ES2843511T3 - Métodos para reducir las concentraciones en sangre de triglicéridos, colesterol total y lipoproteínas de baja densidad - Google Patents

Métodos para reducir las concentraciones en sangre de triglicéridos, colesterol total y lipoproteínas de baja densidad Download PDF

Info

Publication number
ES2843511T3
ES2843511T3 ES14829314T ES14829314T ES2843511T3 ES 2843511 T3 ES2843511 T3 ES 2843511T3 ES 14829314 T ES14829314 T ES 14829314T ES 14829314 T ES14829314 T ES 14829314T ES 2843511 T3 ES2843511 T3 ES 2843511T3
Authority
ES
Spain
Prior art keywords
compound
metabolite
formula
ester
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES14829314T
Other languages
English (en)
Spanish (es)
Inventor
Kazuko Matsuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicinova Inc
Original Assignee
Medicinova Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicinova Inc filed Critical Medicinova Inc
Application granted granted Critical
Publication of ES2843511T3 publication Critical patent/ES2843511T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
ES14829314T 2013-07-25 2014-07-23 Métodos para reducir las concentraciones en sangre de triglicéridos, colesterol total y lipoproteínas de baja densidad Active ES2843511T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361858450P 2013-07-25 2013-07-25
PCT/US2014/047797 WO2015013395A1 (en) 2013-07-25 2014-07-23 Methods for reducing triglyceride, total cholesterol and low density lipoprotein blood levels

Publications (1)

Publication Number Publication Date
ES2843511T3 true ES2843511T3 (es) 2021-07-19

Family

ID=52391020

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14829314T Active ES2843511T3 (es) 2013-07-25 2014-07-23 Métodos para reducir las concentraciones en sangre de triglicéridos, colesterol total y lipoproteínas de baja densidad

Country Status (9)

Country Link
US (2) US20150031769A1 (enExample)
EP (1) EP3024454B1 (enExample)
JP (1) JP6363192B2 (enExample)
KR (1) KR102352728B1 (enExample)
CN (1) CN105407884B (enExample)
BR (1) BR112016001400B1 (enExample)
CA (1) CA2917780C (enExample)
ES (1) ES2843511T3 (enExample)
WO (1) WO2015013395A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024522030A (ja) 2021-05-28 2024-06-10 メディシノバ・インコーポレイテッド フェノキシアルキルカルボン酸誘導体、およびトリグリセリドレベルを低下させることにおけるその使用
WO2024117173A1 (ja) 2022-11-30 2024-06-06 花王株式会社 痒みの予防又は改善剤

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2585246A1 (fr) 1985-07-26 1987-01-30 Cortial Procede d'obtention de formes pharmaceutiques solides a liberation prolongee
US4788055A (en) 1985-12-09 1988-11-29 Ciba-Geigy Corporation Resinate sustained release dextromethorphan composition
GB8613688D0 (en) 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
GB8613689D0 (en) 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
US4816264A (en) 1986-06-06 1989-03-28 Warner-Lambert Company Sustained release formulations
US4985585A (en) 1988-03-07 1991-01-15 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process for their preparations
US4996047A (en) 1988-11-02 1991-02-26 Richardson-Vicks, Inc. Sustained release drug-resin complexes
CA2002492A1 (en) 1988-11-11 1990-05-11 Sandra T. A. Malkowska Pharmaceutical ion exchange resin composition
US5133974A (en) 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5290812A (en) 1991-01-18 1994-03-01 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process of preparing the same
US7060854B2 (en) 2003-06-24 2006-06-13 Medicinova, Inc. Process for making polymorphic form A of 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid
US7064146B2 (en) 2003-06-24 2006-06-20 Medicinova, Inc. Pharmaceutical compositions of isolated orthorhombic crystalline 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid and methods of use
KR20070058381A (ko) * 2004-04-27 2007-06-08 메디시노바, 인크. 염증성 질환 치료용 페녹시알킬카르복실 산 유도체
AU2005259864A1 (en) * 2004-06-30 2006-01-12 Combinatorx, Incorporated Methods and reagents for the treatment of metabolic disorders
CN101193656B (zh) * 2005-06-08 2011-03-02 兴和株式会社 甘油三酸酯降低剂
WO2009002746A1 (en) * 2007-06-22 2008-12-31 Decode Genetics Ehf. Dosing schedules of leukotriene synthesis inhibitors for human therapy

Also Published As

Publication number Publication date
CA2917780C (en) 2023-01-24
EP3024454A1 (en) 2016-06-01
BR112016001400A8 (pt) 2020-01-14
EP3024454A4 (en) 2017-03-15
WO2015013395A1 (en) 2015-01-29
KR102352728B1 (ko) 2022-01-18
US20150080471A1 (en) 2015-03-19
US20150031769A1 (en) 2015-01-29
CN105407884A (zh) 2016-03-16
EP3024454B1 (en) 2020-10-21
CA2917780A1 (en) 2015-01-29
BR112016001400A2 (pt) 2017-07-25
CN105407884B (zh) 2019-04-30
KR20160034324A (ko) 2016-03-29
JP6363192B2 (ja) 2018-07-25
BR112016001400B1 (pt) 2023-02-28
US9358217B2 (en) 2016-06-07
JP2016525546A (ja) 2016-08-25

Similar Documents

Publication Publication Date Title
JP6608404B2 (ja) 非アルコール性脂肪性肝疾患及び非アルコール性脂肪性肝炎の処置方法
HUE027711T2 (en) An aqueous formulation of improved stability of (E) -4-carboxystyril-4-chlorobenzylsulfone
ES2843511T3 (es) Métodos para reducir las concentraciones en sangre de triglicéridos, colesterol total y lipoproteínas de baja densidad
JP2022501390A (ja) 化合物及びその用途
TW201929846A (zh) 包含苯基磺醯胺之醫藥組合物及其治療應用
US9498458B2 (en) Method of inhibiting or treating fibrosis
JP2025530781A (ja) 新規のイオン化可能な脂質および脂質ナノ粒子ならびにそれらの使用方法
TW201625543A (zh) 羥吡啶酮衍生物,其醫藥組合物,及其用於發炎性、神經退化性或免疫媒介疾病之治療用途
CA3217719A1 (en) Phenoxyalkylcarboxylic acid derivatives and their use in lowering triglyceride levels
US20150320705A1 (en) Method of inhibiting or treating amyotrophic lateral sclerosis with phenoxyalkylcarboxylic acids
BR112019011789B1 (pt) Compostos de quinona e ácido ascórbico para tratar doença de chagas