BR112015009467A2 - polinucleotídeo isolado que codifica uma proteína dgat1 quimérica, uso de uma célula,célula de planta, planta, parte de planta, propágulo ou progênie, proteína dgat1 quimérica, seu método de produção, e insumo animal ou para biocombustível - Google Patents

polinucleotídeo isolado que codifica uma proteína dgat1 quimérica, uso de uma célula,célula de planta, planta, parte de planta, propágulo ou progênie, proteína dgat1 quimérica, seu método de produção, e insumo animal ou para biocombustível

Info

Publication number
BR112015009467A2
BR112015009467A2 BR112015009467A BR112015009467A BR112015009467A2 BR 112015009467 A2 BR112015009467 A2 BR 112015009467A2 BR 112015009467 A BR112015009467 A BR 112015009467A BR 112015009467 A BR112015009467 A BR 112015009467A BR 112015009467 A2 BR112015009467 A2 BR 112015009467A2
Authority
BR
Brazil
Prior art keywords
dgat1
chimeric
proteins
plant
protein
Prior art date
Application number
BR112015009467A
Other languages
English (en)
Other versions
BR112015009467B1 (pt
Inventor
Chirstina Curran Amy
Charles Taylor David
Marillia Elizabeth-France
Roldan Marissa
John Roberts Nicholas
William Scott Richard
Winichayakul Somrutai
Original Assignee
Agresearch Ltd
National Res Council Of Canada Nrc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agresearch Ltd, National Res Council Of Canada Nrc filed Critical Agresearch Ltd
Publication of BR112015009467A2 publication Critical patent/BR112015009467A2/pt
Publication of BR112015009467B1 publication Critical patent/BR112015009467B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10L—FUELS NOT OTHERWISE PROVIDED FOR; NATURAL GAS; SYNTHETIC NATURAL GAS OBTAINED BY PROCESSES NOT COVERED BY SUBCLASSES C10G, C10K; LIQUEFIED PETROLEUM GAS; ADDING MATERIALS TO FUELS OR FIRES TO REDUCE SMOKE OR UNDESIRABLE DEPOSITS OR TO FACILITATE SOOT REMOVAL; FIRELIGHTERS
    • C10L1/00—Liquid carbonaceous fuels
    • C10L1/02—Liquid carbonaceous fuels essentially based on components consisting of carbon, hydrogen, and oxygen only
    • C10L1/026—Liquid carbonaceous fuels essentially based on components consisting of carbon, hydrogen, and oxygen only for compression ignition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10L—FUELS NOT OTHERWISE PROVIDED FOR; NATURAL GAS; SYNTHETIC NATURAL GAS OBTAINED BY PROCESSES NOT COVERED BY SUBCLASSES C10G, C10K; LIQUEFIED PETROLEUM GAS; ADDING MATERIALS TO FUELS OR FIRES TO REDUCE SMOKE OR UNDESIRABLE DEPOSITS OR TO FACILITATE SOOT REMOVAL; FIRELIGHTERS
    • C10L2200/00—Components of fuel compositions
    • C10L2200/04—Organic compounds
    • C10L2200/0461—Fractions defined by their origin
    • C10L2200/0469—Renewables or materials of biological origin
    • C10L2200/0476—Biodiesel, i.e. defined lower alkyl esters of fatty acids first generation biodiesel
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10L—FUELS NOT OTHERWISE PROVIDED FOR; NATURAL GAS; SYNTHETIC NATURAL GAS OBTAINED BY PROCESSES NOT COVERED BY SUBCLASSES C10G, C10K; LIQUEFIED PETROLEUM GAS; ADDING MATERIALS TO FUELS OR FIRES TO REDUCE SMOKE OR UNDESIRABLE DEPOSITS OR TO FACILITATE SOOT REMOVAL; FIRELIGHTERS
    • C10L2270/00—Specifically adapted fuels
    • C10L2270/02—Specifically adapted fuels for internal combustion engines
    • C10L2270/026—Specifically adapted fuels for internal combustion engines for diesel engines, e.g. automobiles, stationary, marine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/0102—Diacylglycerol O-acyltransferase (2.3.1.20)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

