BR112015004503B1 - composição de liga de mgznca, seu método de produção e implante - Google Patents

composição de liga de mgznca, seu método de produção e implante Download PDF

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Publication number
BR112015004503B1
BR112015004503B1 BR112015004503-0A BR112015004503A BR112015004503B1 BR 112015004503 B1 BR112015004503 B1 BR 112015004503B1 BR 112015004503 A BR112015004503 A BR 112015004503A BR 112015004503 B1 BR112015004503 B1 BR 112015004503B1
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BR
Brazil
Prior art keywords
weight
alloy
less
elements
mgznca
Prior art date
Application number
BR112015004503-0A
Other languages
English (en)
Portuguese (pt)
Other versions
BR112015004503A2 (pt
Inventor
Thomas Imwinkelried
Stefan Beck
Peter Uggowitzer
Joerg Loeffler
Original Assignee
Synthes Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthes Gmbh filed Critical Synthes Gmbh
Publication of BR112015004503A2 publication Critical patent/BR112015004503A2/pt
Publication of BR112015004503B1 publication Critical patent/BR112015004503B1/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/04Metals or alloys
    • A61L27/047Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84Fasteners therefor or fasteners being internal fixation devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02Inorganic materials
    • A61L31/022Metals or alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B21MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21CMANUFACTURE OF METAL SHEETS, WIRE, RODS, TUBES, PROFILES OR LIKE SEMI-MANUFACTURED PRODUCTS OTHERWISE THAN BY ROLLING; AUXILIARY OPERATIONS USED IN CONNECTION WITH METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL
    • B21C23/00Extruding metal; Impact extrusion
    • B21C23/002Extruding materials of special alloys so far as the composition of the alloy requires or permits special extruding methods of sequences
    • CCHEMISTRY; METALLURGY
    • C22METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22CALLOYS
    • C22C23/00Alloys based on magnesium
    • CCHEMISTRY; METALLURGY
    • C22METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22CALLOYS
    • C22C23/00Alloys based on magnesium
    • C22C23/04Alloys based on magnesium with zinc or cadmium as the next major constituent
    • CCHEMISTRY; METALLURGY
    • C22METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22FCHANGING THE PHYSICAL STRUCTURE OF NON-FERROUS METALS AND NON-FERROUS ALLOYS
    • C22F1/00Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working
    • C22F1/06Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of magnesium or alloys based thereon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/12Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Materials Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Metallurgy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Thermal Sciences (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Powder Metallurgy (AREA)
BR112015004503-0A 2012-08-31 2013-08-29 composição de liga de mgznca, seu método de produção e implante BR112015004503B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261695621P 2012-08-31 2012-08-31
US61/695,621 2012-08-31
US13/827,008 US9469889B2 (en) 2012-08-31 2013-03-14 Ultrapure magnesium alloy with adjustable degradation rate
US13/827,008 2013-03-14
PCT/US2013/057294 WO2014036262A1 (en) 2012-08-31 2013-08-29 Ultrapure magnesium alloy with adjustable degradation rate

Publications (2)

Publication Number Publication Date
BR112015004503A2 BR112015004503A2 (pt) 2017-07-04
BR112015004503B1 true BR112015004503B1 (pt) 2021-03-02

Family

ID=49162261

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015004503-0A BR112015004503B1 (pt) 2012-08-31 2013-08-29 composição de liga de mgznca, seu método de produção e implante

Country Status (10)

