomes derived from reticulocytes infected with plasmodium sp., method for obtaining them and uses thereof

Publications (1)

Publication Number Publication Date
BR112012016048A2 true BR112012016048A2 (pt) 2019-09-24

Family

ID=44121766

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012016048A BR112012016048A2 (pt) 2009-12-28 2010-12-28 "exossomas derivados de reticulócitos infectados com plasmodium sp., método para obter os mesmos e usos dos mesmos".

Country Status (8)

Country Link
US (1) US8790661B2 (pt)
EP (1) EP2519254B1 (pt)
JP (1) JP2013515495A (pt)
CN (1) CN102844046A (pt)
AU (1) AU2010338274A1 (pt)
BR (1) BR112012016048A2 (pt)
ES (1) ES2362589B1 (pt)
WO (1) WO2011080271A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014142235A1 (ja) 2013-03-13 2014-09-18 Li Zhong 微小胞及びその製造方法
US10987432B2 (en) 2013-09-05 2021-04-27 The University Of Hong Kong Therapeutic delivery and expression system, methods and uses thereof
RU2556825C1 (ru) * 2014-09-15 2015-07-20 Федеральное государственное бюджетное учреждение науки Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук (ИХБФМ СО РАН) Способ получения экзосом из крови
JP2017101012A (ja) * 2015-11-30 2017-06-08 義之 小山 免疫治療製剤
CN108066361A (zh) * 2017-01-23 2018-05-25 广州中科蓝华生物科技有限公司 一种外泌体，其制备方法及其在制备抗肿瘤的药物或者制剂中的用途
CN107176991B (zh) * 2017-05-23 2020-05-12 中国医科大学 一种伯氏疟原虫配子体重组蛋白rPbG37在疟疾传播阻断中的应用
CN107056920B (zh) * 2017-05-23 2020-05-12 中国医科大学 一种伯氏疟原虫配子体重组蛋白rPgmp22在疟疾传播阻断中的应用
JP2022513311A (ja) * 2018-09-21 2022-02-07 シティー・ユニバーシティー・オブ・ホンコン カーゴ積載細胞外小胞
CN113144222B (zh) * 2021-04-14 2023-05-23 台州学院 外泌体用于防止脑型疟疾发生的实验方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE319477T1 (de) 1995-08-03 2006-03-15 Univ Leiden Antigen presentierende bläschen, die von zellen ableiten
FR2766205B1 (fr) 1997-07-16 2002-08-30 Inst Nat Sante Rech Med Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede
FR2785543B1 (fr) 1998-11-05 2003-02-28 Inst Nat Sante Rech Med Exosomes modifies et utilisations
KR100519384B1 (ko) 2002-08-13 2005-10-06 (주)누백스 유전자 이입을 이용한 엑소좀의 제조방법 및 상기 엑소좀의 용도
GB0401238D0 (en) * 2004-01-21 2004-02-25 Molecularnature Ltd Immunomodulatory alkaloids
CA2676143A1 (en) * 2007-01-26 2008-07-31 University Of Louisville Research Foundation, Inc. Modification of exosomal components for use as a vaccine

Also Published As

Publication number Publication date
AU2010338274A1 (en) 2012-07-19
ES2362589B1 (es) 2012-05-16
EP2519254B1 (en) 2017-05-03
ES2362589A1 (es) 2011-07-08
WO2011080271A2 (en) 2011-07-07
JP2013515495A (ja) 2013-05-09
US20120321676A1 (en) 2012-12-20
WO2011080271A3 (en) 2012-01-05
EP2519254A2 (en) 2012-11-07
CN102844046A (zh) 2012-12-26
US8790661B2 (en) 2014-07-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.