BR112016006210A2 - terapia e vacina contra gripe - Google Patents

terapia e vacina contra gripe

Info

Publication number
BR112016006210A2
BR112016006210A2 BR112016006210A BR112016006210A BR112016006210A2 BR 112016006210 A2 BR112016006210 A2 BR 112016006210A2 BR 112016006210 A BR112016006210 A BR 112016006210A BR 112016006210 A BR112016006210 A BR 112016006210A BR 112016006210 A2 BR112016006210 A2 BR 112016006210A2
Authority
BR
Brazil
Prior art keywords
individuals
vaccine
influenza virus
therapy
susceptible
Prior art date
Application number
BR112016006210A
Other languages
English (en)
Inventor
Bucher Doris
Alfenito Mark
Baer Mark
Original Assignee
Engen Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Engen Bio Inc filed Critical Engen Bio Inc
Publication of BR112016006210A2 publication Critical patent/BR112016006210A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

resumo terapia e vacina contra gripe a presente invenção é dirigida geralmente a polipeptídeos m1 que podem ser usados como vacinas e/ou antígenos para a produção de anticorpos de polipeptídeo anti-mi para o tratamento profilático de indivíduos que são suscetíveis à infeção pelo vírus da influenza. os anticorpos de polipeptídeo anti-m1 da invenção são úteis para o tratamento de indivíduos infectados com o vírus da influenza, ou úteis para tratamento profilático de indivíduos que são suscetíveis à infeção pelo vírus da influenza, ou em indivíduos imunossuprimidos que não podem gerar uma resposta de anticorpo eficaz.
BR112016006210A 2013-09-23 2014-09-21 terapia e vacina contra gripe BR112016006210A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361881325P 2013-09-23 2013-09-23
PCT/US2014/056703 WO2015042498A1 (en) 2013-09-23 2014-09-21 Influenza vaccine and therapy

Publications (1)

Publication Number Publication Date
BR112016006210A2 true BR112016006210A2 (pt) 2017-09-26

Family

ID=52689487

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016006210A BR112016006210A2 (pt) 2013-09-23 2014-09-21 terapia e vacina contra gripe

Country Status (11)

Country Link
US (1) US9999662B2 (pt)
EP (1) EP3049112B1 (pt)
JP (1) JP6877143B2 (pt)
KR (1) KR20160055825A (pt)
CN (1) CN104436157A (pt)
AU (1) AU2014321314A1 (pt)
BR (1) BR112016006210A2 (pt)
CA (1) CA2923226A1 (pt)
ES (1) ES2833156T3 (pt)
IL (1) IL244354B (pt)
WO (1) WO2015042498A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6262969B2 (ja) * 2013-09-10 2018-01-17 デンカ生研株式会社 Ａ型インフルエンザウイルスの測定方法
CN104436157A (zh) 2013-09-23 2015-03-25 恩金生物有限公司 流感疫苗和治疗
US10080792B2 (en) 2013-09-23 2018-09-25 Engen Bio, Inc. Influenza vaccine and therapy
WO2016168835A1 (en) * 2015-04-17 2016-10-20 South Dakota Board Of Regents Compositions and methods for vaccination against influenza a virus
WO2017049395A1 (en) * 2015-09-23 2017-03-30 Dectronique (1984) Inc. Electronic vision system and use thereof
JP6782218B2 (ja) * 2017-11-17 2020-11-11 株式会社東芝 検出装置および検出方法
CN110680912B (zh) * 2019-09-26 2021-08-17 中国农业大学 H3n2和h3n8亚型犬流感二价灭活苗及其制备方法与应用

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Also Published As

Publication number Publication date
CN104436157A (zh) 2015-03-25
EP3049112A1 (en) 2016-08-03
JP2016531934A (ja) 2016-10-13
IL244354B (en) 2021-12-01
AU2014321314A1 (en) 2016-03-17
CA2923226A1 (en) 2015-03-26
IL244354A0 (en) 2016-04-21
KR20160055825A (ko) 2016-05-18
US20150086560A1 (en) 2015-03-26
WO2015042498A1 (en) 2015-03-26
EP3049112A4 (en) 2017-07-12
EP3049112B1 (en) 2020-09-09
ES2833156T3 (es) 2021-06-14
JP6877143B2 (ja) 2021-05-26
US9999662B2 (en) 2018-06-19

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B350 Update of information on the portal [chapter 15.35 patent gazette]