BR112015010703A8 - Uso de uma composição farmacêutica e composição farmacêutica - Google Patents

Uso de uma composição farmacêutica e composição farmacêutica

Info

Publication number
BR112015010703A8
BR112015010703A8 BR112015010703A BR112015010703A BR112015010703A8 BR 112015010703 A8 BR112015010703 A8 BR 112015010703A8 BR 112015010703 A BR112015010703 A BR 112015010703A BR 112015010703 A BR112015010703 A BR 112015010703A BR 112015010703 A8 BR112015010703 A8 BR 112015010703A8
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
pharmaceutical
compositions
tocotrienol
tocotrienols
Prior art date
Application number
BR112015010703A
Other languages
English (en)
Other versions
BR112015010703B1 (pt
BR112015010703A2 (pt
Inventor
Tong Glenn
Original Assignee
Gordagen Pharmaceuticals Pty Ltd
Invictus Biotechnology Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012904937A external-priority patent/AU2012904937A0/en
Application filed by Gordagen Pharmaceuticals Pty Ltd, Invictus Biotechnology Pty Ltd filed Critical Gordagen Pharmaceuticals Pty Ltd
Publication of BR112015010703A2 publication Critical patent/BR112015010703A2/pt
Publication of BR112015010703A8 publication Critical patent/BR112015010703A8/pt
Publication of BR112015010703B1 publication Critical patent/BR112015010703B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

COMPOSIÇÃO FARMACÊUTICA, USOS DE PELO MENOS UM TOCOTRIENOL OU DERIVADO DESTE, E USOS DE UMA COMPOSIÇÃO FARMACÊUTICA. A presente invenção se refere às composições farmacêuticas formuladas para administração transmucosal que incluem pelo menos um tocotrienóis ou derivados destes e os usos destas composições.
BR112015010703-6A 2012-11-13 2013-11-13 uso de uma composição farmacêutica e composição farmacêutica BR112015010703B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2012904937A AU2012904937A0 (en) 2012-11-13 Sublingual and buccal delivery of tocotrienol derivatives as therapeutic agents
AUAU2012904937 2012-11-13
AUAU2012905406 2012-12-11
AU2012905406A AU2012905406A0 (en) 2012-12-11 Sublingual and buccal delivery of tocotrienol derivatives as therapeutic agents
PCT/AU2013/001310 WO2014075135A1 (en) 2012-11-13 2013-11-13 Transmucosal delivery of tocotrienol

Publications (3)

Publication Number Publication Date
BR112015010703A2 BR112015010703A2 (pt) 2017-07-11
BR112015010703A8 true BR112015010703A8 (pt) 2018-08-14
BR112015010703B1 BR112015010703B1 (pt) 2021-02-17

Family

ID=50730398

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015010703-6A BR112015010703B1 (pt) 2012-11-13 2013-11-13 uso de uma composição farmacêutica e composição farmacêutica

Country Status (23)

Country Link
US (2) US10675265B2 (pt)
EP (1) EP2919777B1 (pt)
JP (3) JP6460998B2 (pt)
KR (1) KR20150082109A (pt)
CN (2) CN104582700B (pt)
AU (1) AU2013344817B2 (pt)
BR (1) BR112015010703B1 (pt)
CA (1) CA2891164C (pt)
DK (1) DK2919777T3 (pt)
ES (1) ES2778065T3 (pt)
HK (1) HK1207295A1 (pt)
IL (1) IL238727A0 (pt)
IN (1) IN2015DN04006A (pt)
MY (1) MY177940A (pt)
NZ (1) NZ628963A (pt)
PE (1) PE20151518A1 (pt)
PH (1) PH12015501048A1 (pt)
PL (1) PL2919777T3 (pt)
PT (1) PT2919777T (pt)
RU (1) RU2015120181A (pt)
SG (1) SG11201503640WA (pt)
WO (1) WO2014075135A1 (pt)
ZA (1) ZA201504191B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9897565B1 (en) 2012-09-11 2018-02-20 Aseko, Inc. System and method for optimizing insulin dosages for diabetic subjects
US9171343B1 (en) 2012-09-11 2015-10-27 Aseko, Inc. Means and method for improved glycemic control for diabetic patients
RU2015120181A (ru) * 2012-11-13 2017-01-10 Гордаген Фармасьютикалз Пти Лтд Чресслизистая доставка токотриенола
US9898585B2 (en) 2014-01-31 2018-02-20 Aseko, Inc. Method and system for insulin management
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
WO2016069475A1 (en) 2014-10-27 2016-05-06 Aseko, Inc. Subcutaneous outpatient management
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
US20170128412A1 (en) * 2015-08-11 2017-05-11 Satoru Sugiyama System and method for improved blood circulation and maintaining mitochondrial energy production
JP6858751B2 (ja) 2015-08-20 2021-04-14 アセコー インコーポレイテッド 糖尿病管理療法アドバイザ
WO2019032685A1 (en) * 2017-08-08 2019-02-14 Robert John Petcavich FORMULATIONS FOR THE CONTRIBUTION OF TREHALOSE STIMULATING AUTOPHAGIA
AU2021392309A1 (en) * 2020-12-04 2023-07-20 Invictus Biotechnology Pty Ltd Transmucosal delivery of tocotrienols