abstract the invention provides chimeric dgat1 proteins comprising: a) at their n-terminal ends, an n-terminal portion of a first dgat1 protein, and b) at their c-terminal ends, a c-terminal portion of a second dgat1 protein. the chimeric dgat proteins show enhanced activity relative to at least one of the first dgat1 protein and the second dgat1 protein. the chimeric dgat1 proteins of the invention can be expressed in cells to increase cellular lipid accumulation and/or modify the cellular lipid profile. the invention also provides polynucleotides encoding the chimeric dgat1 proteins, cells and compositions comprising the polynucleotides or chimeric dgat1 proteins, and methods using the chimeric dgat1 proteins to produce oil. tradução do resumo resumo patente de invenção: "polinucleotídeos e polipeptídeos de aciltransferase aprimorados e métodos de uso". a presente invenção fornece proteínas dgat1 quiméricas que compreendem: a) em suas extremidades n-terminal, uma porção n-terminal de uma primeira proteína dgat1 e b) em suas extremidades c-terminal, uma porção c-terminal de uma segunda proteína dgat1. as proteínas dgat quiméricas mostram atividade aprimorada em relação a pelo menos uma dentre a primeira proteína dgat1 e a segunda proteína dgat1. as proteínas dgat1 quiméricas da presente invenção podem ser expressas em células para aumentar o acúmulo de lipídio celular e/ou para modificar o perfil de lipídio celular. a presente invenção também fornece polinucleotídeos que codificam as proteínas dgat1 quiméricas, células e composições que compreendem os polinucleotídeos ou as proteínas dgat1 quiméricas e métodos que usam as proteínas dgat1 quiméricas para produzir óleo.
BR112015009467-8A 2012-10-30 2013-10-22 Proteína dgat1 quimérica e seu método de produção, uso de uma célula, célula de planta, planta, parte de planta, propágulo ou progênie expressando uma proteína dgat1 quimérica, e método para produzir triacilglicerídeo (tag) BR112015009467B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261720119P 2012-10-30 2012-10-30
US61/720,119 2012-10-30
PCT/IB2013/059526 WO2014068439A2 (en) 2012-10-30 2013-10-22 Improved acyltransferase polynucleotides, polypeptides, and methods of use

Publications (2)

Publication Number Publication Date
BR112015009467A2 true BR112015009467A2 (pt) 2017-11-14
BR112015009467B1 BR112015009467B1 (pt) 2022-07-19

Family

ID=50628190

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015009467-8A BR112015009467B1 (pt) 2012-10-30 2013-10-22 Proteína dgat1 quimérica e seu método de produção, uso de uma célula, célula de planta, planta, parte de planta, propágulo ou progênie expressando uma proteína dgat1 quimérica, e método para produzir triacilglicerídeo (tag)

Country Status (13)

Country Link
US (1) US9896694B2 (pt)
EP (1) EP2914726B1 (pt)
CN (1) CN104903451B (pt)
AR (1) AR093290A1 (pt)
AU (1) AU2013340445B2 (pt)
BR (1) BR112015009467B1 (pt)
CA (1) CA2889985C (pt)
ES (1) ES2715327T3 (pt)
IN (1) IN2015DN03964A (pt)
MX (1) MX354445B (pt)
NZ (1) NZ706834A (pt)
PL (1) PL2914726T3 (pt)
WO (1) WO2014068439A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2914725A4 (en) 2012-10-30 2016-04-20 Agres Ltd NOVEL POLYNUCLEOTIDES WITH ACYLTRANSFERASE ACTIVITY, POLYPEPTIDES AND METHODS OF USE
EP2914727A4 (en) 2012-10-30 2016-04-20 Agres Ltd IMPROVED ACYLTRANSFERASE POLYNUCLEOTIDES, POLYPEPTIDES AND METHODS OF USE
NZ708313A (en) 2012-12-21 2019-08-30 Nz Inst Plant & Food Res Ltd Regulation of gene expression via uorf of gdp-l-galactose phosphorylase (ggp) gene
BR112016030971B1 (pt) 2014-07-07 2022-09-27 Commonwealth Scientific And Industrial Research Organisation Processo para produzir um produto de óleo e processo para produzir um produto de óleo a partir do óleo da planta
CN110462043A (zh) 2016-09-02 2019-11-15 联邦科学技术研究组织 具有修饰的性状的植物
WO2022246387A1 (en) * 2021-05-17 2022-11-24 Pioneer Hi-Bred International, Inc. Modified seed oil content in plants
WO2023111871A1 (en) * 2021-12-16 2023-06-22 Agresearch Limited Modified acyltransferase polynucleotides, polypeptides, and methods of use

