BR112015024985A2 - método de refino de ácido quinolínico - Google Patents

método de refino de ácido quinolínico

Info

Publication number
BR112015024985A2
BR112015024985A2 BR112015024985A BR112015024985A BR112015024985A2 BR 112015024985 A2 BR112015024985 A2 BR 112015024985A2 BR 112015024985 A BR112015024985 A BR 112015024985A BR 112015024985 A BR112015024985 A BR 112015024985A BR 112015024985 A2 BR112015024985 A2 BR 112015024985A2
Authority
BR
Brazil
Prior art keywords
quinolinic acid
refining method
acid
acid refining
salt
Prior art date
Application number
BR112015024985A
Other languages
English (en)
Other versions
BR112015024985B1 (pt
Inventor
Ho Lee Chong
Murata Hideki
Sung Lee In
Hun Yu Jae
Un Park Ju
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of BR112015024985A2 publication Critical patent/BR112015024985A2/pt
Publication of BR112015024985B1 publication Critical patent/BR112015024985B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

resumo método de refino de ácido quinolínico a presente invenção refere-se a um método de refino de ácido quinolínico, que inclui as etapas de: preparar uma solução de fermentação que inclui pelo menos um dentre ácido quinolínico e um sal do mesmo; remover células microbianas da solução de fermentação; preparar uma composição ácida que contém pelo menos um dentre ácido quinolínico e um sal do mesmo em uma concentração de saturação ou mais através da adição de um ácido à solução de fermentação; e recuperar um cristal de pelo menos um dentre ácido quinolínico e um sal do mesmo da composição ácida. 1/1
BR112015024985-0A 2013-04-01 2014-03-06 Método de refino de ácido quinolínico BR112015024985B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2013-0035462 2013-04-01
KR1020130035462A KR101395558B1 (ko) 2013-04-01 2013-04-01 퀴놀린산의 정제방법
PCT/KR2014/001833 WO2014163301A1 (ko) 2013-04-01 2014-03-06 퀴놀린산의 정제방법

Publications (2)

Publication Number Publication Date
BR112015024985A2 true BR112015024985A2 (pt) 2017-07-18
BR112015024985B1 BR112015024985B1 (pt) 2021-11-16

Family

ID=50894235

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015024985-0A BR112015024985B1 (pt) 2013-04-01 2014-03-06 Método de refino de ácido quinolínico

Country Status (6)

Country Link
US (1) US9452983B2 (pt)
EP (1) EP2982759B1 (pt)
KR (1) KR101395558B1 (pt)
CN (1) CN105074000B (pt)
BR (1) BR112015024985B1 (pt)
WO (1) WO2014163301A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115032285B (zh) * 2021-03-08 2024-01-02 远大生命科学(武汉)有限公司 一种吲哚喹啉酸有关物质的rt-hplc检测方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537971A (en) * 1981-05-06 1985-08-27 The Hilton-Davis Chemical Co. Process for preparing quinolinic acid
JPS5886090A (ja) * 1981-11-17 1983-05-23 Mitsui Petrochem Ind Ltd ジカルボン酸の分離方法
DE3826041A1 (de) * 1988-07-30 1990-02-08 Ruetgerswerke Ag Verfahren zur herstellung von chinolinsaeure
CN102399182A (zh) * 2010-09-08 2012-04-04 鞍钢股份有限公司 喹啉酸的生产方法
KR101223904B1 (ko) 2011-01-14 2013-01-21 씨제이제일제당 (주) 니코틴산의 제조 방법

Also Published As

Publication number Publication date
EP2982759A4 (en) 2016-08-24
US9452983B2 (en) 2016-09-27
CN105074000A (zh) 2015-11-18
CN105074000B (zh) 2018-12-21
EP2982759B1 (en) 2018-07-18
WO2014163301A1 (ko) 2014-10-09
KR101395558B1 (ko) 2014-05-16
EP2982759A1 (en) 2016-02-10
BR112015024985B1 (pt) 2021-11-16
US20160052885A1 (en) 2016-02-25

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/03/2014, OBSERVADAS AS CONDICOES LEGAIS.