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07504887A (ja) * 1991-11-22 1995-06-01 リポジェニックス,インコーポレイテッド トコトリエノールおよびトコトリエノール様化合物ならびにこれらを使用する方法
JPH0892050A (ja) 1994-09-27 1996-04-09 Lion Corp 消臭剤及び口腔用組成物
JP4271742B2 (ja) * 1997-08-07 2009-06-03 エーザイ・アール・アンド・ディー・マネジメント株式会社 免疫機能改善剤
US6264981B1 (en) 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
JP2001342133A (ja) * 2000-03-31 2001-12-11 Eisai Co Ltd γ―トコトリエノール含有利尿剤
AU2001242811B2 (en) * 2000-03-31 2005-07-14 Eisai R&D Management Co., Ltd. Diuretics containing gamma-tocotrienol
JP2002037727A (ja) 2000-07-26 2002-02-06 Eisai Co Ltd 脂溶性薬物を配合した速崩性固形製剤及びその製造方法
JP4693140B2 (ja) * 2000-10-06 2011-06-01 富士化学工業株式会社 トコトリエノール含有医薬用剤
US6608103B2 (en) * 2001-02-08 2003-08-19 Fuji Chemical Industry Co., Ltd. Inhibitor for neovasculation, cell multiplication, lumen formation and FGF
JP4447198B2 (ja) * 2001-02-08 2010-04-07 富士化学工業株式会社 トコトリエノールを有効成分とする血管新生阻害剤、細胞増殖阻害剤、管腔形成阻害剤及びfgf阻害剤並びに食品或いは食品添加物
US7919525B2 (en) 2003-02-14 2011-04-05 Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Radiation protection by gamma-tocotrienol
EP1617724B1 (en) * 2003-04-10 2014-08-20 Barrie Tan Annatto extract compositions including tocotrienols and tocopherols and methods of use
US20050209315A1 (en) * 2004-03-20 2005-09-22 Papas Andreas M Bioavailable nutritional supplement and method of treatment of malabsorption
ATE491447T1 (de) * 2004-05-26 2011-01-15 Kgk Synergize Inc Flavonoide und tocotrienole enthaltende zusammensetzungen und deren verwendungen
CN1775289B (zh) 2004-11-15 2011-08-24 杭州赛诺菲民生健康药业有限公司 多维生素口腔崩解片制剂及其制备方法
ES2586032T3 (es) 2008-03-28 2016-10-11 Hale Biopharma Ventures, Llc Administración de composiciones de benzodiazepinas
WO2009126866A2 (en) * 2008-04-10 2009-10-15 Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Delta-tocotrienol as a radioprotective countermeasure agent
CA2761538A1 (en) 2009-05-20 2010-12-23 Lingual Consegna Pty Ltd Buccal and/or sublingual therapeutic formulation
CA2765771A1 (en) 2009-06-25 2010-12-29 Ampere Life Sciences, Inc. Treatment of pervasive developmental disorders with tocotrienols or tocotrienol enriched extracts
MX337990B (es) * 2009-08-26 2016-03-30 Edison Pharmaceuticals Inc Metodos para la prevencion y tratamiento de isquemia cerebral.
US20110172312A1 (en) 2009-12-31 2011-07-14 Miller Guy M Treatment of leigh syndrome and leigh-like syndrome with tocotrienol quinones
CA2795726A1 (en) * 2010-04-06 2011-10-13 Edison Pharmaceuticals, Inc. Treatment of ataxia telangiectasia
WO2012068552A1 (en) * 2010-11-19 2012-05-24 Edison Pharmaceuticals, Inc. Methods for improving blood glucose control
BR112013020841B8 (pt) 2011-02-18 2021-11-30 Ying Ko Sai Processo para preparar produtos que compreendem ativos estabilizados e composições que compreendem os mesmos
WO2012174158A2 (en) 2011-06-14 2012-12-20 Hale Biopharma Ventures, Llc Administration of benzodiazepine
RU2015120181A (ru) * 2012-11-13 2017-01-10 Гордаген Фармасьютикалз Пти Лтд Чресслизистая доставка токотриенола

