BR112016025905A2 - drimenol sintases ii - Google Patents

drimenol sintases ii

Info

Publication number
BR112016025905A2
BR112016025905A2 BR112016025905A BR112016025905A BR112016025905A2 BR 112016025905 A2 BR112016025905 A2 BR 112016025905A2 BR 112016025905 A BR112016025905 A BR 112016025905A BR 112016025905 A BR112016025905 A BR 112016025905A BR 112016025905 A2 BR112016025905 A2 BR 112016025905A2
Authority
BR
Brazil
Prior art keywords
drimenol
polypeptides
present
derivatives
producing
Prior art date
Application number
BR112016025905A
Other languages
English (en)
Other versions
BR112016025905B1 (pt
Inventor
Deguerry Fabienne
Schalk Michel
Haefliger Olivier
He Xiu-Feng
Zhang Yu-Hua
Original Assignee
Firmenich & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firmenich & Cie filed Critical Firmenich & Cie
Publication of BR112016025905A2 publication Critical patent/BR112016025905A2/pt
Publication of BR112016025905B1 publication Critical patent/BR112016025905B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/07—Diphosphoric monoester hydrolases (3.1.7)
    • C12Y301/07007—Drimenol cyclase (3.1.7.7)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

a presente invenção se refere a um método para produzir drimenol e/ou derivados de drimenol colocando-se pelo menos um polipeptídeo em contato com difosfato de farnesila. o método pode ser realizado in vitro ou in vivo. a presente invenção também fornece sequências de aminoácidos de polipeptídeos úteis no método da invenção e ácidos nucleicos que codificam os polipeptídeos da invenção. o método fornece, ainda, células hospedeiras ou organismos geneticamente modificados para expressar os polipeptídeos da invenção e úteis para produzir drimenol e/ou derivados de drimenol.
BR112016025905-0A 2014-05-06 2015-05-06 Drimenol sintases ii BR112016025905B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2014076890 2014-05-06
WOPCT/CN2014/076890 2014-05-06
PCT/EP2015/059988 WO2015169871A2 (en) 2014-05-06 2015-05-06 Drimenol synthases ii

Publications (2)

Publication Number Publication Date
BR112016025905A2 true BR112016025905A2 (pt) 2017-12-12
BR112016025905B1 BR112016025905B1 (pt) 2024-01-09

Family

ID=53483771

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016025905-0A BR112016025905B1 (pt) 2014-05-06 2015-05-06 Drimenol sintases ii

Country Status (9)

Country Link
US (1) US10385363B2 (pt)
EP (1) EP3140410B1 (pt)
JP (1) JP6622220B2 (pt)
CN (1) CN106460014B (pt)
BR (1) BR112016025905B1 (pt)
CA (1) CA2946813A1 (pt)
ES (1) ES2759724T3 (pt)
MX (1) MX2016013955A (pt)
WO (1) WO2015169871A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018005218A (es) * 2015-11-05 2018-08-01 Firmenich & Cie Drimenol sintasas iii.
US11124807B2 (en) 2017-05-03 2021-09-21 Firmenich Sa Sesquiterpene synthases for production of drimenol and mixtures thereof
EP3802804A2 (en) * 2018-05-29 2021-04-14 Firmenich SA Method for producing albicanol compounds
EP3827089A1 (en) * 2018-10-15 2021-06-02 Firmenich SA Method for producing drimanyl acetate compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD3273G2 (ro) * 2006-07-14 2007-10-31 Институт Химии Академии Наук Молдовы Procedeu de obţinere a acetatului drimenolului din 11-monoacetatul driman-8a,11-diolului
JP2013544084A (ja) 2010-10-29 2013-12-12 アリリクス・インコーポレイテッド 改変されたバレンセンシンターゼポリペプチド、コーディング核酸分子およびその使用
CN104053770A (zh) * 2011-10-19 2014-09-17 凯金公司 用于产生肉桂酸内酯和/或补身二醇的方法
US10000773B2 (en) 2011-11-01 2018-06-19 Firmenich Sa Cytochrome P450 and use thereof for the enzymatic oxidation of terpenes
MX2016011465A (es) * 2014-05-21 2016-11-16 Firmenich & Cie Drimenol-sintasas y metodos para producir drimenol.

Also Published As

Publication number Publication date
JP6622220B2 (ja) 2019-12-18
MX2016013955A (es) 2017-04-10
ES2759724T3 (es) 2020-05-12
EP3140410B1 (en) 2019-09-11
US20180251797A1 (en) 2018-09-06
WO2015169871A2 (en) 2015-11-12
CN106460014A (zh) 2017-02-22
BR112016025905B1 (pt) 2024-01-09
EP3140410A2 (en) 2017-03-15
JP2017517251A (ja) 2017-06-29
CA2946813A1 (en) 2015-11-12
WO2015169871A3 (en) 2016-01-14
US10385363B2 (en) 2019-08-20
CN106460014B (zh) 2020-10-02

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Legal Events

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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