CA2917780C - Methods for reducing triglyceride, total cholesterol and low density lipoprotein blood levels - Google Patents
Methods for reducing triglyceride, total cholesterol and low density lipoprotein blood levels Download PDFInfo
- Publication number
- CA2917780C CA2917780C CA2917780A CA2917780A CA2917780C CA 2917780 C CA2917780 C CA 2917780C CA 2917780 A CA2917780 A CA 2917780A CA 2917780 A CA2917780 A CA 2917780A CA 2917780 C CA2917780 C CA 2917780C
- Authority
- CA
- Canada
- Prior art keywords
- compound
- formula
- formulated
- day
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361858450P | 2013-07-25 | 2013-07-25 | |
| US61/858,450 | 2013-07-25 | ||
| PCT/US2014/047797 WO2015013395A1 (en) | 2013-07-25 | 2014-07-23 | Methods for reducing triglyceride, total cholesterol and low density lipoprotein blood levels |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2917780A1 CA2917780A1 (en) | 2015-01-29 |
| CA2917780C true CA2917780C (en) | 2023-01-24 |
Family
ID=52391020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2917780A Active CA2917780C (en) | 2013-07-25 | 2014-07-23 | Methods for reducing triglyceride, total cholesterol and low density lipoprotein blood levels |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20150031769A1 (enExample) |
| EP (1) | EP3024454B1 (enExample) |
| JP (1) | JP6363192B2 (enExample) |
| KR (1) | KR102352728B1 (enExample) |
| CN (1) | CN105407884B (enExample) |
| BR (1) | BR112016001400B1 (enExample) |
| CA (1) | CA2917780C (enExample) |
| ES (1) | ES2843511T3 (enExample) |
| WO (1) | WO2015013395A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2024522030A (ja) | 2021-05-28 | 2024-06-10 | メディシノバ・インコーポレイテッド | フェノキシアルキルカルボン酸誘導体、およびトリグリセリドレベルを低下させることにおけるその使用 |
| WO2024117173A1 (ja) | 2022-11-30 | 2024-06-06 | 花王株式会社 | 痒みの予防又は改善剤 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2585246A1 (fr) | 1985-07-26 | 1987-01-30 | Cortial | Procede d'obtention de formes pharmaceutiques solides a liberation prolongee |
| US4788055A (en) | 1985-12-09 | 1988-11-29 | Ciba-Geigy Corporation | Resinate sustained release dextromethorphan composition |
| GB8613688D0 (en) | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| GB8613689D0 (en) | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| US4816264A (en) | 1986-06-06 | 1989-03-28 | Warner-Lambert Company | Sustained release formulations |
| US4985585A (en) | 1988-03-07 | 1991-01-15 | Kyorin Pharmaceutical Co., Ltd. | Phenoxyalkylcarboxylic acid derivatives and process for their preparations |
| US4996047A (en) | 1988-11-02 | 1991-02-26 | Richardson-Vicks, Inc. | Sustained release drug-resin complexes |
| CA2002492A1 (en) | 1988-11-11 | 1990-05-11 | Sandra T. A. Malkowska | Pharmaceutical ion exchange resin composition |
| US5133974A (en) | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
| US5290812A (en) | 1991-01-18 | 1994-03-01 | Kyorin Pharmaceutical Co., Ltd. | Phenoxyalkylcarboxylic acid derivatives and process of preparing the same |
| US7060854B2 (en) | 2003-06-24 | 2006-06-13 | Medicinova, Inc. | Process for making polymorphic form A of 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid |
| US7064146B2 (en) | 2003-06-24 | 2006-06-20 | Medicinova, Inc. | Pharmaceutical compositions of isolated orthorhombic crystalline 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid and methods of use |
| KR20070058381A (ko) * | 2004-04-27 | 2007-06-08 | 메디시노바, 인크. | 염증성 질환 치료용 페녹시알킬카르복실 산 유도체 |
| AU2005259864A1 (en) * | 2004-06-30 | 2006-01-12 | Combinatorx, Incorporated | Methods and reagents for the treatment of metabolic disorders |
| CN101193656B (zh) * | 2005-06-08 | 2011-03-02 | 兴和株式会社 | 甘油三酸酯降低剂 |
| WO2009002746A1 (en) * | 2007-06-22 | 2008-12-31 | Decode Genetics Ehf. | Dosing schedules of leukotriene synthesis inhibitors for human therapy |
-
2014
- 2014-07-23 CA CA2917780A patent/CA2917780C/en active Active
- 2014-07-23 EP EP14829314.5A patent/EP3024454B1/en active Active
- 2014-07-23 CN CN201480041441.4A patent/CN105407884B/zh active Active
- 2014-07-23 WO PCT/US2014/047797 patent/WO2015013395A1/en not_active Ceased
- 2014-07-23 JP JP2016529856A patent/JP6363192B2/ja active Active
- 2014-07-23 KR KR1020167002772A patent/KR102352728B1/ko active Active
- 2014-07-23 ES ES14829314T patent/ES2843511T3/es active Active
- 2014-07-23 BR BR112016001400-6A patent/BR112016001400B1/pt active IP Right Grant
- 2014-07-23 US US14/339,331 patent/US20150031769A1/en not_active Abandoned
- 2014-11-13 US US14/540,766 patent/US9358217B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2843511T3 (es) | 2021-07-19 |
| EP3024454A1 (en) | 2016-06-01 |
| BR112016001400A8 (pt) | 2020-01-14 |
| EP3024454A4 (en) | 2017-03-15 |
| WO2015013395A1 (en) | 2015-01-29 |
| KR102352728B1 (ko) | 2022-01-18 |
| US20150080471A1 (en) | 2015-03-19 |
| US20150031769A1 (en) | 2015-01-29 |
| CN105407884A (zh) | 2016-03-16 |
| EP3024454B1 (en) | 2020-10-21 |
| CA2917780A1 (en) | 2015-01-29 |
| BR112016001400A2 (pt) | 2017-07-25 |
| CN105407884B (zh) | 2019-04-30 |
| KR20160034324A (ko) | 2016-03-29 |
| JP6363192B2 (ja) | 2018-07-25 |
| BR112016001400B1 (pt) | 2023-02-28 |
| US9358217B2 (en) | 2016-06-07 |
| JP2016525546A (ja) | 2016-08-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20190716 |
|
| EEER | Examination request |
Effective date: 20190716 |
|
| EEER | Examination request |
Effective date: 20190716 |
|
| EEER | Examination request |
Effective date: 20190716 |
|
| EEER | Examination request |
Effective date: 20190716 |