BR112015019264A2 - composições farmacêuticas para o tratamento de helicobacter pylori - Google Patents

composições farmacêuticas para o tratamento de helicobacter pylori

Info

Publication number
BR112015019264A2
BR112015019264A2 BR112015019264A BR112015019264A BR112015019264A2 BR 112015019264 A2 BR112015019264 A2 BR 112015019264A2 BR 112015019264 A BR112015019264 A BR 112015019264A BR 112015019264 A BR112015019264 A BR 112015019264A BR 112015019264 A2 BR112015019264 A2 BR 112015019264A2
Authority
BR
Brazil
Prior art keywords
treatment
pharmaceutical compositions
helicobacter pylori
pylori
infection
Prior art date
Application number
BR112015019264A
Other languages
English (en)
Other versions
BR112015019264B1 (pt
BR112015019264A8 (pt
Inventor
Raday Gilead
Goldberg Guy
Gosselin Patrick
Fathi Reza
Original Assignee
Redhill Biopharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51297592&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112015019264(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Redhill Biopharma Ltd filed Critical Redhill Biopharma Ltd
Publication of BR112015019264A2 publication Critical patent/BR112015019264A2/pt
Publication of BR112015019264A8 publication Critical patent/BR112015019264A8/pt
Publication of BR112015019264B1 publication Critical patent/BR112015019264B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4747Quinolines; Isoquinolines spiro-condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)

Abstract

resumo patente de invenção: "composições farmacêuticas para o tratamento de helicobacter pylori". uma forma de dosagem sólida oral simples compreendendo uma primeira composição de dosagem de liberação imediata tendo pelo menos dois agentes antibióticos e uma segunda composição de dosagem de liberação retardada tendo um inibidor de bomba de prótons é aqui provida. a forma de dosagem sólida oral simples de acordo com alguns aspectos da invenção pode ser usada para o tratamento de distúrbios associados com infecção por h. pylori ou a prevenção de recorrência de distúrbios associados com infecção por h. pylori.
BR112015019264-5A 2013-02-13 2014-02-12 Cápsulas para o tratamento de helicobacter pylori e seu uso BR112015019264B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361764401P 2013-02-13 2013-02-13
US201361764385P 2013-02-13 2013-02-13
US61/764,401 2013-02-13
US61/764,385 2013-02-13
PCT/US2014/016071 WO2014127025A1 (en) 2013-02-13 2014-02-12 Pharmaceutical compositions for the treatment of helicobacter pylori

Publications (3)

Publication Number Publication Date
BR112015019264A2 true BR112015019264A2 (pt) 2017-07-18
BR112015019264A8 BR112015019264A8 (pt) 2019-11-12
BR112015019264B1 BR112015019264B1 (pt) 2021-08-24

Family

ID=51297592

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015019264-5A BR112015019264B1 (pt) 2013-02-13 2014-02-12 Cápsulas para o tratamento de helicobacter pylori e seu uso

Country Status (26)