Country Link
US (2) US9469889B2 (https=)
EP (1) EP2890824B1 (https=)
JP (2) JP6752575B2 (https=)
KR (1) KR102275471B1 (https=)
CN (2) CN111304504A (https=)
BR (1) BR112015004503B1 (https=)
CA (1) CA2883268C (https=)
IN (1) IN2015DN01751A (https=)
TW (1) TWI640638B (https=)
WO (1) WO2014036262A1 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109022980A (zh) 2012-06-26 2018-12-18 百多力股份公司 镁合金、其生产方法及其用途
KR102246885B1 (ko) 2012-06-26 2021-05-03 바이오트로닉 아게 마그네슘 합금, 이의 제조방법 및 이의 용도
ES2913105T3 (es) 2012-06-26 2022-05-31 Biotronik Ag Aleación de magnesio, método para la producción de la misma y uso de la misma
AU2013283537A1 (en) 2012-06-26 2014-11-06 Biotronik Ag Magnesium-zinc-calcium alloy, method for production thereof, and use thereof
US9469889B2 (en) 2012-08-31 2016-10-18 DePuy Synthes Products, Inc. Ultrapure magnesium alloy with adjustable degradation rate
US9593397B2 (en) * 2013-03-14 2017-03-14 DePuy Synthes Products, Inc. Magnesium alloy with adjustable degradation rate
WO2014159328A1 (en) 2013-03-14 2014-10-02 DePuy Synthes Products, LLC Magnesium alloy with adjustable degradation rate
US20160206788A1 (en) * 2013-06-12 2016-07-21 The Regents Of The University Of California Biomimetic interfaces for biodegradable metallic implants
WO2016033312A1 (en) * 2014-08-27 2016-03-03 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Magnesium enhanced/induced bone formation
TWI610651B (zh) * 2014-11-20 2018-01-11 財團法人金屬工業研究發展中心 鎂合金縫合釘
CN105568103A (zh) * 2016-01-04 2016-05-11 青岛工学院 一种可降解生物医用镁合金
CN107227422A (zh) * 2016-03-25 2017-10-03 武汉理工大学 一种高强度盐水可溶性镁合金材料及其制备方法
KR20170115429A (ko) 2016-04-07 2017-10-17 랩앤피플주식회사 생체분해성 금속을 이용한 마이크로 니들
WO2017176077A1 (ko) * 2016-04-07 2017-10-12 랩앤피플주식회사 생체분해성 금속을 이용한 마이크로 니들
KR101888091B1 (ko) * 2016-10-31 2018-08-14 유앤아이 주식회사 생체분해 마그네슘 합금 및 그 제조방법
JPWO2018109947A1 (ja) * 2016-12-16 2019-06-24 三協立山株式会社 マグネシウム合金の製造方法およびマグネシウム合金
CN107190192B (zh) * 2017-07-10 2018-10-02 太原理工大学 一种可吸收生物医用高强韧耐蚀镁合金材料及其制备方法
CN107236886B (zh) * 2017-07-10 2018-09-07 太原理工大学 一种医用可降解高强韧耐蚀多元Mg-Zn-Y-Ca-Zr合金及其制备方法
CN107523732B (zh) * 2017-08-15 2019-04-05 太原科技大学 一种含Na快速降解镁合金及其制备方法
CN108425051A (zh) * 2018-03-29 2018-08-21 江苏理工学院 一种生物医用Mg-Sn-Zn-Ca镁合金及其制备方法
CN109112377B (zh) * 2018-11-09 2020-06-02 吉林大学 一种耐蚀生物医用镁合金及其制备方法和应用
CN110438380B (zh) * 2019-08-13 2021-02-26 中南大学 一种耐热阻燃镁合金及其形变热处理方法
EP4022104A4 (en) * 2019-08-26 2023-09-27 Ohio State Innovation Foundation OBJECTS BASED ON MAGNESIUM ALLOY AND ASSOCIATED METHODS OF MANUFACTURING AND USE
CN110604632A (zh) * 2019-10-21 2019-12-24 中国人民解放军南部战区海军第一医院 生物可降解美容提拉线及其制备方法
CN111388764B (zh) * 2020-04-03 2024-06-04 北京联合大学 一种可降解金属吻合钉及制备方法
US20230201416A1 (en) * 2020-04-21 2023-06-29 National University Corporation Kumamoto University Implant magnesium alloy, bone fixture, method of manufacturing implant magnesium alloy, and method of manufacturing bone fixture device
ES2982681T3 (es) 2020-12-31 2024-10-17 Bioretec Oy Un implante que comprende aleación de magnesio y un método para la preparación del mismo
JP2021079133A (ja) * 2021-02-10 2021-05-27 キュースリー メディカル デヴァイシズ リミテッドQ3 Medical Devices Limited 生体分解性支持デバイス