Also Published As

Publication number Publication date
CN104582700A (zh) 2015-04-29
JP2021008509A (ja) 2021-01-28
ES2778065T3 (es) 2020-08-07
EP2919777B1 (en) 2020-01-08
MY177940A (en) 2020-09-28
RU2015120181A (ru) 2017-01-10
AU2013344817B2 (en) 2015-09-17
EP2919777A1 (en) 2015-09-23
SG11201503640WA (en) 2015-06-29
PT2919777T (pt) 2020-03-30
JP6460998B2 (ja) 2019-01-30
CN104582700B (zh) 2021-01-05
ZA201504191B (en) 2016-11-30
JP6978392B2 (ja) 2021-12-08
IN2015DN04006A (pt) 2015-10-02
CA2891164A1 (en) 2014-05-22
CN112451518A (zh) 2021-03-09
CA2891164C (en) 2021-02-09
PH12015501048A1 (en) 2015-07-27
WO2014075135A1 (en) 2014-05-22
PL2919777T3 (pl) 2020-07-13
JP2016503407A (ja) 2016-02-04
JP2019031504A (ja) 2019-02-28
US10675265B2 (en) 2020-06-09
NZ628963A (en) 2017-02-24
HK1207295A1 (en) 2016-01-29
PE20151518A1 (es) 2015-11-25
BR112015010703B1 (pt) 2021-02-17
US20150265570A1 (en) 2015-09-24
AU2013344817A1 (en) 2015-02-12
IL238727A0 (en) 2015-06-30
BR112015010703A2 (pt) 2017-07-11
EP2919777A4 (en) 2016-05-18
DK2919777T3 (da) 2020-03-09
US20200246306A1 (en) 2020-08-06
US11331302B2 (en) 2022-05-17
KR20150082109A (ko) 2015-07-15

Similar Documents

Publication Publication Date Title
BR112015010703A8 (pt) Uso de uma composição farmacêutica e composição farmacêutica
MX2018004175A (es) Derivado oxa espiro, su metodo de preparacion, y sus aplicaciones en medicinas.
BR112016012146A2 (pt) Compostos derivados de aminopiridina como inibidores quinase da família tam, composição farmacêutica compreendendo ditos compostos e uso terapêutico dos mesmos
CO2017012995A2 (es) Derivados análogos de heteroarilos/arilo actvos como reguladores nrf2 y composiciones farmacéuticas de los mismos
BR112017022604A2 (pt) composto, composição farmacêutica, uso de um composto e de uma combinação, e, combinação
BR112018007977A2 (pt) inibidores de ferroportina inovadores
BR112018076169A2 (pt) derivados azabenzimidazol como inibidores de pi3k beta
GT201500138A (es) Novedososo derivados de bencimidazol como antagonistas de ep4
BR112015022566A2 (pt) composto e composição farmacêutica
DOP2015000245A (es) Derivados de 3-acetilamino-1 (fenil-heteroaril-aminocarbonil o fenil-heteroaril-carbonilamino) benceno para el tratamiento de desordenes hiperproliferativos
GT201400144A (es) Nuevos derivados de pirrol, su procedimiento de preparación y las composiciones farmacéuticas que los contienen
CL2017001923A1 (es) Derivados de 9h-pirrolo-dipiridina
BR112016028845A2 (pt) composto, composição farmacêutica e uso de um composto
BR112015003655A2 (pt) composto; uso de um composto; e composição farmacêutica
GEP201706623B (en) Pyrrolotriazinone derivatives as pi3k inhibitors
DOP2015000005A (es) Derivados de estra 1,3,5(10), 16 tetraeno 3 sustituidos, métodos para su preparación, preparaciones farmacéuticas que los contienen, así como su uso para la preparación de medicamentos
CO2017007325A2 (es) 2,4 diamino-quinolina sustituida como nuevos agentes anti-cancerigenos
CR20140144A (es) Derivados de estra-1,3,5 (10), 16-tetraen-3-carboxamida, procedimientos para su preparación, preparados farmacéuticos que los contienen, así como su uso para la preparación de medicamentos
BR112017012005A2 (pt) compostos orgânicos
SV2018005760A (es) Derivados de aminotiazol utiles como agentes antiviricos
BR112012009310B8 (pt) composto derivados de 2-oxo-1-pirrolidinil imidazotiadiazol, uso dos mesmos e composição farmacêutica compreendendo os mesmos
UY35906A (es) Novedosos derivados de bencimidazol como ligandos de ep4
BR112017009012A2 (pt) derivados de anel benzo de seis membros como inibidor de dpp-4 e seu uso
CL2014002986A1 (es) Proceso para la preparacion de compuestos derivados de 2-(1-hidroxi-alquil)-cromen-4-ona opticamente puros y opcionalmente sustituidos; compuestos derivados de 2-(1-hidroxi-alquil)-cromen-4-ona; composicion farmaceutica que los comprende; y su uso para preparar compuestos inhibidores de pi3k.
BR112017022158A2 (pt) compostos, composições farmacêuticas e uso de um composto

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B25A Requested transfer of rights approved

Owner name: INVICTUS BIOTECHNOLOGY PTY LTD (AU)

B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI.

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 13/11/2013, OBSERVADAS AS CONDICOES LEGAIS.