BR112016021171B8 - processo para fabricação de composto oticamente ativo - Google Patents

processo para fabricação de composto oticamente ativo

Info

Publication number
BR112016021171B8
BR112016021171B8 BR112016021171A BR112016021171A BR112016021171B8 BR 112016021171 B8 BR112016021171 B8 BR 112016021171B8 BR 112016021171 A BR112016021171 A BR 112016021171A BR 112016021171 A BR112016021171 A BR 112016021171A BR 112016021171 B8 BR112016021171 B8 BR 112016021171B8
Authority
BR
Brazil
Prior art keywords
group
optically active
active compound
formula
manufacturing
Prior art date
Application number
BR112016021171A
Other languages
English (en)
Other versions
BR112016021171B1 (pt
Inventor
Ujita Satoru
Takahashi Tomoaki
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of BR112016021171B1 publication Critical patent/BR112016021171B1/pt
Publication of BR112016021171B8 publication Critical patent/BR112016021171B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/08—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms with acylated ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)

Abstract

processo para fabricação de composto oticamente ativo. a presente invenção refere-se a um processo para fabricação de um composto oticamente ativo de fórmula (2), que contém colocação de hidrogênio em contato com um composto de fórmula (1) na presença de um catalisador metal de transição tendo um ligante oticamente ativo. (1) (2) na fórmula, r1 representa um átomo de hidrogênio ou um grupo acetila, r2, r3, r4, e r5, cada um independentemente, representam um átomo de hidrogênio, um átomo de halogênio, um grupo alquila, um grupo alcóxi, um grupo hidróxi, um grupo nitro, um grupo amino, ou um grupo acila, r6 representa um grupo alquila, r7 e r8, cada um independentemente, representam um átomo de hidrogênio ou um grupo alquila, e um átomo de carbono marcado com um asterisco (*) representa um átomo de carbono assimétrico.
BR112016021171A 2014-03-18 2015-03-06 processo para fabricação de composto oticamente ativo BR112016021171B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2014-054457 2014-03-18
JP2014054457 2014-03-18
PCT/JP2015/057395 WO2015141564A1 (ja) 2014-03-18 2015-03-06 光学活性な化合物の製造方法

Publications (2)

Publication Number Publication Date
BR112016021171B1 BR112016021171B1 (pt) 2021-01-26
BR112016021171B8 true BR112016021171B8 (pt) 2021-02-09

Family

ID=54144534

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016021171A BR112016021171B8 (pt) 2014-03-18 2015-03-06 processo para fabricação de composto oticamente ativo

Country Status (6)

Country Link
US (1) US9796678B2 (pt)
JP (1) JP6624050B2 (pt)
CN (1) CN106103413A (pt)
BR (1) BR112016021171B8 (pt)
DE (1) DE112015001290T5 (pt)
WO (1) WO2015141564A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3774735B1 (en) * 2018-03-26 2023-09-13 Bayer Aktiengesellschaft Enantioselective hydrogenation of 4-substituted 1,2-dihydroquinolines in presence of a chiral iridium catalyst
JP2022549636A (ja) 2019-09-25 2022-11-28 バイエル・アクチエンゲゼルシヤフト ４－置換１，２－ジヒドロキノリン類のエナンチオ選択的水素化のための新規イリジウム触媒の使用を含む方法
BR112022005473A2 (pt) 2019-09-25 2022-06-14 Bayer Ag Hidrogenação enantiosseletiva melhorada de 1,2- dihidroquinolinas 4-substituídas na presença de um catalisador de irídio quiral e um aditivo
BR112022026601A2 (pt) 2020-07-17 2023-01-24 Sumitomo Chemical Co Processos para preparação de um composto opticamente ativo, incluindo 1,1,3-trimetil-4-aminoindano, e complexos de cobalto assimétrico, de hidreto e de alquila
CN114773263B (zh) * 2022-05-16 2023-09-05 江苏百康德医药科技有限公司 (r)-2,2,4-三甲基-1,2,3,4-四氢喹啉的制备方法
WO2024041976A1 (en) 2022-08-23 2024-02-29 Bayer Aktiengesellschaft Process for distillative recovery of 1,1,1,3,3,3-hexafluoro-2-propanol (hfip) from mixtures with 4- substituted 1,2,3,4-tetrahydroquinolines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087561A (en) * 1975-12-22 1978-05-02 Canada Packers Limited Control of nitrosamine formation in nitride cured meat with 1,2,3,4-tetrahydro-quinoline compounds
US5521317A (en) * 1993-10-22 1996-05-28 American Cyanamid Co. Processes for the preparation of pesticides and intermediates
ES2240297T3 (es) * 2000-09-21 2005-10-16 Solvias Ag Fosfinito-oxazolinas y complejos metalicos.

Also Published As

Publication number Publication date
WO2015141564A1 (ja) 2015-09-24
DE112015001290T5 (de) 2016-12-29
CN106103413A (zh) 2016-11-09
JP6624050B2 (ja) 2019-12-25
BR112016021171B1 (pt) 2021-01-26
US9796678B2 (en) 2017-10-24
US20170022162A1 (en) 2017-01-26
JPWO2015141564A1 (ja) 2017-04-06

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Legal Events

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B06U Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure
B09A Decision: intention to grant
B09W Decision of grant: rectification

Free format text: REFERENCIA: RPI 2605 DE 08.12.2020 - CODIGO 9.1

B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/03/2015, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant

Free format text: REFERENTE AO DESPACHO 16.1 PUBLICADO NA RPI 2612 DE 26.01.2021, QUANTO AO QUADRO REIVINDICATORIO