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3320055A (en) 1964-08-19 1967-05-16 Dow Chemical Co Magnesium-base alloy
AU2002950563A0 (en) * 2002-08-02 2002-09-12 Commonwealth Scientific And Industrial Research Organisation Age-Hardenable, Zinc-Containing Magnesium Alloys
CN1743486A (zh) 2004-08-31 2006-03-08 唐智荣 镁元素为基质的合金及作为骨折内固定器的应用
CN100400114C (zh) * 2005-04-30 2008-07-09 中国科学院金属研究所 可控降解速率的生物医用植入材料及其应用
WO2007058276A1 (ja) 2005-11-16 2007-05-24 National Institute For Materials Science マグネシウム系生分解性金属材料
CN100368028C (zh) 2005-12-22 2008-02-13 上海交通大学 生物体内可吸收的Mg-Zn两元镁合金材料
CN1792383A (zh) * 2005-12-22 2006-06-28 上海交通大学 生物体内可吸收的Mg-Zn-Ca三元镁合金材料
DE102006015457A1 (de) 2006-03-31 2007-10-04 Biotronik Vi Patent Ag Magnesiumlegierung und dazugehöriges Herstellungsverfahren
KR100929133B1 (ko) 2006-09-22 2009-12-01 유앤아이 주식회사 생체분해성 금속을 포함하는 임플란트 및 이의 제조방법
KR101289122B1 (ko) * 2008-03-18 2013-07-23 한국보건산업진흥원 생체분해성 마그네슘계 합금으로 다공성 구조체의 기공이충진된 복합재 임플란트 및 이의 제조방법
JP5467294B2 (ja) 2008-06-05 2014-04-09 独立行政法人産業技術総合研究所 易成形性マグネシウム合金板材及びその作製方法
JP2011524465A (ja) * 2008-06-06 2011-09-01 ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング 吸収性マグネシウム合金
CN101629260A (zh) 2008-07-18 2010-01-20 中国科学院金属研究所 医用可吸收Mg-Zn-Mn-Ca镁合金
EP2422821B2 (en) 2009-04-22 2022-10-19 U & I Corporation Biodegradable implant and method for manufacturing same
JP5593812B2 (ja) * 2009-04-30 2014-09-24 Jfeスチール株式会社 Zn−Mg系めっき鋼板およびその製造方法
CN101658691B (zh) 2009-07-31 2013-03-13 哈尔滨工业大学 高纯度镁合金可吸收血管支架塑性加工制造方法
AU2010328809B2 (en) 2009-12-07 2014-09-11 U&I Corporation Magnesium alloy
CN102639158A (zh) 2009-12-07 2012-08-15 友和安股份公司 植入物
AT510087B1 (de) 2010-07-06 2012-05-15 Ait Austrian Institute Of Technology Gmbh Magnesiumlegierung
CN101899600B (zh) 2010-08-13 2012-04-25 上海交通大学 骨科用镁合金内植入材料及其制备方法
JP5720926B2 (ja) 2010-10-12 2015-05-20 住友電気工業株式会社 マグネシウム合金の線状体及びボルト、ナット並びにワッシャー
EP2629810A1 (en) * 2010-10-18 2013-08-28 Boston Scientific Scimed, Inc. Medical implant including a magnesium-based tie layer
SG10201504257TA (en) 2012-01-19 2015-07-30 Eth Zuerich Process and apparatus for vacuum distillation of high-purity magnesium
CN109022980A (zh) 2012-06-26 2018-12-18 百多力股份公司 镁合金、其生产方法及其用途
AU2013283537A1 (en) 2012-06-26 2014-11-06 Biotronik Ag Magnesium-zinc-calcium alloy, method for production thereof, and use thereof
US9469889B2 (en) 2012-08-31 2016-10-18 DePuy Synthes Products, Inc. Ultrapure magnesium alloy with adjustable degradation rate
WO2014159328A1 (en) 2013-03-14 2014-10-02 DePuy Synthes Products, LLC Magnesium alloy with adjustable degradation rate
US9593397B2 (en) 2013-03-14 2017-03-14 DePuy Synthes Products, Inc. Magnesium alloy with adjustable degradation rate

Also Published As

Publication number Publication date
JP2015532685A (ja) 2015-11-12
CN104755644A (zh) 2015-07-01
CN111304504A (zh) 2020-06-19
US9469889B2 (en) 2016-10-18
IN2015DN01751A (https=) 2015-05-29
US20140065009A1 (en) 2014-03-06
JP6752575B2 (ja) 2020-09-09
CA2883268C (en) 2021-01-05
TWI640638B (zh) 2018-11-11
CA2883268A1 (en) 2014-03-06
JP2019049056A (ja) 2019-03-28
EP2890824A1 (en) 2015-07-08
EP2890824B1 (en) 2019-04-17
KR20150050586A (ko) 2015-05-08
BR112015004503A2 (pt) 2017-07-04
KR102275471B1 (ko) 2021-07-13
US10213522B2 (en) 2019-02-26
TW201422822A (zh) 2014-06-16
US20170000925A1 (en) 2017-01-05
WO2014036262A1 (en) 2014-03-06

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