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753475A (en) 1985-01-17 1998-05-19 Calgene, Inc. Methods and compositions for regulated transcription and expression of heterologous genes
US4943674A (en) 1987-05-26 1990-07-24 Calgene, Inc. Fruit specific transcriptional factors
US4795855A (en) 1985-11-14 1989-01-03 Joanne Fillatti Transformation and foreign gene expression with woody species
US5750871A (en) 1986-05-29 1998-05-12 Calgene, Inc. Transformation and foreign gene expression in Brassica species
US5188958A (en) 1986-05-29 1993-02-23 Calgene, Inc. Transformation and foreign gene expression in brassica species
US5187073A (en) 1986-06-30 1993-02-16 The University Of Toledo Process for transforming gramineae and the products thereof
US5177010A (en) 1986-06-30 1993-01-05 University Of Toledo Process for transforming corn and the products thereof
US5004863B2 (en) 1986-12-03 2000-10-17 Agracetus Genetic engineering of cotton plants and lines
US5416011A (en) 1988-07-22 1995-05-16 Monsanto Company Method for soybean transformation and regeneration
US5639952A (en) 1989-01-05 1997-06-17 Mycogen Plant Science, Inc. Dark and light regulated chlorophyll A/B binding protein promoter-regulatory system
US5086169A (en) 1989-04-20 1992-02-04 The Research Foundation Of State University Of New York Isolated pollen-specific promoter of corn
US5837848A (en) 1990-03-16 1998-11-17 Zeneca Limited Root-specific promoter
US5498830A (en) 1990-06-18 1996-03-12 Monsanto Company Decreased oil content in plant seeds
ATE191931T1 (de) 1990-11-23 2000-05-15 Plant Genetic Systems Nv Verfahren zur transformation monokotyler pflanzen
EP0604662B1 (en) 1992-07-07 2008-06-18 Japan Tobacco Inc. Method of transforming monocotyledon
ATE147434T1 (de) 1992-07-09 1997-01-15 Pioneer Hi Bred Int Pollen spezifische polygalacturonase gen aus mais
CA2140910C (en) 1992-07-27 1999-03-23 Jeffrey A. Townsend An improved method of agrobacterium-mediated transformation of cultured soybean cells
US5545169A (en) 1993-04-01 1996-08-13 Yarger; Richard J. Laparoscopic delivery device
DK77393D0 (da) 1993-06-29 1993-06-29 Novo Nordisk As Aktivering af enzymer
WO1995015678A1 (en) 1993-12-09 1995-06-15 The Texas A & M University System Agrobacterium tumefaciens transformation of musa species
GB9421286D0 (en) 1994-10-21 1994-12-07 Danisco Promoter
US5536653A (en) 1994-11-04 1996-07-16 Monsanto Company Tomato fruit promoters
US5846797A (en) 1995-10-04 1998-12-08 Calgene, Inc. Cotton transformation
GB9606062D0 (en) 1996-03-22 1996-05-22 Zeneca Ltd Promoters
US6127179A (en) 1996-04-17 2000-10-03 Dellapenna; Dean Gene promoter for tomato fruit
DE19644478A1 (de) 1996-10-25 1998-04-30 Basf Ag Blattspezifische Expression von Genen in transgenen Pflanzen
US5981840A (en) 1997-01-24 1999-11-09 Pioneer Hi-Bred International, Inc. Methods for agrobacterium-mediated transformation
US5952543A (en) 1997-02-25 1999-09-14 Dna Plant Technology Corporation Genetically transformed pineapple plants and methods for their production
US5968830A (en) 1997-03-28 1999-10-19 Mississippi State University Soybean transformation and regeneration methods
CA2292766A1 (en) 1997-06-05 1998-12-10 Calgene Llc Diacylglycerol acyl transferase proteins
US6037522A (en) 1998-06-23 2000-03-14 Rhone-Poulenc Agro Agrobacterium-mediated transformation of monocots
US6344548B1 (en) 1998-06-24 2002-02-05 The Regents Of The University Of California Diacylglycerol o-acyltransferase
US7135617B2 (en) 1998-07-02 2006-11-14 Calgene Llc Diacylglycerol acyl transferase proteins
EP1098962B1 (en) 1998-07-02 2009-09-09 Calgene LLC Diacylglycerol acyl transferase proteins
