BR112015008284B1 - Processo para preparar uma formulação farmacêutica particulada de gosto mascarado - Google Patents
Processo para preparar uma formulação farmacêutica particulada de gosto mascarado Download PDFInfo
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- BR112015008284B1 BR112015008284B1 BR112015008284-0A BR112015008284A BR112015008284B1 BR 112015008284 B1 BR112015008284 B1 BR 112015008284B1 BR 112015008284 A BR112015008284 A BR 112015008284A BR 112015008284 B1 BR112015008284 B1 BR 112015008284B1
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- Prior art keywords
- polymer
- silica
- coating
- particles
- ibuprofen
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/651,829 | 2012-10-15 | ||
| US13/651,829 US8993041B2 (en) | 2012-10-15 | 2012-10-15 | Taste masked active pharmaceutical powder compositions and processes for making them |
| PCT/US2013/064064 WO2014062446A1 (en) | 2012-10-15 | 2013-10-09 | Taste masked active pharmaceutical powder compositions and processes for making them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112015008284A2 BR112015008284A2 (pt) | 2017-07-04 |
| BR112015008284B1 true BR112015008284B1 (pt) | 2022-05-24 |
Family
ID=49447846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015008284-0A BR112015008284B1 (pt) | 2012-10-15 | 2013-10-09 | Processo para preparar uma formulação farmacêutica particulada de gosto mascarado |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8993041B2 (https=) |
| EP (1) | EP2906204B1 (https=) |
| JP (1) | JP6166859B2 (https=) |
| CN (1) | CN104902879B (https=) |
| AR (1) | AR093012A1 (https=) |
| BR (1) | BR112015008284B1 (https=) |
| WO (1) | WO2014062446A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9107851B2 (en) * | 2012-10-15 | 2015-08-18 | New Jersey Institute Of Technology | Solventless mixing process for coating pharmaceutical ingredients |
| US9801820B2 (en) | 2012-11-12 | 2017-10-31 | New Jersey Institute Of Technology | Pharmaceutical core-shell composite powder and processes for making the same |
| CN104587472B (zh) * | 2014-12-31 | 2017-12-15 | 广东国方医药科技有限公司 | 一种含纳米SiO2的包衣剂及其制备方法 |
| JP6067154B1 (ja) * | 2016-01-25 | 2017-01-25 | 株式会社樋口商会 | コーティング粒子の製造方法 |
| KR20250150154A (ko) | 2016-03-15 | 2025-10-17 | 에이서 테라퓨틱스 인크. | 소듐 페닐부티레이트를 포함하는 맛우수한 조성물 및 그의 용도 |
| US11794161B1 (en) | 2018-11-21 | 2023-10-24 | Trucapsol, Llc | Reduced permeability microcapsules |
| US12302933B2 (en) | 2021-06-25 | 2025-05-20 | Trucapsol Llc | Flavor delivery system |
| US12187829B2 (en) | 2021-08-12 | 2025-01-07 | Trucapsol Llc | Environmentally biodegradable microcapsules |
| US11878280B2 (en) | 2022-04-19 | 2024-01-23 | Trucapsol Llc | Microcapsules comprising natural materials |
| US11904288B1 (en) | 2023-02-13 | 2024-02-20 | Trucapsol Llc | Environmentally biodegradable microcapsules |
| US11969491B1 (en) | 2023-02-22 | 2024-04-30 | Trucapsol Llc | pH triggered release particle |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63258809A (ja) * | 1987-04-16 | 1988-10-26 | Towa Yakuhin Kk | 医薬活性成分の放出性にすぐれ、かつ苦味を隠蔽した細粒剤 |
| CA2076983A1 (en) | 1990-04-11 | 1991-10-12 | Robert Wu-Wei Shen | Taste masking of ibuprofen by fluid bed coating |
| JPH08333240A (ja) * | 1995-06-02 | 1996-12-17 | Shin Etsu Chem Co Ltd | 粉末またはペレット状ワックスを用いる無溶媒腸溶性コーティング剤で被覆した腸溶性製剤 |
| GB9515182D0 (en) | 1995-07-24 | 1995-09-20 | Co Ordinated Drug Dev | Improvements in and relating to powders for use in dry powder inhalers |
| JP2000053563A (ja) * | 1998-08-07 | 2000-02-22 | Bayer Yakuhin Ltd | 苦味がマスクされた速放性細粒剤 |
| US6740341B1 (en) * | 1998-11-25 | 2004-05-25 | Cima Labs Inc. | Taste masking rapid release coating system |
| FR2795962B1 (fr) * | 1999-07-08 | 2003-05-09 | Prographarm Laboratoires | Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif |
| GB0010446D0 (en) * | 2000-04-28 | 2000-06-14 | Glaxo Wellcome Kk | Pharmaceutical formulation |
| US7276249B2 (en) | 2002-05-24 | 2007-10-02 | Elan Pharma International, Ltd. | Nanoparticulate fibrate formulations |
| JP2005538105A (ja) * | 2002-07-25 | 2005-12-15 | ファルマシア・コーポレーション | 水不溶性ポリマーおよび水溶性の小孔形成物質からなる２層により被覆された固体剤形の製造方法 |
| US8252370B1 (en) | 2005-10-20 | 2012-08-28 | The United States Of America As Represented By The Secretary Of The Army | Continuous high-speed coating of finely ground particulates |
| DE102005062270A1 (de) * | 2005-12-24 | 2007-06-28 | Bayer Technology Services Gmbh | Geschmacksmaskierung von Pulvern |
| US8550698B2 (en) * | 2006-11-10 | 2013-10-08 | Orion Engineered Carbons Gmbh | Fluidized mixing and blending of nanopowders with secondary gas flow |
| EP2201939A1 (en) | 2008-12-25 | 2010-06-30 | Zentiva Kimyasal Ürünler Sanayi ve Ticaret A.S. | Method for producing coated spiramycin and novel formulations containing the same |
| JP5845172B2 (ja) * | 2009-05-01 | 2016-01-20 | アデア ファーマスーティカルズ，インコーポレイテッド | 高および低用量薬物の組み合わせを含む口腔内崩壊錠組成物 |
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2012
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2013
- 2013-10-09 JP JP2015536854A patent/JP6166859B2/ja active Active
- 2013-10-09 EP EP13779706.4A patent/EP2906204B1/en active Active
- 2013-10-09 CN CN201380053749.6A patent/CN104902879B/zh active Active
- 2013-10-09 BR BR112015008284-0A patent/BR112015008284B1/pt active IP Right Grant
- 2013-10-09 WO PCT/US2013/064064 patent/WO2014062446A1/en not_active Ceased
- 2013-10-15 AR ARP130103730A patent/AR093012A1/es not_active Application Discontinuation
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| WO2014062446A1 (en) | 2014-04-24 |
| US20140106058A1 (en) | 2014-04-17 |
| JP6166859B2 (ja) | 2017-07-19 |
| EP2906204B1 (en) | 2022-09-28 |
| BR112015008284A2 (pt) | 2017-07-04 |
| JP2015533164A (ja) | 2015-11-19 |
| EP2906204A1 (en) | 2015-08-19 |
| US8993041B2 (en) | 2015-03-31 |
| CN104902879B (zh) | 2018-07-17 |
| CN104902879A (zh) | 2015-09-09 |
| AR093012A1 (es) | 2015-05-13 |
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