BR112016001400B1 - Uso de ácidos fenoxialquilcarboxílicos para preparação de medicamentos para a redução de níveis sanguíneos de triglicerídeos, colesterol total e lipoproteínas de baixa densidade - Google Patents
Uso de ácidos fenoxialquilcarboxílicos para preparação de medicamentos para a redução de níveis sanguíneos de triglicerídeos, colesterol total e lipoproteínas de baixa densidade Download PDFInfo
- Publication number
- BR112016001400B1 BR112016001400B1 BR112016001400-6A BR112016001400A BR112016001400B1 BR 112016001400 B1 BR112016001400 B1 BR 112016001400B1 BR 112016001400 A BR112016001400 A BR 112016001400A BR 112016001400 B1 BR112016001400 B1 BR 112016001400B1
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- BR
- Brazil
- Prior art keywords
- compound
- formula
- fact
- day
- metabolite
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361858450P | 2013-07-25 | 2013-07-25 | |
| US61/858,450 | 2013-07-25 | ||
| PCT/US2014/047797 WO2015013395A1 (en) | 2013-07-25 | 2014-07-23 | Methods for reducing triglyceride, total cholesterol and low density lipoprotein blood levels |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR112016001400A2 BR112016001400A2 (pt) | 2017-07-25 |
| BR112016001400A8 BR112016001400A8 (pt) | 2020-01-14 |
| BR112016001400B1 true BR112016001400B1 (pt) | 2023-02-28 |
Family
ID=52391020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112016001400-6A BR112016001400B1 (pt) | 2013-07-25 | 2014-07-23 | Uso de ácidos fenoxialquilcarboxílicos para preparação de medicamentos para a redução de níveis sanguíneos de triglicerídeos, colesterol total e lipoproteínas de baixa densidade |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20150031769A1 (enExample) |
| EP (1) | EP3024454B1 (enExample) |
| JP (1) | JP6363192B2 (enExample) |
| KR (1) | KR102352728B1 (enExample) |
| CN (1) | CN105407884B (enExample) |
| BR (1) | BR112016001400B1 (enExample) |
| CA (1) | CA2917780C (enExample) |
| ES (1) | ES2843511T3 (enExample) |
| WO (1) | WO2015013395A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3217719A1 (en) * | 2021-05-28 | 2022-12-01 | Kazuko Matsuda | Phenoxyalkylcarboxylic acid derivatives and their use in lowering triglyceride levels |
| EP4628075A1 (en) | 2022-11-30 | 2025-10-08 | Kao Corporation | Agent for preventing or ameliorating pruritus |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2585246A1 (fr) | 1985-07-26 | 1987-01-30 | Cortial | Procede d'obtention de formes pharmaceutiques solides a liberation prolongee |
| US4788055A (en) | 1985-12-09 | 1988-11-29 | Ciba-Geigy Corporation | Resinate sustained release dextromethorphan composition |
| GB8613689D0 (en) | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| GB8613688D0 (en) | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| US4816264A (en) | 1986-06-06 | 1989-03-28 | Warner-Lambert Company | Sustained release formulations |
| US4985585A (en) | 1988-03-07 | 1991-01-15 | Kyorin Pharmaceutical Co., Ltd. | Phenoxyalkylcarboxylic acid derivatives and process for their preparations |
| US4996047A (en) | 1988-11-02 | 1991-02-26 | Richardson-Vicks, Inc. | Sustained release drug-resin complexes |
| CA2002492A1 (en) | 1988-11-11 | 1990-05-11 | Sandra T. A. Malkowska | Pharmaceutical ion exchange resin composition |
| US5133974A (en) | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
| US5290812A (en) | 1991-01-18 | 1994-03-01 | Kyorin Pharmaceutical Co., Ltd. | Phenoxyalkylcarboxylic acid derivatives and process of preparing the same |
| US7060854B2 (en) | 2003-06-24 | 2006-06-13 | Medicinova, Inc. | Process for making polymorphic form A of 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid |
| US7064146B2 (en) | 2003-06-24 | 2006-06-20 | Medicinova, Inc. | Pharmaceutical compositions of isolated orthorhombic crystalline 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid and methods of use |
| JP2007534771A (ja) * | 2004-04-27 | 2007-11-29 | メディシノバ，インコーポレーテッド | 炎症性疾患の治療におけるフェノキシアルキルカルボン酸誘導体 |
| CA2571683A1 (en) * | 2004-06-30 | 2006-01-12 | Combinatorx, Incorporated | Methods and reagents for the treatment of metabolic disorders |
| WO2006132091A1 (ja) * | 2005-06-08 | 2006-12-14 | Kowa Company, Ltd. | 新規なトリグリセリド低下剤 |
| WO2009002746A1 (en) * | 2007-06-22 | 2008-12-31 | Decode Genetics Ehf. | Dosing schedules of leukotriene synthesis inhibitors for human therapy |
-
2014
- 2014-07-23 EP EP14829314.5A patent/EP3024454B1/en active Active
- 2014-07-23 BR BR112016001400-6A patent/BR112016001400B1/pt active IP Right Grant
- 2014-07-23 KR KR1020167002772A patent/KR102352728B1/ko active Active
- 2014-07-23 JP JP2016529856A patent/JP6363192B2/ja active Active
- 2014-07-23 WO PCT/US2014/047797 patent/WO2015013395A1/en not_active Ceased
- 2014-07-23 ES ES14829314T patent/ES2843511T3/es active Active
- 2014-07-23 US US14/339,331 patent/US20150031769A1/en not_active Abandoned
- 2014-07-23 CN CN201480041441.4A patent/CN105407884B/zh active Active
- 2014-07-23 CA CA2917780A patent/CA2917780C/en active Active
- 2014-11-13 US US14/540,766 patent/US9358217B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3024454A1 (en) | 2016-06-01 |
| US20150080471A1 (en) | 2015-03-19 |
| US9358217B2 (en) | 2016-06-07 |
| CN105407884A (zh) | 2016-03-16 |
| ES2843511T3 (es) | 2021-07-19 |
| EP3024454B1 (en) | 2020-10-21 |
| US20150031769A1 (en) | 2015-01-29 |
| WO2015013395A1 (en) | 2015-01-29 |
| BR112016001400A8 (pt) | 2020-01-14 |
| CA2917780A1 (en) | 2015-01-29 |
| BR112016001400A2 (pt) | 2017-07-25 |
| JP2016525546A (ja) | 2016-08-25 |
| CN105407884B (zh) | 2019-04-30 |
| KR102352728B1 (ko) | 2022-01-18 |
| CA2917780C (en) | 2023-01-24 |
| KR20160034324A (ko) | 2016-03-29 |
| EP3024454A4 (en) | 2017-03-15 |
| JP6363192B2 (ja) | 2018-07-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B25G | Requested change of headquarter approved |
Owner name: MEDICINOVA, INC. (US) |
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| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 23/07/2014, OBSERVADAS AS CONDICOES LEGAIS |