US6100077A (en) 1998-10-01 2000-08-08 The Trustees Of Columbia University In The City Of New York Isolation of a gene encoding diacylglycerol acyltransferase
EP1135473A2 (en) 1998-12-02 2001-09-26 E.I. Dupont De Nemours And Company Sequenzes of a putative plant diacylglycerol acyltransferases
US6342657B1 (en) 1999-05-06 2002-01-29 Rhone-Poulenc Agro Seed specific promoters
US7560542B2 (en) 1999-05-07 2009-07-14 Monsanto Technology Llc Nucleic acid molecule SEQ ID NO. 68811 and other molecules associated with plants
US7642346B2 (en) 1999-08-27 2010-01-05 Sembiosys Genetics Inc. Flax seed specific promoters
HUP0204341A3 (en) 2000-01-21 2005-09-28 Pioneer Hi Bred Int Novel root-preferred promoter elements and methods of use
AU2001291656A1 (en) 2000-06-30 2002-01-08 Willem Broekaert Gene silencing vector
US7081565B2 (en) 2000-12-01 2006-07-25 Board Of Trustees Operating Michigan State University Plant seed specific promoters
US20040067506A1 (en) 2000-12-04 2004-04-08 Ben Scheres Novel root specific promoter driving the expression of a novel lrr receptor-like kinase
EP1256629A1 (en) 2001-05-11 2002-11-13 Société des Produits Nestlé S.A. Leaf specifc gene promoter of coffee
KR20050037563A (ko) 2002-07-31 2005-04-22 몬산토 테크놀로지 엘엘씨 디아실글리세롤 아실트랜스퍼라제 핵산 서열 및 연관된 산물
US7371928B2 (en) 2002-11-11 2008-05-13 Korea Chungang Educational Foundation Plant seed-specific expression promoter derived from sesame and seed-specific expression vector comprising the promoter
US7267976B2 (en) * 2003-07-02 2007-09-11 E.I. Du Pont De Nemours And Company Acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous yeasts
KR100537955B1 (ko) 2003-10-29 2005-12-20 학교법인고려중앙학원 꽃가루 특이적 유전자 발현 프로모터
EP1528104A1 (en) 2003-11-03 2005-05-04 Biogemma MEG1 endosperm-specific promoters and genes
WO2005100575A2 (en) 2004-04-14 2005-10-27 Bayer Bioscience N.V. Rice pollen-specific promoters and uses thereof
US7273746B2 (en) 2004-11-04 2007-09-25 E.I. Dupont De Nemours And Company Diacylglycerol acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
MY187548A (en) 2005-06-13 2021-09-29 Government Of Malaysia As Represented By The Mini Of Science Tehnology And Innovation Malaysia Leaf-specific chlorophyll a/b binding protein promoter
EP2730656A1 (en) * 2007-05-24 2014-05-14 E. I. du Pont de Nemours and Company Soybean meal from beans having DGAT genes from yarrowia lipolytica for increased seed storage lipid production and altered fatty acid profiles in soybean
US8299318B2 (en) 2007-07-05 2012-10-30 Ceres, Inc. Nucleotide sequences and corresponding polypeptides conferring modulated plant characteristics
US8362325B2 (en) 2007-10-03 2013-01-29 Ceres, Inc. Nucleotide sequences and corresponding polypeptides conferring modulated plant characteristics
AU2009248931A1 (en) * 2008-05-23 2009-11-26 E. I. Du Pont De Nemours And Company Novel DGAT genes for increased seed storage lipid production and altered fatty acid profiles in oilseed plants
WO2011048119A2 (en) 2009-10-20 2011-04-28 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Methods and means to alter lipid biosynthesis by targeting multiple enzymes to suborganelle domains
TW201127957A (en) 2009-10-30 2011-08-16 Agres Ltd Modified oil encapsulating proteins and uses thereof
US8809026B2 (en) * 2011-12-27 2014-08-19 Commonwealth Scientific And Industrial Research Organisation Processes for producing lipids
EP2914725A4 (en) 2012-10-30 2016-04-20 Agres Ltd NOVEL POLYNUCLEOTIDES WITH ACYLTRANSFERASE ACTIVITY, POLYPEPTIDES AND METHODS OF USE
EP2914727A4 (en) 2012-10-30 2016-04-20 Agres Ltd IMPROVED ACYLTRANSFERASE POLYNUCLEOTIDES, POLYPEPTIDES AND METHODS OF USE