Country Link
US (8) US9050263B2 (pt)
EP (1) EP2956149B1 (pt)
JP (1) JP6494529B2 (pt)
KR (1) KR102062357B1 (pt)
CN (2) CN105163743A (pt)
AU (1) AU2014216373B2 (pt)
BR (1) BR112015019264B1 (pt)
CA (1) CA2900763C (pt)
CL (1) CL2015002253A1 (pt)
CY (1) CY1122113T1 (pt)
DK (1) DK2956149T3 (pt)
ES (1) ES2744406T3 (pt)
HK (1) HK1217645A1 (pt)
HR (1) HRP20191559T1 (pt)
HU (1) HUE052411T2 (pt)
IL (1) IL240387B (pt)
MX (1) MX368536B (pt)
NZ (1) NZ711754A (pt)
PH (1) PH12015501783A1 (pt)
PL (1) PL2956149T3 (pt)
PT (1) PT2956149T (pt)
RU (1) RU2671400C2 (pt)
SG (1) SG11201506318QA (pt)
SI (1) SI2956149T1 (pt)
UA (1) UA120249C2 (pt)
WO (1) WO2014127025A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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KR102062357B1 (ko) 2013-02-13 2020-01-03 레드힐 바이오파마 엘티디 헬리코박터 파일로리 치료용 약제학적 조성물
KR101884230B1 (ko) * 2016-02-29 2018-08-01 주식회사 유영제약 에소메프라졸을 포함하는 제제
JP2018149269A (ja) * 2017-01-18 2018-09-27 マッカイ メディカル ファンデーション ザ プレスビュテロス チャーチ イン タイワン マッカイ メモリアル ホスピタル 消化管感染症に対する管腔内治療システム
EP3551186A4 (en) * 2017-10-15 2020-08-19 The Center for Digestive Diseases COMPOSITIONS AND METHODS FOR THE TREATMENT, IMPROVEMENT AND PREVENTION OF H. PYLORI INFECTIONS
CN108497546B (zh) * 2018-03-22 2021-03-19 宝可科技(上海)有限公司 一种烟用添加剂及其制备方法和用途
CN110354125A (zh) * 2019-08-12 2019-10-22 珠海赛隆药业股份有限公司 一种治疗幽门螺杆菌感染的组合物及其制剂和用途
US11878011B2 (en) 2020-05-07 2024-01-23 Redhill Biopharma Ltd. Method for eradicating Helicobacter pylori infection in patients regardless of body mass index
KR20230150745A (ko) * 2022-04-22 2023-10-31 한국생명공학연구원 헬리코박터 파일로리에 의한 위 점막 손상 관련 질환의 예방 또는 치료용 약학적 조성물
CN117398360B (zh) * 2023-12-14 2024-03-15 山东齐都药业有限公司 治疗幽门螺杆菌的复方制剂胶囊及其制备方法

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Also Published As

Publication number Publication date
IL240387B (en) 2020-02-27
PT2956149T (pt) 2019-09-20
US11135172B2 (en) 2021-10-05
HK1217645A1 (zh) 2017-01-20
DK2956149T3 (da) 2019-09-09
US20240325313A1 (en) 2024-10-03
ES2744406T3 (es) 2020-02-25
KR20150118176A (ko) 2015-10-21
JP2016508516A (ja) 2016-03-22
US10898439B2 (en) 2021-01-26
CN105163743A (zh) 2015-12-16
PH12015501783B1 (en) 2015-12-07
SI2956149T1 (sl) 2019-11-29
NZ711754A (en) 2020-05-29
KR102062357B1 (ko) 2020-01-03
RU2015138708A (ru) 2017-03-17
CY1122113T1 (el) 2020-11-25
SG11201506318QA (en) 2015-09-29
US20190336451A1 (en) 2019-11-07
HRP20191559T1 (hr) 2019-11-29
CA2900763C (en) 2021-04-06
EP2956149B1 (en) 2019-06-19
AU2014216373A1 (en) 2015-08-27
US9050263B2 (en) 2015-06-09
BR112015019264B1 (pt) 2021-08-24
MX368536B (es) 2019-10-07
PL2956149T3 (pl) 2020-03-31
BR112015019264A8 (pt) 2019-11-12
US9603806B2 (en) 2017-03-28
PH12015501783A1 (en) 2015-12-07
WO2014127025A1 (en) 2014-08-21
US11931463B2 (en) 2024-03-19
US20150044283A1 (en) 2015-02-12
RU2671400C2 (ru) 2018-10-31
UA120249C2 (uk) 2019-11-11
CN109893516A (zh) 2019-06-18
EP2956149A4 (en) 2016-10-12
US10238606B2 (en) 2019-03-26
US20160235681A1 (en) 2016-08-18
EP2956149A1 (en) 2015-12-23
US9498445B2 (en) 2016-11-22
JP6494529B2 (ja) 2019-04-03
CA2900763A1 (en) 2014-08-21
US20220062188A1 (en) 2022-03-03
US20190175512A1 (en) 2019-06-13
HUE052411T2 (hu) 2021-04-28
CL2015002253A1 (es) 2016-07-29
AU2014216373B2 (en) 2017-12-21
IL240387A0 (en) 2015-09-24
MX2015010490A (es) 2015-10-30
US20140227353A1 (en) 2014-08-14
US20170189341A1 (en) 2017-07-06

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