Also Published As

Publication number Publication date
BR112015009467B1 (pt) 2022-07-19
CA2889985C (en) 2022-09-06
CA2889985A1 (en) 2014-05-08
WO2014068439A2 (en) 2014-05-08
US20150284736A1 (en) 2015-10-08
AU2013340445B2 (en) 2019-08-22
CN104903451B (zh) 2020-12-01
US9896694B2 (en) 2018-02-20
AU2013340445A1 (en) 2015-05-07
EP2914726A4 (en) 2016-05-18
WO2014068439A3 (en) 2014-07-17
PL2914726T3 (pl) 2019-06-28
IN2015DN03964A (pt) 2015-10-02
MX354445B (es) 2018-03-06
ES2715327T3 (es) 2019-06-03
CN104903451A (zh) 2015-09-09
EP2914726A2 (en) 2015-09-09
MX2015005271A (es) 2015-10-29
NZ706834A (en) 2019-04-26
EP2914726B1 (en) 2018-12-05
AR093290A1 (es) 2015-05-27

Similar Documents

Publication Publication Date Title
BR112015009467A2 (pt) polinucleotídeo isolado que codifica uma proteína dgat1 quimérica, uso de uma célula,célula de planta, planta, parte de planta, propágulo ou progênie, proteína dgat1 quimérica, seu método de produção, e insumo animal ou para biocombustível
BR112015009455A2 (pt) polinucleotídeo isolado, uso de uma célula, célula de planta, planta, parte de planta, propágulo ou progênie, proteína dgat1 de planta modificada, seu método de produção, matéria-prima animal ou de biocombustível e método para produzir lipídeo
WO2015048339A3 (en) Compositions and formulations for non-human nutrition and methods of production and use thereof
WO2015048333A3 (en) Nutritive polypeptides and formulations thereof, and methods of production and use thereof
BR112017008108A2 (pt) incorporação de aminoácidos não naturais em proteínas
WO2013184938A3 (en) Fusion polypeptides comprising mucin-domain polypeptide linkers
BR112013027130A2 (pt) fitase, sequência de ácido nucleico isolada, célula hospedeira recombinante, organismo de produção recombinante, aditivo de alimentação animal, alimentação animal, e, uso de uma fitase
BR112016002622A2 (pt) meio e processo de cultura celular, polipeptídeo, uso de selênio ou de um sal do mesmo e uso de zinco ou um sal do mesmo
EA201400924A1 (ru) Сконструированные пестицидные белки
BR112016025898A2 (pt) ?drimenol sintases e método para produzir drimenol?
MX2015015274A (es) Ruta de ácido organico novedosa.
AR115695A1 (es) Moléculas proteicas multifuncionales que comprenden decorina y uso de estas
CO2017011431A2 (es) Proteínas de fusión de receptor de factor de crecimiento epidermal variante iii - mesotelina
BR112015013399A2 (pt) polipeptídeo isolado, composição, uso de um polipeptídeo ou de uma composição, métodos para redução do conteúdo de componentes contendo fósforo em um óleo comestível e de produção de um polipeptídeo, constructo de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, e, planta, parte de planta ou célula de planta transgênica transformada com um polinucleotídeo
WO2014068438A3 (en) Novel acyltransferase polynucleotides, polypeptides, and methods of use
WO2014150748A3 (en) Stabilized single human cd4 domains and fusion proteins
IN2013MU02316A (pt)
MY194277A (en) Omega-hydroxylase-related fusion polypeptide variants with improved properties
BR112014003560A2 (pt) polipeptídeo, composição, polinucleotídeo, construto de ácido nucleico ou vetor de expressão, célula hospedeira, métodos de produção de polipeptídeo, para melhoria do valor nutricional de uma alimentação animal, e para o tratamento de proteínas, planta, parte de planta ou célula de planta transgênica, uso de pelo menos um polipeptídeo, aditivo de alimentação animal, e, alimentação animal
WO2012087958A3 (en) Yeast promoters
BR112016025905A2 (pt) drimenol sintases ii
MX2015009867A (es) Mutantes del factor x.
MX2016005572A (es) Uso de monensina para regular la glicosilacion de proteinas recombinantes.
BR112015020253A2 (pt) formulações e métodos para produção aumentada de proteína recombinante
BR112014008315A2 (pt) polipeptídeos da cbh i variante com inibição pelo produto reduzida

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B350 Update of information on the portal [chapter 15.35 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/10/2013, OBSERVADAS AS CONDICOES LEGAIS